Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ann-Christin Gaupel"'
Autor:
Yonghe Wu, Michael Fletcher, Zuguang Gu, Qi Wang, Barbara Costa, Anna Bertoni, Ka-Hou Man, Magdalena Schlotter, Jörg Felsberg, Jasmin Mangei, Martje Barbus, Ann-Christin Gaupel, Wei Wang, Tobias Weiss, Roland Eils, Michael Weller, Haikun Liu, Guido Reifenberger, Andrey Korshunov, Peter Angel, Peter Lichter, Carl Herrmann, Bernhard Radlwimmer
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Glioblastoma is divided into four subtypes based on molecular profiling at the methylome and transcriptome level. Here the authors perform an integrative analysis of these subtypes resulting in the identification of SOX10 whose loss induces a mesench
Externí odkaz:
https://doaj.org/article/50c3ca33473a428aa36c9a52cf6638ef
Autor:
Christoph Schifflers, Philipp M. Roessner, Marit Krötschel, Fabian Kilpert, Stephan Stilgenbauer, Leopold Sellner, Ekaterina Lupar, Ana Izcue, Sascha Dietrich, Marie Bordas, Ann-Christin Gaupel, Lavinia Arseni, Sebastian J. Arnold, Tobias Roider, Martina Seiffert, Laura Llaó Cid, Dolors Colomer, Peter Lichter
Publikováno v:
Leukemia
Roessner, P M, Llaó Cid, L, Lupar, E, Roider, T, Bordas, M, SCHIFFLERS, C, Arseni, L, Gaupel, A-C, Kilpert, F, Krötschel, M, Arnold, S J, Sellner, L, Colomer, D, Stilgenbauer, S, Dietrich, S, Lichter, P, Izcue, A & Seiffert, M 2021, ' EOMES and IL-10 regulate antitumor activity of T regulatory type 1 CD4 + T cells in chronic lymphocytic leukemia ', Leukemia, vol. 35, no. 8, pp. 2311-2324 . https://doi.org/10.1038/s41375-021-01136-1
Leukemia : normal and malignant hemopoiesis 35(8), 2311-2324 (2021). doi:10.1038/s41375-021-01136-1
Leukemia : the Journal of Normal and Malignant Hemopoiese ; Official Journal of the Leukemia Research Fund U.K.
Roessner, P M, Llaó Cid, L, Lupar, E, Roider, T, Bordas, M, SCHIFFLERS, C, Arseni, L, Gaupel, A-C, Kilpert, F, Krötschel, M, Arnold, S J, Sellner, L, Colomer, D, Stilgenbauer, S, Dietrich, S, Lichter, P, Izcue, A & Seiffert, M 2021, ' EOMES and IL-10 regulate antitumor activity of T regulatory type 1 CD4 + T cells in chronic lymphocytic leukemia ', Leukemia, vol. 35, no. 8, pp. 2311-2324 . https://doi.org/10.1038/s41375-021-01136-1
Leukemia : normal and malignant hemopoiesis 35(8), 2311-2324 (2021). doi:10.1038/s41375-021-01136-1
Leukemia : the Journal of Normal and Malignant Hemopoiese ; Official Journal of the Leukemia Research Fund U.K.
Leukemia : normal and malignant hemopoiesis 35(8), 2311-2324 (2021). doi:10.1038/s41375-021-01136-1
Published by Springer Nature, London
Published by Springer Nature, London
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad29609cd7bbac02e747ba09a8e7c32
https://doi.org/10.1038/s41375-021-01136-1
https://doi.org/10.1038/s41375-021-01136-1
Autor:
Bernhard Radlwimmer, Ann Christin Gaupel, Yonghe Wu, Magdalena Schlotter, Wei Wang, Hai-Kun Liu, Qi Wang, Ka Hou Man, Michael N. C. Fletcher, Andrey Korshunov, Peter Angel, Zuguang Gu, Michael Weller, Martje Barbus, Jörg Felsberg, Barbara Costa, Anna Marta Maria Bertoni, Carl Herrmann, Peter Lichter, Tobias Weiss, Roland Eils, Guido Reifenberger, Jasmin Mangei
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Nature Communications
Nature Communications
Glioblastoma frequently exhibits therapy-associated subtype transitions to mesenchymal phenotypes with adverse prognosis. Here, we perform multi-omic profiling of 60 glioblastoma primary tumours and use orthogonal analysis of chromatin and RNA-derive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1fc95721f03416553e86b58fdc63415
https://doaj.org/article/50c3ca33473a428aa36c9a52cf6638ef
https://doaj.org/article/50c3ca33473a428aa36c9a52cf6638ef
Autor:
Sascha Dietrich, Philipp M. Roessner, Marit Krötschel, Ekaterina Lupar, Peter Lichter, Ana Izcue, S. Stilgenbauer, Christoph Schifflers, Marie Bordas, Tobias Roider, Martina Seiffert, Laura Llaó Cid, Ann Christin Gaupel, Leopold Sellner, Fabian Kilpert, Sebastian J. Arnold
The transcription factor Eomesodermin (EOMES) promotes IL-10 production of CD4+T-cells, which has been linked to immunosuppressive and cytotoxic activities. We detected EOMES-expressing CD4+T-cells in lymph node samples of patients with chronic lymph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85a787e7911fdea0543b4321f6737917
https://doi.org/10.1101/2020.03.09.983098
https://doi.org/10.1101/2020.03.09.983098
Autor:
Bernhard Radlwimmer, Gernot Poschet, Yonghe Wu, Karsten Hiller, Lidia Santos Silva, Peter Lichter, Yannic Nonnenmacher, Holger M. Becker, Magdalena Schlotter, Sean C. Sapcariu, Ann Christin Gaupel, Niclas Kneisel, Rüdiger Hell, Martina Seiffert
Publikováno v:
EMBO reports. 18:2172-2185
Elevated amino acid catabolism is common to many cancers. Here, we show that glioblastoma are excreting large amounts of branched‐chain ketoacids (BCKAs), metabolites of branched‐chain amino acid (BCAA) catabolism. We show that efflux of BCKAs, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e06ac8bc0b6eecda04079705afcd0bf
https://doi.org/10.15252/embr.201744154
https://doi.org/10.15252/embr.201744154
Publikováno v:
Journal of Cellular Biochemistry. 116:1982-1992
To identify chemical genetic interactions underlying the mechanism of action of histone deacetylase inhibitors (HDACi) a yeast deletion library was screened for hypersensitive deletion mutants that confer increased sensitivity to the HDACi, CG-1521.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::099edbb6f44047b7c81d01c5aac40677
https://doi.org/10.1002/jcb.25153
https://doi.org/10.1002/jcb.25153
Publikováno v:
Journal of cellular biochemistry. 116(9)
To identify chemical genetic interactions underlying the mechanism of action of histone deacetylase inhibitors (HDACi) a yeast deletion library was screened for hypersensitive deletion mutants that confer increased sensitivity to the HDACi, CG-1521.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c1a6269aa87f2ac3bda4245c208c17ba
https://pubmed.ncbi.nlm.nih.gov/25755069
https://pubmed.ncbi.nlm.nih.gov/25755069
Publikováno v:
BMC Genomics
Background Previous studies from our laboratory and others have demonstrated that in addition to altering chromatin acetylation and conformation, histone deacetylase inhibitors (HDACi) disrupt the acetylation status of numerous transcription factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2772c8dbcf23fdf7ad1cd958c6d7ffa8
https://pubmed.ncbi.nlm.nih.gov/24968945
https://pubmed.ncbi.nlm.nih.gov/24968945
Autor:
Bernhard Aigner, Akira Andoh, Lina Badimon, Alexandre Benani, Ross A. Breckenridge, Daniel Butzke, Andrew V. Caprariello, Laura Casani, Lucas M. Chaible, Li Chen, Mengqi Chen, K. Yeon Choi, Mohammed Emamussalehin Choudhury, Iain J. Clarke, Kristine Coleman, John L. Daiss, Frédérique Datiche, Catherine M. Davis, Geoffrey A. Donnan, David Feifel, Peter Fickert, Marcus A. Finzi Corat, Xavier Fioramonti, Christopher H. Fry, Sharyl Fyffe-Maricich, Ann-Christin Gaupel, Steven R. Goldberg, Yoichi Gondo, Barbara Grune, Belinda A. Henry, David W. Howells, Joshua G. Hunter, Soudabeh Imanikia, Rita I. Jabr, Naoto Kadoguchi, Lixin Kan, Jiro Kasahara, Stephen L. Kates, Matthew W. Kemp, Barbara Kessler, Saeed R. Khan, Denise Kinoshita, Nikolai Klymiuk, Ryuta Koyama, Doris Kretzschmar, Josephine Kugler, Jitka Kuncova, Maki Kuro, Mayuko Kurome, Michael Lardelli, Heather A. Lawson, Edmund Chun Yu Lee, Corinne Leloup, Lars Lewejohann, Manfred Liebsch, Fabienne Lienard, James Lokensgard, Andreas Luch, Malcolm R. Macleod, Meghan E. McGee-Lawrence, Alistair McGregor, Robert H. Miller, Atsushi Mizoguchi, Sarah Mordan-McCombs, Gabrielle C. Musk, Aysegul Nalca, Masahiro Nomoto, Victoria E. O’Collins, Michael Oelgeschläger, Christoph H. Österreicher, Luc Penicaud, Marion J. Pollheimer, Simone Renner, Sara I. Ruiz, Masatoshi Saito, Scott Schachtele, Steven J. Schapiro, Charles W. Schindler, Edward M. Schwarz, Frank J. Secreto, Andrea Seiler, Angela L. Shamchuk, Richard P. Shannon, You-Tang Shen, Paul D. Shilling, Dana Sittner, Gideon P. Smith, Milan Stengl, Stephen R. Stürzenbaum, Jitka Sviglerova, Farhan A. Syed, Jerrold Tannenbaum, Martin Tenniswood, Louise Thibault, Keith B. Tierney, Michael Trauner, Airo Tsubura, Judith Axler Turner, Giuseppe Verdile, Gemma Vilahur, Wei-Lin Winnie Wang, James L. Weed, JoEllen Welsh, Steffi Werler, Joachim Wistuba, Eckhard Wolf, Annegret Wünsch, Toshiyuki Yamamoto, Hironori Yokoyama, Katsuhiko Yoshizawa, Maria L. Zaidan Dagli, Caroline J. Zeiss, Elizabeth E. Zumbrun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16f8e600be6cf2585fa623d35f190cc0
https://doi.org/10.1016/b978-0-12-415894-8.01002-2
https://doi.org/10.1016/b978-0-12-415894-8.01002-2
Autor:
JoEllen Welsh, Sarah Mordan-McCombs, Martin Tenniswood, Wei-Lin Winnie Wang, Theodore Brown, Ann-Christin Gaupel
Previous studies have suggested that 1,25 dihydroxyvitamin D(3) (1,25(OH)2D3) induces cell cycle arrest and/or apoptosis in prostate cancer cells in vitro, suggesting that vitamin D may be a useful adjuvant therapy for prostate cancer and a chemoprev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59983af4cac244b6ca63e56ce9ee7b5a
https://europepmc.org/articles/PMC4211603/
https://europepmc.org/articles/PMC4211603/