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pro vyhledávání: '"Ann-Marie Waltos"'
Autor:
Carlos Gonzalez, Stephen F. Carr, Elsie M. Eugui, Rebecca A. Stephenson, Fidencio Franco, Peter H. Nelson, Ann-Marie Waltos, Eric Brian Sjogren, Sussan Rouhafza, Francisco Xavier Talamas, Ronald Charles Hawley, Devens Bruce H, David G. Loughhead, Robert James Weikert, Patterson John W, Eva Papp, David J. Milan, John C. Wu, David Bernard Smith
Publikováno v:
Journal of Medicinal Chemistry. 39:4181-4196
Structure-activity relationships in the region of the phthalide ring of the inosine monophosphate dehydrogenase inhibitor mycophenolic acid have been explored. Replacement of the lactone ring with other cyclic moieties resulted in loss of potency, es