Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Ann-Cathrine Radesäter"'
Autor:
Karin Kolmodin, Juliette Janson, Britt-Marie Swahn, Stefan von Berg, Tjerk Bueters, Gvido Cebers, Ann-Cathrine Radesäter, Johanna Fälting, Fredrik Jeppsson, Susanne Gustavsson, Bart Ploeger, Sofia Karlström, Susanna Eketjäll, Lise-Lotte Olsson
Publikováno v:
Journal of Biological Chemistry. 287:41245-41257
β-Site amyloid precursor protein cleaving enzyme1 (BACE1) is one of the key enzymes involved in the processing of the amyloid precursor protein (APP) and formation of amyloid β peptide (Aβ) species. Because cerebral deposition of Aβ species might
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3be78180b718cc33322fedb5df5eba93
https://doi.org/10.1074/jbc.m112.409110
https://doi.org/10.1074/jbc.m112.409110
Autor:
Fredrik Olsson, Krisztián Bogár, Per I. Arvidsson, Daniel Bergström, Paulina Appelkvist, Jonas Malmborg, Rebecka Klintenberg, Fredrik Lake, Kia Strömberg, Christian Linde, Istvan Macsari, Ellen Santangelo, Ann-Cathrine Radesäter, Kim Paulsen, Ulrika Yngve, Yevgeni Besidski, M. Sundstrom
Publikováno v:
MedChemComm. 4:422
The structure–activity relationship for a series of potent γ-secretase modulators based on the 6,7-dihydro-4H-[1,2,4]triazolo[1,5-a]pyrimidin-5-one scaffold is described. Furthermore, we report details regarding the modulator profile on Aβ proces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5803b51cc3d8de4c2971efacf9469024
https://doi.org/10.1039/c2md20312j
https://doi.org/10.1039/c2md20312j