Zobrazeno 1 - 10
of 54
pro vyhledávání: '"AnnMarie C. O'Donoghue"'
Autor:
Victoria L. Linthwaite, Joanna M. Janus, Adrian P. Brown, David Wong-Pascua, AnnMarie C. O’Donoghue, Andrew Porter, Achim Treumann, David R. W. Hodgson, Martin J. Cann
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Carbon dioxide can interact with proteins to form carbamate post-translational modifications. Here, the authors developed a strategy to identify carbamate post-translational modifications by trapping carbon dioxide and subsequently identifying the ca
Externí odkaz:
https://doaj.org/article/39b39b2a296d41bd94eede4b0d506363
Publikováno v:
Catalysts, Vol 11, Iss 9, p 1055 (2021)
Organocatalysis by N-heterocyclic carbenes is normally initiated by the deprotonation of precursor azolium ions to form active nucleophilic species. Substituent effects on deprotonation have an impact on catalytic efficiency and provide insight into
Externí odkaz:
https://doaj.org/article/16f68653920e42c8982a94a13dabdcfd
Autor:
Jacob A. Grant, Zhou Lu, David E. Tucker, Bryony M. Hockin, Dmitry S. Yufit, Mark A. Fox, Ritu Kataky, Victor Chechik, AnnMarie C. O’Donoghue
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-6 (2017)
Blatter’s radicals are highly valuable stable organic free radicals, comprising a heterocyclic ring system functionalized with a heteroaryl or alkyl group at the C-3 position. Here, the authors report a synthetic strategy to obtain Blatter’s radi
Externí odkaz:
https://doaj.org/article/9fde64cbd7a442cfb61319e4c9fe420e
Autor:
Victoria L. Linthwaite, Joanna M. Janus, Adrian P. Brown, David Wong-Pascua, AnnMarie C. O’Donoghue, Andrew Porter, Achim Treumann, David R. W. Hodgson, Martin J. Cann
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The original version of this Article omitted the following from the Acknowledgements: ‘This work was support by EPSRC grant EP/K504336/1 and Leverhulme Trust grant RPG-2016-017.’ This has been corrected in both the PDF and HTML versions of the Ar
Externí odkaz:
https://doaj.org/article/e9fea854a5b0483ba7fe32f22501ce5b
Publikováno v:
The Journal of Organic Chemistry, 2023 [Peer Reviewed Journal]
Many enzymes work in tandem with small molecule cofactors, which have inspired organocatalyst designs. Chemical modification of cofactor scaffolds has increased organocatalytic reactivity and reaction scope. This synopsis presents a selection of rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226cdc2b09e358e464892d8532f85603
http://dro.dur.ac.uk/38535/1/38535.pdf
http://dro.dur.ac.uk/38535/1/38535.pdf
Autor:
Zhuan Duan, Claire M. Young, Jiayun Zhu, Alexandra M. Z. Slawin, AnnMarie C. O'Donoghue, Andrew D. Smith
Publikováno v:
Chemical Science, 2023, Vol.14(1), pp.162-170 [Peer Reviewed Journal]
Authors thank the EPSRC (JZ and CMY, EP/S020713/1 and EP/S019359/1) and ZD (CSC St Andrews PhD studentship) for funding. Heteroaromatic aldehydes are often used preferentially or exclusively in a range of NHC-catalysed processes that proceed through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38696648f68f21d77ccd2eb594f79759
https://hdl.handle.net/10023/26534
https://hdl.handle.net/10023/26534
Autor:
Claire M. Young, Christopher J. Collett, Andrew D. Smith, AnnMarie C. O'Donoghue, Richard S. Massey
Publikováno v:
European Journal of Organic Chemistry, 2021, Vol.2021(26), pp.3670-3675 [Peer Reviewed Journal]
Funding: Engineering and Physical Sciences Research Council (Grant Number(s): EP/E03795X/1, EP/S019359/1). Mechanistic studies of the triazolium ion‐catalyzed intramolecular Stetter reaction using initial rates analysis in NEt3/NEt3. HCl buffered m
Autor:
Jiayun Zhu, Inmaculada Moreno, Peter Quinn, Dmitry S. Yufit, Lijuan Song, Claire M. Young, Zhuan Duan, Andrew R. Tyler, Paul G. Waddell, Michael J. Hall, Michael R. Probert, Andrew D. Smith, AnnMarie C. O’Donoghue
Publikováno v:
Journal of organic chemistry, 2022, Vol.87(6), pp.4241-4253 [Peer Reviewed Journal]
Authors thank the EPSRC (JZ and CMY, EP/S020713/1; PQ, EP/M506321/1), ZD (CSC St Andrews PhD studentship), Universidad de Castilla-La Mancha and the European Regional Development Fund (IM) and the BBSRC (MJH, MRP and ART, BB/L013754/1) for funding. B
Autor:
Oliver R. Maguire, AnnMarie C. O'Donoghue, Matthew Rees, Steven L. Cobb, Bethany Taylor, Christopher J. Hayes, Eleanor M. Higgins, Nigel S. Simpkins
Publikováno v:
Chemical Science
The acidity of the α-proton in peptides has an essential role in numerous biochemical reactions and underpins their stereochemical integrity, which is critical to their biological function. We report a detailed kinetic and computational study of the
Autor:
Jacob Murray, Richard S. Massey, Jiayun Zhu, Andrew D. Smith, Christopher J. Collett, AnnMarie C. O'Donoghue
Publikováno v:
Organic & biomolecular chemistry, 2021, Vol.19(2), pp.387-393 [Peer Reviewed Journal]
Steady-state kinetic and structure–activity studies of a series of six triazolium-ion pre-catalysts 2a–2f were investigated for the benzoin condensation. These data provide quantitative insight into the role of triazolium N-aryl substitution unde