Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ann-Charlotte Leandersson"'
Autor:
B. Hejdeman, Eric Sandström, Eva-Lena Fredriksson, Ann-Charlotte Leandersson, G. Bratt, Britta Wahren
Publikováno v:
HIV Medicine. 4:101-110
Objective To study the impact of effective highly active antiretroviral therapy (HAART) on the preservation of long-term CD4 memory cells induced by vaccines in HIV-1-infected patients. Methods Thirty HIV-1-positive patients on HAART with undetectabl
Autor:
Thomas Leitner, Lars E. Eriksson, Kerstin I. Falk, Göran Bratt, Ann-Charlotte Leandersson, Britta Wahren
Publikováno v:
AIDS Research and Human Retroviruses. 19:259-265
We studied the pattern of HIV-1 DNA development and the association to other HIV-related factors during long-term supervised therapy interruption (LT-STI). Fifteen patients were treated with long-time protease inhibitor-based antiretroviral therapy (
Autor:
Ewa Björling, Åsa Björndal, Ann-Charlotte Leandersson, Jan Albert, Andreas Mörner, Marianne Jansson
Publikováno v:
AIDS Research and Human Retroviruses. 18:193-200
Primary human immunodeficiency virus type 2 (HIV-2) isolates are characterized by their ability to use a broad range of coreceptors, including CCR5, CXCR4, and several alternative coreceptors. However, the in vivo relevance of this in vitro promiscui
Autor:
Michael Levi, Eric Sandström, Göran Bratt, Karl Ljungberg, Sandra A. Calarota, A. Kjerrström Zuber, Ann-Charlotte Leandersson, B. Hejdeman, Jorma Hinkula, Erik Rollman, Britta Wahren, Bartek Zuber
Publikováno v:
Vaccine, 20(15), 1988-1993. Elsevier BV
Clinical and experimental studies of HIV-1 subcomponents were made in order to increase their immunogenicity. HIV subtype envelopes A, B and C have been compared and a detailed analysis made by peptides of the coreceptor–ligand interactions. We ide
Autor:
Peter Lundholm, Ann-Charlotte Leandersson, G. Bratt, Britta Wahren, Birger Christensson, Eric Sandström
Publikováno v:
Virus Research. 82:141-145
This is a demonstration of immune activation by delivery of genetic vaccines in human mucosa. We analyzed the local and systemic responses in HIV-1 infected individuals following intraoral jet-injections of HIV-1 DNA constructs encoding the nef, rev,
Autor:
R. Lenkei, Eric Sandström, Britta Wahren, Ann-Charlotte Leandersson, G. Bratt, A.L. Hultström, B. Hejdeman
Publikováno v:
AIDS Research and Human Retroviruses. 17:277-286
Both naive and memory T lymphocyte responses are lost during advanced HIV infection. Treatment with highly active antiretroviral therapy (HAART) is associated with an increase in T lymphocytes and a reduction in viral load. However, the viral respons
Autor:
Volker Erfle, Klas Kärre, Jorma Hinkula, Michael Levi, Adnane Achour, Britta Wahren, Johan K. Sandberg, Ann-Charlotte Leandersson, Birgit Kohleisen, Stefan Schwartz, Claudia Devito
Publikováno v:
Virology. 273:112-119
We investigated the immune response against a human immunodeficiency virus type 1 (HIV-1) nef DNA sequence administered epidermally in mice transgenic for the human major histocompatibility complex (MHC) class I molecule HLA-A201. Ten potential HLA-A
Autor:
Sandra A. Calarota, Ann-Charlotte Leandersson, Göran Bratt, Jorma Hinkula, Dennis M. Klinman, Kent J. Weinhold, Eric Sandström, Britta Wahren
Publikováno v:
The Journal of Immunology. 163:2330-2338
Intensive chemotherapy is capable of reducing the viral load in HIV-1-infected individuals while infected cells are still present. A special property of DNA immunization is to induce both new CTL and Ab responses. We evaluated the possibility of indu
Autor:
R Thorstensson, Jorma Hinkula, Britta Wahren, Per Putkonen, Ann-Charlotte Leandersson, Kenji Okuda, Stefan Schwartz, Marlene Quesada-Rolander
Publikováno v:
Virology. 250(2):293-301
The efficacy of combining immunization with human immunodeficiency vitus type 1 (HIV-1) DNA and HIV-1 recombinant proteins to obtain protection from chimeric simian/human immunodeficiency virus (SHIV) was determined. Four cynomolgus monkeys received
MT-2 tropism and CCR-5 genotype strongly influence disease progression in HIV-1-infected individuals
Publikováno v:
AIDS. 12:729-736
BACKGROUND The beta-chemokine receptor CCR-5 is the coreceptor for cellular entry by non-syncytium-inducing (NSI) HIV-1 strains that dominate early in infection. A 32 base-pair deletion (delta32) in the CCR-5 gene renders this coreceptor non-function