Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ann-Charlotte Aveberger"'
Autor:
Karin Palmblad, Erik Sundberg, Huan Yang, Ann-Charlotte Aveberger, Ulf Andersson, R. Kokkola, Kevin J. Tracey, Jian Li, H. Erlandsson Harris
Publikováno v:
Arthritis & Rheumatism. 48:2052-2058
Objective Extracellular high mobility group box chromosomal protein 1 (HMGB-1) is a recently identified, endogenous, potent tumor necrosis factor– and interleukin-1 (IL-1)–inducing protein detectable in inflamed synovia in both human and experime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8edb5b306f780dc3d8c8fe12baac78eb
https://doi.org/10.1002/art.11161
https://doi.org/10.1002/art.11161
Autor:
Lena Klevenvall, Ulf Andersson, Ann Charlotte Aveberger, Hulda Sigridur Hreggvidsdottir, Helena Erlandsson Harris, Anna M. Lundberg
The nuclear protein high mobility group box protein 1 (HMGB1) promotes inflammation upon extracellular release. HMGB1 induces proinflammatory cytokine production in macrophages via Toll-like receptor (TLR)-4 signaling in a redox-dependent fashion. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0dccfeae530a71603a4e522c371fcf8
https://europepmc.org/articles/PMC3320135/
https://europepmc.org/articles/PMC3320135/
Autor:
Helena Erlandsson Harris, Hulda Sigridur Hreggvidsdottir, Ann-Charlotte Aveberger, Lars Ottosson, Lena Klevenvall, Hanna Schierbeck, Ulf Andersson, Heidi Wähämaa, Karin Palmblad, Therese Östberg
Publikováno v:
Journal of leukocyte biology. 86(3)
A prototypic mechanism for enhancement of inflammation by an endogenous molecule is described. The nuclear protein HMGB1 has previously been demonstrated to act as an alarmin and to promote inflammation upon extracellular release, yet its mode of act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d8fa45c44e2abbeec7f9ffc21896f9b
https://pubmed.ncbi.nlm.nih.gov/19564572
https://pubmed.ncbi.nlm.nih.gov/19564572
Autor:
Weiwen Jiang, Ann-Charlotte Aveberger, Cecilia K Zetterström, Hanna Schierbeck, Heidi Wähämaa, David S. Pisetsky, Helena Erlandsson Harris, Therese Östberg, Michael T. Lotze, Ulf Andersson
Publikováno v:
Journal of leukocyte biology. 83(1)
Gold compounds such as gold sodium thiomalate (GST) can reduce the symptoms of rheumatoid arthritis (RA), although their mechanism of action is not well defined. As the proinflammatory mediator high mobility group box chromosomal protein 1 (HMGB1) ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e26d7cdb9df5891cf97c9ba2d06bdbb4
https://pubmed.ncbi.nlm.nih.gov/17913975
https://pubmed.ncbi.nlm.nih.gov/17913975
Autor:
Erik Sundberg, Chris Pruunsild, Rille Pullerits, Karin Palmblad, Dirk Holzinger, Ann-Charlotte Aveberger, Helena Erlandsson Harris, Marie Fischer, Hanna Schierbeck
Publikováno v:
Annals of the Rheumatic Diseases. 71:A10.2-A11
Backgroundand objectives The endogenous danger signal High Mobility Group Box protein 1 (HMGB1) promotes inflammation. HMGB1 has been implicated as a mediator of RA while there are no reports describing its presence in JIA patient samples. HMGB1 is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c90947464de913ed650f3bee477c3bc
https://doi.org/10.1136/annrheumdis-2011-201230.23
https://doi.org/10.1136/annrheumdis-2011-201230.23
Autor:
Ann-Charlotte Aveberger, Lena Klevenvall, Ulf Andersson, Helena Erlandsson Harris, Hulda Sigridur Hreggvidsdottir, Anna M. Lundberg
Publikováno v:
Annals of the Rheumatic Diseases. 71:A80.1-A80
Background and objectives The pro-inflammatory protein HMGB1 is a pathogenic mediator in several inflammatory diseases as demonstrated by beneficial effects of HMGB1-blocking therapy in experimental models including arthritis. High levels of extracel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::464f2bdec92c5d900bf495f7adcd0c46
https://doi.org/10.1136/annrheumdis-2011-201238.19
https://doi.org/10.1136/annrheumdis-2011-201238.19
Autor:
Ulf Andersson, Therese Östberg, Lena Klevenvall, Hanna Schierbeck, Heidi Wähämaa, H Sigridur Hreggvidsdottir, Ann-Charlotte Aveberger, H. Erlandsson Harris
Publikováno v:
Annals of the Rheumatic Diseases. 69:A38-A38
The proinflammatory protein HMGB1 was recently identified as a mediator of rheumatoid arthritis (RA) and of other inflammatory diseases. This is demonstrated by extracellular HMGB1 expression both in experimental models of arthritis and in synovial b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fd0f2ad75e7bd9113e78e84988311dd
https://doi.org/10.1136/ard.2010.129627g
https://doi.org/10.1136/ard.2010.129627g
Autor:
Erik Sundberg, Karin Palmblad, Ann-Charlotte Aveberger, Helena Erlandsson Harris, Riikka Söderling, Margarita Diez, Ulf Andersson
Publikováno v:
Arthritis Research & Therapy
High-mobility group chromosomal box protein 1 (HMGB1) is a structural nuclear protein that promotes inflammation when present extracellularly. Aberrant, extracellular HMGB1 expression has been demonstrated in human and experimental synovitis. The aim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ee9486b33a58e7cb082ed2b0b7b15d
https://doi.org/10.1186/ar2155
https://doi.org/10.1186/ar2155
Autor:
Ann-Charlotte Aveberger, Helena Erlandsson-Harris, Karin Palmblad, Huan Yang, Ona Bloom, Alfred Janson, Minghuang Zhang, Ulf Andersson, Haichao Wang, R. Kokkola, Kevin J. Tracey
Publikováno v:
Karolinska Institutet
The Journal of Experimental Medicine
The Journal of Experimental Medicine
Lipopolysaccharide (LPS) is lethal to animals because it activates cytokine release, causing septic shock and tissue injury. Early proinflammatory cytokines (e.g., tumor necrosis factor [TNF] and interleukin [IL]-1) released within the first few hour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a148f2a034e1b6fbbe692d1746e16a2
http://www.ncbi.nlm.nih.gov/pubmed/10952726
http://www.ncbi.nlm.nih.gov/pubmed/10952726