Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Ann R. Hunt"'
Autor:
Rachel H. Fong, Benjamin J. Doranz, John T. Roehrig, Susan L. Bennett, Amanda E. Calvert, Ann R. Hunt, Carol D. Blair
Publikováno v:
Virology
Eastern equine encephalitis virus (EEEV), western equine encephalitis virus (WEEV) and Venezuelan equine encephalitis virus (VEEV) can cause fatal encephalitis in humans and equids. Some MAbs to the E1 glycoprotein are known to be cross-reactive, wea
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 4, Iss 7, p e739 (2010)
Venezuelan equine encephalitis virus (VEEV) is responsible for VEE epidemics that occur in South and Central America and the U.S. The VEEV envelope contains two glycoproteins E1 (mediates cell membrane fusion) and E2 (binds receptor and elicits virus
Externí odkaz:
https://doaj.org/article/05da1765fd2245db852ae49bd17d2266
Publikováno v:
Journal of General Virology. 87:2467-2476
A humanized monoclonal antibody (mAb) has been developed and its potential to protect from or cure a Venezuelan equine encephalomyelitis virus (VEEV) infection was evaluated. The VEEV-neutralizing, protective murine mAb 3B4C-4 was humanized using com
Publikováno v:
Annals of the New York Academy of Sciences. 951:286-297
The outbreak of West Nile (WN) encephalitis in the United States has rekindled interest in developing direct methods for prevention and control of human flaviviral infections. Although equine WN vaccines are currently being developed, a WN vaccine fo
Publikováno v:
Annals of the New York Academy of Sciences. 951:272-285
The use of DNA-based vaccines is a novel and promising immunization approach for the development of flavivirus vaccines. This approach has been attempted in vaccine development for various virus species, including St. Louis encephalitis, Russian spri
Autor:
Gwong-Jen J. Chang, Jennifer Squires, Katharine E. Volpe, Ann R. Hunt, John T. Roehrig, Brent S. Davis
Publikováno v:
Journal of Virology. 78:2648-2652
The individual contributions of each of the six conserved disulfide (SS) bonds in the dengue 2 virus envelope (E) glycoprotein (strain 16681) to epitope expression was determined by measuring the reactivities of a panel of well-defined monoclonal ant
Autor:
Kristy L. Gottfried, Harry M. Savage, John T. Roehrig, Amy J. Kerst, Ann R. Hunt, Roger S. Nasci, Kristen L. Burkhalter, Nicholas A. Panella, Roy A. Hall
Publikováno v:
Journal of Clinical Microbiology. 40:2023-2030
An antigen capture immunoassay to detect West Nile (WN) virus antigen in infected mosquitoes and avian tissues has been developed. With this assay purified WN virus was detected at a concentration of 32 pg/0.1 ml, and antigen in infected suckling mou
Publikováno v:
Journal of Virology. 74:4244-4252
Plasmid vectors containing Japanese encephalitis virus (JEV) premembrane (prM) and envelope (E) genes were constructed that expressed prM and E proteins under the control of a cytomegalovirus immediate-early gene promoter. COS-1 cells transformed wit
Autor:
Natth Bhamarapravati, Duane J. Gubler, Siritorn Butrapet, Claire Y.-H. Huang, Gwong-Jen J. Chang, Ann R. Hunt, Richard M. Kinney, Dennis J. Pierro
Publikováno v:
Journal of Virology. 74:3020-3028
We constructed chimeric dengue type 2/type 1 (DEN-2/DEN-1) viruses containing the nonstructural genes of DEN-2 16681 virus or its vaccine derivative, strain PDK-53, and the structural genes (encoding capsid protein, premembrane protein, and envelope
Autor:
Carol D. Blair, Ann R. Hunt, John T. Roehrig, Richard A. Bowen, Shana Frederickson, Toshiaki Maruyama
Publikováno v:
Virology. 414(2)
We recently described a Venezuelan equine encephalitis virus (VEEV)-specific human monoclonal antibody (MAb), F5 nIgG, that recognizes a new neutralization epitope on the VEEV E2 envelope glycoprotein. In this study, we investigated the ability of F5