Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ann Seifried"'
Autor:
Lenora W M Loo, Iona Cheng, Maarit Tiirikainen, Annette Lum-Jones, Ann Seifried, Lucas M Dunklee, James M Church, Robert Gryfe, Daniel J Weisenberger, Robert W Haile, Steven Gallinger, David J Duggan, Stephen N Thibodeau, Graham Casey, Loïc Le Marchand
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30477 (2012)
Genome-wide association studies (GWAS) have identified 19 risk variants associated with colorectal cancer. As most of these risk variants reside outside the coding regions of genes, we conducted cis-expression quantitative trait loci (cis-eQTL) analy
Externí odkaz:
https://doaj.org/article/c45c2221da0b463781a3a17748a5b6c7
Autor:
Lenora W. M. Loo, Robert W. Haile, James M. Church, Daniel J. Weisenberger, Stephen N. Thibodeau, David Duggan, Robert Gryfe, Steven Gallinger, Annette Lum-Jones, Graham Casey, Maarit Tiirikainen, Iona Cheng, Ann Seifried, Loic Le Marchand, Noralane M. Lindor
Publikováno v:
Genes, Chromosomes and Cancer. 52:450-466
Microsatellite stable (MSS), CpG island methylator phenotype (CIMP)-negative colorectal tumors, the most prevalent molecular subtype of colorectal cancer, are associated with extensive copy number alteration (CNA) events and aneuploidy. We report on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c774564462428a67b07c2b0d4dc479a7
https://doi.org/10.1002/gcc.22043
https://doi.org/10.1002/gcc.22043
Autor:
Loic Le Marchand, Lynne R. Wilkens, Ann Seifried, Timothy A. Donlon, Laurence N. Kolonel, Jean H. Hankin
Publikováno v:
Cancer Causes and Control. 13:239-248
Objective: This population-based case–control study was designed to investigate the interrelationships between polymorphisms in the methylenetetrahydrofolate (MTHFR C677T and A1298C) gene and other genes (MTR A2756G; MTRR A66G and CBS 844ins68), in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bded13b63036d243bc6860fa94f9d0af
https://doi.org/10.1023/a:1015057614870
https://doi.org/10.1023/a:1015057614870
Autor:
Robert Gryfe, Iona Cheng, Maarit Tiirikainen, Lucas M. Dunklee, Lenora W. M. Loo, Steven Gallinger, Robert W. Haile, Graham Casey, James M. Church, Daniel J. Weisenberger, Annette Lum-Jones, Stephen N. Thibodeau, Loic Le Marchand, Ann Seifried, David Duggan
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30477 (2012)
PLoS ONE
PLoS ONE
Genome-wide association studies (GWAS) have identified 19 risk variants associated with colorectal cancer. As most of these risk variants reside outside the coding regions of genes, we conducted cis-expression quantitative trait loci (cis-eQTL) analy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0017411456a75482481f1ea3728fe757
http://europepmc.org/articles/PMC3281844?pdf=render
http://europepmc.org/articles/PMC3281844?pdf=render
Autor:
Rachel Novotny, Thomas Ernst, Ann Seifried, Loic Le Marchand, Laurence N. Kolonel, Steven Buchthal, Linda Chang, Unhee Lim, Iona Cheng, Annette Lum-Jones, Cheryl L. Albright, Lynne R. Wilkens
Publikováno v:
Journal of the Academy of Nutrition and Dietetics. 112(7)
Genome-wide association studies have identified common genetic variants that can contribute specifically to the risk of abdominal adiposity, as measured by waist circumference or waist-to-hip ratio. However, it is unknown whether these genetic risk f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03e11bfb097ef3ac0fc8ed2d3c24db41
https://pubmed.ncbi.nlm.nih.gov/22889634
https://pubmed.ncbi.nlm.nih.gov/22889634
Autor:
B. E. Henderson, Annette Lum-Jones, Ann Seifried, Christian Caberto, Daniel O. Stram, Unhee Lim, Le Marchand L, L R Wilkens, Maarit Tiirikainen, Kristine R. Monroe, L N Kolonel, Iona Cheng, Christopher A. Haiman, Fredrick R. Schumacher
Background Diabetes has been positively associated with the risk of colorectal cancer. This study investigated whether recently established risk variants for diabetes also have effects on colorectal cancer. Methods 19 single nucleotide repeats (SNPs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::564de10d91c462023eae5e2856f5584f
https://europepmc.org/articles/PMC4332884/
https://europepmc.org/articles/PMC4332884/
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 11(10 Pt 1)
N-Nitroso compounds are suspected colorectal cancer (CRC) carcinogens to which individuals on a diet high in red meat (RM) may be particularly exposed. Many of these compounds undergo alpha-hydroxylation by CYP2E1 to form DNA adducts. The gene coding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::267248d1308d6b7c011e6761b016f0cf
https://pubmed.ncbi.nlm.nih.gov/12376502
https://pubmed.ncbi.nlm.nih.gov/12376502
Autor:
Loïc, Le Marchand, Timothy, Donlon, Jean H, Hankin, Laurence N, Kolonel, Lynne R, Wilkens, Ann, Seifried
Publikováno v:
Cancer causescontrol : CCC. 13(3)
This population-based case-control study was designed to investigate the interrelationships between polymorphisms in the methylenetetrahydrofolate (MTHFR C677T and A1298C) gene and other genes (MTR A2756G; MTRR A66G and CBS 844ins68), intake of B-vit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::df77ab42ac821676969ea4187704dac5
https://pubmed.ncbi.nlm.nih.gov/12020105
https://pubmed.ncbi.nlm.nih.gov/12020105
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 11(4)
Oxidative stress may be one mechanism by which tobacco smoke causes lung cancer. A common oxidative damage to DNA is the highly mutagenic 7,8-dihydro-8-oxoguanine adduct, which can be repaired by 8-oxoguanine glycosylase I (OGG1). A Ser326Cys substit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3d97d4ada372430c223b2f06442276a1
https://pubmed.ncbi.nlm.nih.gov/11927502
https://pubmed.ncbi.nlm.nih.gov/11927502
Autor:
Lynne R. Wilkens, Sabina Rinaldi, Loic Le Marchand, Timothy A. Donlon, Rudolf Kaaks, Ann Seifried
Publikováno v:
Journal of the National Cancer Institute. 94(6)
Background: Growth hormone (GH) may be associated with the development of colorectal tumors directly and/or indirectly via an increased plasma level of insulin-like growth factor-I (IGF-I), which has been associated with colorectal cancer risk. Becau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8590d4bf98d7544c15a39aee6656bc02
https://pubmed.ncbi.nlm.nih.gov/11904318
https://pubmed.ncbi.nlm.nih.gov/11904318