Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Ann Schlesinger"'
Autor:
Thomas Gersdorf, Ann Schlesinger, Vivianna Fang He, Hans Widmer, Dominic Ehrismann, Guido Koch, Georg von Krogh
Publikováno v:
Nature Reviews Drug Discovery. 18:743-744
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ec33b2afa1f66c36fddb26dd336d317
https://doi.org/10.1038/d41573-019-00001-2
https://doi.org/10.1038/d41573-019-00001-2
Publikováno v:
The Journal of Immunology. 170:5203-5209
Purified components from bacteria selectively activate Toll-like receptors (TLR), leading to shared and unique responses in innate immune cells. Whole bacteria contain agonists for multiple TLR and induce a common macrophage activation program of tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca5ca6cff54dcb2e845fc750200805fd
https://doi.org/10.4049/jimmunol.170.10.5203
https://doi.org/10.4049/jimmunol.170.10.5203
Autor:
Dipanjan Chowdhury, Dong Zhang, Judy Lieberman, Ann Schlesinger, Pengcheng Zhu, Denis Martinvalet
Publikováno v:
Blood, Vol. 114, No 6 (2009) pp. 1205-1216
Granzyme A (GzmA) in killer cells induces caspase-independent programmed cell death. In this study, we show that GzmA cleaves the DNA damage sensor poly(adenosine 5′-diphosphate-ribose) polymerase-1 (PARP-1) after Lys498 in its automodification dom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03e212e5bb974c3ad276e13e0b41699a
https://pubmed.ncbi.nlm.nih.gov/19875524
https://pubmed.ncbi.nlm.nih.gov/19875524
Autor:
Pengcheng Zhu, Judy Lieberman, Hanping Feng, Shenghe Cai, Ann Schlesinger, Laura E. Maliszewski, Dong Zhang, Deborah Palliser
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 175(1)
The intracellular bacterium Listeria monocytogenes infects dendritic cells (DC) and other APCs and induces potent cell-mediated protective immunity. However, heat-killed bacteria fail to do so. This study explored whether DC differentially respond to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::724e1a9088e379e323ade1a97ad6b00c
https://pubmed.ncbi.nlm.nih.gov/15972676
https://pubmed.ncbi.nlm.nih.gov/15972676
Autor:
Ezra G. Jennings, Richard A. Young, Gerard J. Nau, Ann Schlesinger, Joan F. L. Richmond, Eric S. Lander
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 99(3)
Understanding the response of innate immune cells to pathogens may provide insights to host defenses and the tactics used by pathogens to circumvent these defenses. We used DNA microarrays to explore the responses of human macrophages to a variety of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::123ce100563bff10dbf20f3dd989802f
https://pubmed.ncbi.nlm.nih.gov/11805289
https://pubmed.ncbi.nlm.nih.gov/11805289
Publikováno v:
Trends in cell biology. 10(1)
Wnt proteins are secreted, cysteine-rich glycoprotein ligands with numerous roles during animal development. Recent studies of endoderm induction during embryogenesis in the nematode Caenorhabditis elegans challenge the prevailing view that Wnt signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::819bc4b1649d994d83800261717c7098
https://pubmed.ncbi.nlm.nih.gov/10603471
https://pubmed.ncbi.nlm.nih.gov/10603471
Publikováno v:
Cell. 90(4)
A polarizing signal induces endoderm production by a 4-cell stage blastomere in C. elegans called EMS. We identified 16 mutations in five genes mom-1 through mom-5 , required for EMS to produce endoderm. mom-1, mom-2 , and mom-3 are required in the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f932a19686c54a568777e89f18c4f48b
https://pubmed.ncbi.nlm.nih.gov/9288737
https://pubmed.ncbi.nlm.nih.gov/9288737
Autor:
Ann Schlesinger
Publikováno v:
Genome Biology. 3:reports4003.1
Genomics is a relatively new field that has arisen from the sequencing of genomes and advances in microarray technology. Until recently, the methods for obtaining and analyzing genome-scale amounts of information were the main research concerns. Talk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56eb813c383aff344327efae8ae24595
https://doi.org/10.1186/gb-2001-3-1-reports4003
https://doi.org/10.1186/gb-2001-3-1-reports4003
Publikováno v:
Scopus-Elsevier
In a four-cell-stage Caenorhabditis elegans embryo, Wnt signaling polarizes an endoderm precursor called EMS. The polarization of this cell orients its mitotic spindle in addition to inducing endodermal fate in one daughter cell. Reducing the functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31bf7045001762fff348642e93b90ad9
http://www.scopus.com/inward/record.url?eid=2-s2.0-0033180094&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0033180094&partnerID=MN8TOARS
Autor:
Banks, Marcus A.
Publikováno v:
Applied Clinical Trials. Nov2021, Vol. 30 Issue 11, p12-15. 4p.