Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ann-Christin Nyström"'
Autor:
Duong T. Nguyen, Matthew O’Hara, Cecilia Graneli, Ryan Hicks, Tasso Miliotis, Ann-Christin Nyström, Sara Hansson, Pia Davidsson, Li-Ming Gan, Maria Chiara Magnone, Magnus Althage, Sepideh Heydarkhan-Hagvall
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Despite improvements in pre-clinical drug testing models, predictability of clinical outcomes continues to be inadequate and costly due to poor evidence of drug metabolism. Humanized miniature organs integrating decellularized rodent organs
Externí odkaz:
https://doaj.org/article/4df7ae2b4a4f4e15a84d4f112a0c0c0b
Autor:
Linda Sundström, Susanna Myhre, Monika Sundqvist, Andrea Ahnmark, William McCoull, Piotr Raubo, Sam D Groombridge, Magnus Polla, Ann-Christin Nyström, Lisbeth Kristensson, Mats Någård, Maria Sörhede Winzell
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189060 (2017)
The mechanism behind the glucose lowering effect occurring after specific activation of GPR120 is not completely understood. In this study, a potent and selective GPR120 agonist was developed and its pharmacological properties were compared with the
Externí odkaz:
https://doaj.org/article/0ae7af91f78b4d848a82f18a857194db
Autor:
Kevin Randall, Neil Henderson, Jaimini Reens, Sonia Eckersley, Ann-Christin Nyström, Marie C South, Clare A Balendran, Gerhard Böttcher, Glen Hughes, Sally A Price
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162076 (2016)
Ulcerative colitis is a chronic inflammatory disease affecting the colon and is characterized by epithelial damage and barrier dysfunction. Upregulation of the tight junction protein claudin-2 by cytokines is hypothesized to contribute to the dysregu
Externí odkaz:
https://doaj.org/article/80c17657d66a47ec82ee182e61c58415
Autor:
Magnus Althage, Ryan Hicks, Cecilia Graneli, Pia Davidsson, Li-Ming Gan, Ann-Christin Nyström, Maria Chiara Magnone, Matthew O’Hara, Sepideh Heydarkhan-Hagvall, Sara F. Hansson, Tasso Miliotis, Duong T. Nguyen
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
Scientific Reports
Despite improvements in pre-clinical drug testing models, predictability of clinical outcomes continues to be inadequate and costly due to poor evidence of drug metabolism. Humanized miniature organs integrating decellularized rodent organs with tiss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d30c346a395fab5f23c2da1f402de5f
https://doaj.org/article/4df7ae2b4a4f4e15a84d4f112a0c0c0b
https://doaj.org/article/4df7ae2b4a4f4e15a84d4f112a0c0c0b
Autor:
Patrik Johansson, Elisabeth Ax, Ann-Christin Nyström, Joachim Maier, Lovisa Holmberg Schiavone, Anna Jansson, Agnes Csiszar
Publikováno v:
The Journal of biological chemistry. 292(37)
Production and secretion of pro-metastatic proteins is a feature of many tumor cells. The FAM3C interleukin-like epithelial-to-mesenchymal-transition (EMT) inducer (ILEI) has been shown to be strongly up-regulated in several cancers and to be essenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4c02e1da8dcc2ee2691353aa198622a
https://pubmed.ncbi.nlm.nih.gov/28751379
https://pubmed.ncbi.nlm.nih.gov/28751379
Autor:
Lisbeth Kristensson, Maria Sörhede Winzell, Sam D. Groombridge, Piotr Raubo, Andrea Ahnmark, William McCoull, Monika Sundqvist, Susanna Myhre, Polla Magnus, Ann-Christin Nyström, Linda Sundström, Mats Någård
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189060 (2017)
PLoS ONE
PLoS ONE
The mechanism behind the glucose lowering effect occurring after specific activation of GPR120 is not completely understood. In this study, a potent and selective GPR120 agonist was developed and its pharmacological properties were compared with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d403700840ffcd7ea5ecb0444d62da4b
http://europepmc.org/articles/PMC5716539?pdf=render
http://europepmc.org/articles/PMC5716539?pdf=render
Autor:
Jörgen Östling, Pablo Garrido Cuesta, Mutsumi Katayama, Thais de Castro Barbosa, Ann-Christin Nyström, Lubna Al-Khalili, Julie Massart, Megan E. Osler, Juleen R. Zierath, Jan Oscarsson
Publikováno v:
American Journal of Physiology-Cell Physiology. 307:C774-C787
Two-dimensional difference gel electrophoresis (2-D DIGE)-based proteome analysis has revealed intrinsic insulin resistance in myotubes derived from type 2 diabetic patients. Using 2-D DIGE-based proteome analysis, we identified a subset of insulin-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::080b96b87b66d2df6c3878cab45c9ce8
https://doi.org/10.1152/ajpcell.00110.2014
https://doi.org/10.1152/ajpcell.00110.2014
Publikováno v:
The Protein Journal
Recombinant human FIX concentrates (rhFIX) are essential in the treatment and prevention of bleeding in the bleeding disorder haemophilia B. However, due to the complex nature of FIX production yields are low which leads to high treatment costs. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9127ac5256581638fa0e9cdbbbdc0754
http://europepmc.org/articles/PMC3947961
http://europepmc.org/articles/PMC3947961
Publikováno v:
Protein Expression and Purification. 89:189-195
Effective anti-diabetic drugs known as thiazolidinediones (e.g. rosiglitazone, pioglitazone) exert their therapeutic effects through their agonistic activity at the peroxisome proliferator-activated receptor gamma (PPARγ). As a multidomain transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::467b9174fc0c4ac23f70e9af1b01f4d4
https://doi.org/10.1016/j.pep.2013.03.012
https://doi.org/10.1016/j.pep.2013.03.012
Autor:
Sally A. Price, Glen Hughes, Kevin J. Randall, Clare A. Balendran, Gerhard Böttcher, Sonia Eckersley, Neil Henderson, Ann-Christin Nyström, Marie C. South, Jaimini Reens
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 9, p e0162076 (2016)
PLoS ONE, Vol 11, Iss 9, p e0162076 (2016)
Ulcerative colitis is a chronic inflammatory disease affecting the colon and is characterized by epithelial damage and barrier dysfunction. Upregulation of the tight junction protein claudin-2 by cytokines is hypothesized to contribute to the dysregu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03547f0caea064bb522d3dbe3fe7ff74
https://pubmed.ncbi.nlm.nih.gov/27598247
https://pubmed.ncbi.nlm.nih.gov/27598247