Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ann Palladino"'
Autor:
Fanying Tang, Duo Xu, Shangqian Wang, Chen Khuan Wong, Alexander Martinez-Fundichely, Cindy J. Lee, Sandra Cohen, Jane Park, Corinne E. Hill, Kenneth Eng, Rohan Bareja, Teng Han, Eric Minwei Liu, Ann Palladino, Wei Di, Dong Gao, Wassim Abida, Shaham Beg, Loredana Puca, Maximiliano Meneses, Elisa de Stanchina, Michael F. Berger, Anuradha Gopalan, Lukas E. Dow, Juan Miguel Mosquera, Himisha Beltran, Cora N. Sternberg, Ping Chi, Howard I. Scher, Andrea Sboner, Yu Chen, Ekta Khurana
Publikováno v:
Cancer Research. 83:NG10-NG10
Untreated prostate cancers rely on androgen receptor (AR) signaling for growth and survival, forming the basis for the initial efficacy of androgen deprivation therapy (ADT). Yet the disease can relapse and progress to a lethal stage termed castratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80219bf2cd05e471fc65067159aa6b36
https://doi.org/10.1158/1538-7445.am2023-ng10
https://doi.org/10.1158/1538-7445.am2023-ng10
Publikováno v:
Cancer Research. 83:2034-2034
Regulatory networks containing enhancer to gene edges define cellular state and their rewiring is a hallmark of cancer. While efforts, such as ENCODE, have revealed these networks for reference tissues and cell-lines by integrating multi-omics data,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9f092eb0bb598c6fe3207b4f5703dbb
https://doi.org/10.1158/1538-7445.am2023-2034
https://doi.org/10.1158/1538-7445.am2023-2034
Autor:
Fanying Tang, Duo Xu, Shangqian Wang, Chen Khuan Wong, Alexander Martinez-Fundichely, Cindy J. Lee, Sandra Cohen, Jane Park, Corinne E. Hill, Kenneth Eng, Rohan Bareja, Teng Han, Eric Minwei Liu, Ann Palladino, Wei Di, Dong Gao, Wassim Abida, Shaham Beg, Loredana Puca, Maximiliano Meneses, Elisa de Stanchina, Michael F. Berger, Anuradha Gopalan, Lukas E. Dow, Juan Miguel Mosquera, Himisha Beltran, Cora N. Sternberg, Ping Chi, Howard I. Scher, Andrea Sboner, Yu Chen, Ekta Khurana
Publikováno v:
Science
In castration-resistant prostate cancer (CRPC), the loss of androgen receptor (AR) dependence leads to clinically aggressive tumors with few therapeutic options. We used ATAC-seq (assay for transposase-accessible chromatin sequencing), RNA-seq, and D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca5dae8949b40ebc59f4303ca93ab2e3
https://doi.org/10.1126/science.abe1505
https://doi.org/10.1126/science.abe1505
Regulatory networks containing enhancer to gene edges define cellular state and their rewiring is a hallmark of cancer. While efforts, such as ENCODE, have revealed these networks for reference tissues and cell-lines by integrating multi-omics data,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c90f1f945b5890c94aa4b953064e38a
https://doi.org/10.1101/2021.11.16.468857
https://doi.org/10.1101/2021.11.16.468857
Autor:
Fanying Tang, Duo Xu, Shangqian Wang, Chen Khuan Wong, Alexander Martinez-Fundichely, Cindy Lee, Sandra Cohen, Jane Park, Corinne Hill, Kenneth Eng, Rohan Bareja, Teng Han, Eric Minwei Liu, Ann Palladino, Wei Di, Dong Gao, Wassim Abida, Shaham Beg, Loredana Puca, Maximiliano Meneses, Elisa De Stanchina, Michael Berger, Anuradha Gopalan, Lukas Dow, Juan Miguel Mosquera, Himisha Beltran, Cora Sternberg, Ping Chi, Howard Scher, Andrea Sboner, Yu Chen, Ekta Khurana
Publikováno v:
Cancer Research. 82:B026-B026
In castration-resistant prostate cancer (CRPC), the loss of androgen receptor (AR) dependence leads to clinically aggressive tumors with few therapeutic options. We used ATAC-seq (assay for transposase-accessible chromatin sequencing), RNA-seq, and D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fc75e60d68175730246f035ff095a6e
https://doi.org/10.1158/1538-7445.cancepi22-b026
https://doi.org/10.1158/1538-7445.cancepi22-b026
Autor:
Eric Minwei Liu, Anuradha Gopalan, Ping Chi, Cindy Lee, Ann Palladino, Yu Chen, Sandra Cohen, Lukas E. Dow, Himisha Beltran, Ekta Khurana, Corinne E. Hill, Kenneth Eng, Shangqian Wang, Juan Miguel Mosquera, Shaham Beg, Teng Han, Loredana Puca, Jane Park, Michael F. Berger, Chen Khuan Wong, Wassim Abida, Rohan Bareja, Howard I. Scher, Andrea Sboner, Dong Gao, Wei Di, Cora N. Sternberg, Fanying Tang
In castration-resistant prostate cancer (CRPC), the loss of androgen receptor (AR)-dependence due to lineage plasticity, which has become more prevalent, leads to clinically highly aggressive tumors with few therapeutic options and is mechanistically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43b82bf79f77e811c601375537976589
https://doi.org/10.1101/2020.10.26.355925
https://doi.org/10.1101/2020.10.26.355925
Publikováno v:
Cancer Research. 81:2034-2034
Epigenomic alterations at regulatory elements have been implicated in cancer tumorigenesis. As a hallmark for epigenetic changes, chromatin accessibility profiles are generated for cancer patients. However, not all accessible regions are active regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f5598d59fb01f53ea7c732e8838cbb7
https://doi.org/10.1158/1538-7445.am2021-2034
https://doi.org/10.1158/1538-7445.am2021-2034