Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ann Ran-Ran Qin"'
Autor:
Anees M. Dauki, Nishanthan Rajakumaraswamy, Torsten Trowe, Winnie Weng, Kai‐Wen Lin, Emon Elboudjwarej, Ann Ran‐Ran Qin, Christian Schwabe, Michelle R. Kuhne, Ahmed A. Othman
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 8, Pp n/a-n/a (2024)
Abstract Conventional dendritic cells subtype 1 (cDC1) play a vital role in the priming and expansion of tumor‐specific CD8+ T cells and their recruitment to tumor microenvironment. However, cDC1s are often underrepresented in the microenvironment.
Externí odkaz:
https://doaj.org/article/2bd895fe10a44c81a916b61086127b4e
Autor:
Anita Mathias, Carine Beysen, Brian Kirby, Mun Sang Yue, Robert P. Myers, Kimberly L Garrison, Brian P. Kearney, Justin D. Lutz, Ann Ran-Ran Qin, Lorraine Ampaw
Publikováno v:
Clinical pharmacology and therapeutics. 109(5)
Firsocostat (FIR: previously GS-0976), a highly sensitive OATP substrate, reduces hepatic de novo lipogenesis (DNL) by inhibiting acetyl-CoA carboxylases (ACC). Measuring the pharmacodynamic (PD) efficacy of FIR on DNL provides a unique opportunity t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df2523c8d25ad94762814fe0dd50141d
https://pubmed.ncbi.nlm.nih.gov/33141923
https://pubmed.ncbi.nlm.nih.gov/33141923
Autor:
Bob Scott, Mona Kotecha, Ann Ran-Ran Qin, Florence Namour, Hao Zheng, Shringi Sharma, Yan Xin, Kacey Anderson, Jennifer Cuvin
Publikováno v:
Clinical pharmacology in drug development. 8(5)
Filgotinib is a potent, selective Janus kinase-1 inhibitor being developed to treat chronic inflammatory diseases. This phase 1 study in healthy subjects evaluated the relative bioavailability of filgotinib maleate tablets versus the reference tablet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c7beda6046d3abc225c30873983a014
https://pubmed.ncbi.nlm.nih.gov/30768860
https://pubmed.ncbi.nlm.nih.gov/30768860
Publikováno v:
Bioanalysis. 7:1069-1079
Background: In early drug-discovery research, traditional techniques to analyze drug concentrations in tissues for bioanalytical needs include bead beaters and probe homogenization devices, but are not as effective for tough fibrous tissues. To prepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91049e7b3cea6f9618fe12ee8c41c1ac
https://doi.org/10.4155/bio.15.39
https://doi.org/10.4155/bio.15.39
Autor:
Bianca M. Liederer, Brian Dean, Savita Ubhayakar, Sheerin K. Shahidi-Latham, Ann Ran-Ran Qin, Yuzhong Deng, Xiaorong Liang
Publikováno v:
Bioanalysis. 3(17)
Background: In early drug-discovery research, understanding the tissue distribution of drug at the site of action can help to predict the toxicity, efficacy and exposure level of the drug. The bottleneck of tissue analysis by LC–MS/MS is the time-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a40d2f60454bc909cd4de800f0fc326
https://pubmed.ncbi.nlm.nih.gov/21899502
https://pubmed.ncbi.nlm.nih.gov/21899502