Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ann Z Moore"'
Autor:
Roshni Roy, Pei-Lun Kuo, Julián Candia, Dimitra Sarantopoulou, Ceereena Ubaida-Mohien, Dena Hernandez, Mary Kaileh, Sampath Arepalli, Amit Singh, Arsun Bektas, Jaekwan Kim, Ann Z Moore, Toshiko Tanaka, Julia McKelvey, Linda Zukley, Cuong Nguyen, Tonya Wallace, Christopher Dunn, William Wood, Yulan Piao, Christopher Coletta, Supriyo De, Jyoti Sen, Nan-ping Weng, Ranjan Sen, Luigi Ferrucci
Publikováno v:
eLife, Vol 12 (2023)
Age-associated DNA methylation in blood cells convey information on health status. However, the mechanisms that drive these changes in circulating cells and their relationships to gene regulation are unknown. We identified age-associated DNA methylat
Externí odkaz:
https://doaj.org/article/d686b4020d774313aa1c545d7788c07b
Autor:
Toshiko Tanaka, Nathan Basisty, Giovanna Fantoni, Julián Candia, Ann Z Moore, Angelique Biancotto, Birgit Schilling, Stefania Bandinelli, Luigi Ferrucci
Publikováno v:
eLife, Vol 9 (2020)
Older age is a strong shared risk factor for many chronic diseases, and there is increasing interest in identifying aging biomarkers. Here, a proteomic analysis of 1301 plasma proteins was conducted in 997 individuals between 21 and 102 years of age.
Externí odkaz:
https://doaj.org/article/d90b5f67b19b406eb35690442335fc2e
Autor:
Ann Z Moore, Mary L Biggs, Amy Matteini, Ashley O'Connor, Sarah McGuire, Brock A Beamer, M Danielle Fallin, Linda P Fried, Jeremy Walston, Aravinda Chakravarti, Dan E Arking
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11069 (2010)
Mitochondria contribute to the dynamics of cellular metabolism, the production of reactive oxygen species, and apoptotic pathways. Consequently, mitochondrial function has been hypothesized to influence functional decline and vulnerability to disease
Externí odkaz:
https://doaj.org/article/ba82350386e04a91847b55d93c3bb6bd
Autor:
Allison B. Herman, Dimitrios Tsitsipatis, Carlos Anerillas, Krystyna Mazan-Mamczarz, Angelica E. Carr, Jordan M. Gregg, Mingyi Wang, Jing Zhang, Marc Michel, Charnae' Henry-Smith, Sophia C. Harris, Rachel Munk, Jennifer L Martindale, Yulan Piao, Jinshui Fan, Julie A. Mattison, Supriyo De, Kotb Abdelmohsen, Robert W. Maul, Toshiko Tanaka, Ann Z. Moore, Megan E. DeMouth, Simone Sidoli, Luigi Ferrucci, Yie Liu, Rafael de Cabo, Edward G. Lakatta, Myriam Gorospe
Publikováno v:
Journal of Clinical Investigation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e48b4a5815cc051611d66bc8229ef33
https://doi.org/10.1172/jci165933
https://doi.org/10.1172/jci165933
Autor:
Allison Herman, Dimitrios Tsitsipatis, Carlos Anerillas, Krystyna Mazan-Mamczarz, Angelica E. Carr, Jordan M. Gregg, Mingyi Wang, Jing Zhang, Marc Michel, Sophia C. Harris, Rachel Munk, Jennifer L. Martindale, Yulan Piao, Jinshui Fan, Julie A. Mattison, Supriyo De, Kotb Abdelmohsen, Robert W. Maul, Toshiko Tanaka, Ann Z. Moore, Megan E. DeMouth, Simone Sidoli, Luigi Ferrucci, Rafael De Cabo, Edward G. Lakatta, Myriam Gorospe
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6c9bbfb1813e255393b987894db586a
https://doi.org/10.2139/ssrn.4186256
https://doi.org/10.2139/ssrn.4186256
Autor:
Laura Beth J. McIntire, Natalie Landman, Chyuan-Sheng Lin, Min Suk Kang, Gina M. Finan, Lydia S. Park, Ann Z. Moore, Tae-Wan Kim, Jeremy C. Hwang
Publikováno v:
Chemistry & Biology. 20:956-967
Summary Given the complex nature of Alzheimer's disease (AD), a cell-based model that recapitulates the physiological properties of the target neuronal population would be extremely valuable for discovering improved drug candidates and chemical probe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc13d101c52d8eaaff5a3e8d5651f016
https://doi.org/10.1016/j.chembiol.2013.06.005
https://doi.org/10.1016/j.chembiol.2013.06.005
Autor:
Amy M. Matteini, Josef Coresh, Megan L. Grove, Jeremy D. Walston, Eric Boerwinkle, Dan E. Arking, Paulo H M Chaves, Foram N. Ashar, Karen Bandeen-Roche, Anna Moes, Ann Z. Moore, Anne B. Newman
Publikováno v:
Journal of molecular medicine (Berlin, Germany). 93(2)
Mitochondrial function is altered with age and variants in mitochondrial DNA (mtDNA) modulate risk for several age-related disease states. However, the association of mtDNA copy number, a readily available marker which reflects mitochondrial depletio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1393e3a4d84d179af1dbf8a4eaf9ae
https://pubmed.ncbi.nlm.nih.gov/25471480
https://pubmed.ncbi.nlm.nih.gov/25471480
Autor:
Sergey V. Voronov, Agniezka Staniszewski, Hong Zhang, Diego E. Berman, Ottavio Arancio, Claudia Dall'Armi, Tae-Wan Kim, Ann Z. Moore, Laura Beth J. McIntire, Gilbert Di Paolo
Publikováno v:
Nature neuroscience. 11(5)
Synaptic dysfunction caused by oligomeric assemblies of amyloid-beta peptide (Abeta) has been linked to cognitive deficits in Alzheimer's disease. Here we found that incubation of primary cortical neurons with oligomeric Abeta decreases the level of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::602408ea6a65eaf940647442f8eab037
https://pubmed.ncbi.nlm.nih.gov/18391946
https://pubmed.ncbi.nlm.nih.gov/18391946