Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Ann-Charlotte Johansson"'
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44071 (2012)
Mortality in head and neck squamous cell carcinoma (HNSCC) is high due to emergence of therapy resistance which results in local and regional recurrences that may have their origin in resistant cancer stem cells (CSCs) or cells with an epithelial-mes
Externí odkaz:
https://doaj.org/article/05c796357f2b420b91cfbd7a5706e265
Autor:
Karin Roberg, Arne Östman, Eva Munck-Wikland, Reidar Grénman, Maja Bradic Lindh, Fredrik Jerhammar, Anna Ansell, Ann-Charlotte Johansson
A growing body of evidence suggests that components of the tumor microenvironment, including cancer-associated fibroblasts (CAF), may modulate the treatment sensitivity of tumor cells. Here, we investigated the possible influence of CAFs on the sensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aaa79859c9f4c5d9a2e5531b2b9fe70e
https://doi.org/10.1158/1541-7786.c.6541521
https://doi.org/10.1158/1541-7786.c.6541521
Autor:
Karin Roberg, Arne Östman, Eva Munck-Wikland, Reidar Grénman, Maja Bradic Lindh, Fredrik Jerhammar, Anna Ansell, Ann-Charlotte Johansson
PDF file - 91K, PCR array gene list
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e94991e1d441853d8ec2c74f64bb72b
https://doi.org/10.1158/1541-7786.22516875.v1
https://doi.org/10.1158/1541-7786.22516875.v1
Autor:
Karin Roberg, Arne Östman, Eva Munck-Wikland, Reidar Grénman, Maja Bradic Lindh, Fredrik Jerhammar, Anna Ansell, Ann-Charlotte Johansson
PDF file - 170K, Protection from cetuximab treatment is provided by cancer-associated fibroblast-derived soluble factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::941fe092660430f6e733f485a03623ce
https://doi.org/10.1158/1541-7786.22516878.v1
https://doi.org/10.1158/1541-7786.22516878.v1
Autor:
Karin Roberg, Arne Östman, Eva Munck-Wikland, Reidar Grénman, Maja Bradic Lindh, Fredrik Jerhammar, Anna Ansell, Ann-Charlotte Johansson
PDF file - 156K, Cancer-associated fibroblasts induce cetuximab resistance in head and neck squamous cell carcinoma cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bee23999cdf29ba4eb8837dd1097153
https://doi.org/10.1158/1541-7786.22516881
https://doi.org/10.1158/1541-7786.22516881
Autor:
Per-Henrik Edqvist, Karin Roberg, Ann-Charlotte Johansson, Fredrik Pontén, Stina Garvin, Adam Jedlinski
Publikováno v:
Journal of Oral Pathology & Medicine. 46:717-724
The aims of this study were to validate in vitro drug sensitivity testing of head and neck squamous cell carcinoma (HNSCC) cell lines in an in vivo xenograft model and to identify treatment-induced changes in the epidermal growth factor receptor (EGF
Publikováno v:
Journal of Oral Pathology & Medicine. 45:640-646
Background Head and neck squamous cell carcinoma (HNSCC) tumors are often therapy resistant and may originate from cancer stem cells or tumor cells with an epithelial-to-mesenchymal transition (EMT) phenotype. The aim of this study was to characteriz
Publikováno v:
Journal of Oral Pathology & Medicine. 45:9-16
Head and neck squamous cell carcinoma is frequently associated with aberrant epidermal growth factor receptor (EGFR) signaling, which contributes to tumor growth. Here, the functional importance of EGFR ligands in relation to proliferation and sensit
Autor:
Karin Roberg, Jenny Welander, Fredrik Jerhammar, Ann-Charlotte Johansson, Rebecca Ceder, Peter Söderkvist, Roland Grafström, Agneta Jansson
Publikováno v:
Oral Oncology. 50:832-839
Targeted therapy against the epidermal growth factor receptor (EGFR) only variably represents a therapeutic advance in head and neck squamous cell carcinoma (HNSCC). This study addresses the need of biomarkers of treatment response to the EGFR-target
Publikováno v:
Journal of Oral Pathology & Medicine. 42:26-36
Background: Combination treatment (chemoradiotherapy) is the standard treatment for locally advanced head and neck squamous cell carcinoma (HNSCC); however, treatment resistance and local recurrenc ...