Zobrazeno 1 - 10
of 177
pro vyhledávání: '"Anna, Bigas"'
Autor:
Roshana Thambyrajah, Maria Maqueda, Muhammad Zaki Fadlullah, Martin Proffitt, Wen Hao Neo, Yolanda Guillén, Marta Casado-Pelaez, Patricia Herrero-Molinero, Carla Brujas, Noemi Castelluccio, Jessica González, Arnau Iglesias, Laura Marruecos, Cristina Ruiz-Herguido, Manel Esteller, Elisabetta Mereu, Georges Lacaud, Lluis Espinosa, Anna Bigas
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Recent findings suggest that Hematopoietic Stem Cells (HSC) and progenitors arise simultaneously and independently of each other already in the embryonic aorta-gonad mesonephros region, but it is still unknown how their different features ar
Externí odkaz:
https://doaj.org/article/e2c4801c11ca4edbbdc98a6129f4d110
Autor:
Roshana Thambyrajah, Maria Maqueda, Wen Hao Neo, Kathleen Imbach, Yolanda Guillén, Daniela Grases, Zaki Fadlullah, Stefano Gambera, Francesca Matteini, Xiaonan Wang, Fernando J. Calero-Nieto, Manel Esteller, Maria Carolina Florian, Eduard Porta, Rui Benedito, Berthold Göttgens, Georges Lacaud, Lluis Espinosa, Anna Bigas
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Hematopoietic stem cells (HSCs) develop from the hemogenic endothelium (HE) in the aorta- gonads-and mesonephros (AGM) region and reside within Intra-aortic hematopoietic clusters (IAHC) along with hematopoietic progenitors (HPC). The signal
Externí odkaz:
https://doaj.org/article/89ff244b2ed24e0cb8b752459be716ea
Autor:
Lili Kotmayer, Emilia Kozyra, Maximilian Kaiser, Michael Dworzak, Barbara De Moerloose, Jan Starý, Henrik Hasle, Kirsi Jahnukainen, Sophia Polychronopoulou, Krisztián Kállay, Owen Smith, Shlomit Barzilai, Riccardo Masetti, Jochen Buechner, Marek Ussowicz, Paula Kjollerstrom, Ivana Boďová, Marko Kavcic, Albert Catala, Dominik Turkiewicz, Markus Schmugge, Valérie De Haas, Rebecca Voss, Anna Bigas, Damia Romero, Csaba Bödör, Miriam Erlacher, Alessandra Giorgetti, Charlotte Niemeyer, Marcin Wlodarski
Publikováno v:
EJC Paediatric Oncology, Vol 2, Iss , Pp 100051- (2023)
Externí odkaz:
https://doaj.org/article/c011b85abdfb4cc3bb60ff8c8419145c
Autor:
Violeta García‐Hernández, David Arambilet, Yolanda Guillén, Teresa Lobo‐Jarne, María Maqueda, Christos Gekas, Jessica González, Arnau Iglesias, Nerea Vega‐García, Inés Sentís, Juan L Trincado, Ian Márquez‐López, Holger Heyn, Mireia Camós, Lluis Espinosa, Anna Bigas
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 2, Pp 1-17 (2023)
Abstract Understanding the molecular mechanisms that contribute to the appearance of chemotherapy resistant cell populations is necessary to improve cancer treatment. We have now investigated the role of β‐catenin/CTNNB1 in the evolution of T‐ce
Externí odkaz:
https://doaj.org/article/6d549c35fe4041b3aab8286bb2e7461c
Autor:
Javier Robles‐Valero, Lucía Fernández‐Nevado, Myriam Cuadrado, Luis Francisco Lorenzo‐Martín, Isabel Fernández‐Pisonero, Antonio Abad, Esther Redín, Luis Montuenga, Dionisio Martín‐Zanca, Anna Bigas, Moisés Mallo, Mercedes Dosil, Xosé R. Bustelo
Publikováno v:
Molecular Oncology, Vol 16, Iss 19, Pp 3533-3553 (2022)
Mutations in the VAV1 guanine nucleotide exchange factor 1 have been recently found in peripheral T cell lymphoma and nonsmall‐cell lung cancer (NSCLC). To understand their pathogenic potential, we generated a gene‐edited mouse model that express
Externí odkaz:
https://doaj.org/article/72b8a9a8be78472ba69e39341cfb3818
Autor:
Oskar Marin-Bejar, Damia Romero-Moya, Javier Rodriguez-Ubreva, Maximiliano Distefano, Francesca Lessi, Paolo Aretini, Alessandro Liquori, Julio Castaño, Emilia Kozyra, Lili Kotmayer, Clara Bueno, José Cervera, José Carlos Rodriguez-Gallego, Josep F Nomdedeu, Laura Murillo-Sanjuán, Cristina Díaz de Heredia, Antonio Pérez-Martinez, Félix López-Cardenas, Carolina Martínez-Laperche, Nieves Dorado-Herrero, Francisco M Marco, Felipe Prósper, Pablo Menendez, David Valcárcel, Esteban Ballestar, Csaba Bödör, Anna Bigas, Albert Catalá, Marcin W Wlodarski, Alessandra Giorgetti
Publikováno v:
HemaSphere, Vol 7, p e891194b (2023)
Externí odkaz:
https://doaj.org/article/73cdfb6289c94ebfa4e147d1498cc8f1
Autor:
Damia Romero-Moya, Oskar Marin-Bejar, Maximiliano Distefano, Joan Pera, Julio Castaño, Jessica Gonzalez, Lili Kotmayer, Csaba Bödör, Albert Català, Marcin W Wlodarski, Anna Bigas, Alessandra Giorgetti
Publikováno v:
HemaSphere, Vol 7, p e83481ae (2023)
Externí odkaz:
https://doaj.org/article/97f62a70f6314b658d5e88da7fef8376
Autor:
Laura Solé, Teresa Lobo-Jarne, Daniel Álvarez-Villanueva, Josune Alonso-Marañón, Yolanda Guillén, Marta Guix, Irene Sangrador, Catalina Rozalén, Anna Vert, Antonio Barbachano, Joan Lop, Marta Salido, Beatriz Bellosillo, Raquel García-Romero, Marta Garrido, Jessica González, María Martínez-Iniesta, Erika López-Arribillaga, Ramón Salazar, Clara Montagut, Ferrán Torres, Mar Iglesias, Toni Celià-Terrassa, Alberto Muñoz, Alberto Villanueva, Anna Bigas, Lluís Espinosa
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The failure of chemotherapy in colorectal cancer is currently unclear. Here, the authors show that upon sub-lethal dose of chemotherapy wild-type p53 colorectal cancers acquire a quiescence-like phenotype and a YAP-dependent fetal-like intestinal ste
Externí odkaz:
https://doaj.org/article/a95e4335e7804b569fac9baa390c372b
Autor:
Oskar Marin-Bejar, Damia Romero-Moya, Javier Rodriguez-Ubreva, Maximiliano Distefano, Francesca Lessi, Paolo Aretini, Alessandro Liquori, Julio Castaño, Emilia Kozyra, Lili Kotmayer, Clara Bueno, José Cervera, José Carlos Rodriguez-Gallego, Josep F Nomdedeu, Laura Murillo-Sanjuán, Cristina Díaz de Heredia, Antonio Pérez-Martinez, Félix López-Cadenas, Carolina Martínez-Laperche, Nieves Dorado-Herrero, Francisco M Marco, Felipe Prósper, Pablo Menendez, David Valcárcel, Esteban Ballestar, Csaba Bödör, Anna Bigas, Albert Catalá, Marcin W Wlodarski, Alessandra Giorgetti
Publikováno v:
Haematologica, Vol 108, Iss 9 (2023)
Externí odkaz:
https://doaj.org/article/64a9f674d5c1431a8af78aa2de7d0937
Autor:
Celia González-Gil, Mireia Morgades, Thaysa Lopes, Francisco Fuster-Tormo, Jesús García-Chica, Ran Zhao, Pau Montesinos, Anna Torrent, Marina Diaz-Beya, Rosa Coll, Lourdes Hermosín, Santiago Mercadal, José González-Campos, Lurdes Zamora, Teresa Artola, Ferran Vall-Llovera, Mar Tormo, Cristina Gil-Cortés, Pere Barba, Andrés Novo, Jordi Ribera, Teresa Bernal, Paula López de Ugarriza, María-Paz Queipo, Pilar Martínez-Sánchez, Alicia Giménez, Teresa González-Martínez, Antonia Cladera, José Cervera, Rosa Fernández-Martín, María Ángeles Ardaiz, María Jesús Vidal, Ángela Baena, Nuria López-Bigas, Anna Bigas, Jaroslaw Maciejewski, Alberto Orfao, Josep Maria Ribera, Eulalia Genescà
Publikováno v:
Haematologica, Vol 108, Iss 4 (2022)
Genetic information has been crucial to understand the pathogenesis of T-cell acute lymphoblastic leukemia (T-ALL) at diagnosis and at relapse, but still nowadays has a limited value in a clinical context. Few genetic markers are associated with the
Externí odkaz:
https://doaj.org/article/f665c159564e43d48e5cdc5fc6bc2db5