Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Ann Orr"'
Autor:
Eui Tae Kim, Ann Orr, Alexander M. Price, Emigdio D. Reyes, Chris Boutell, Joseph M Dybas, Matthew D. Weitzman, Lisa N. Akhtar, Benjamin A. Garcia, Katarzyna Kulej
Publikováno v:
Nature microbiology
Intrinsic antiviral host factors confer cellular defence by limiting virus replication and are often counteracted by viral countermeasures. We reasoned that host factors that inhibit viral gene expression could be identified by determining proteins b
Autor:
Angela Henderson, Elizabeth Irvine, Eleanor Binnie-McLeod, Fiona Smith, Mark Higgins, Fiona Clark, Karen Lee, Ann Orr, Joanne Spence
Publikováno v:
J Infect Prev
Background: The World Health Organization have designed the fifth of their ‘5 moments’ for hand hygiene to account for microbial transfer from patients to equipment in a narrow area around that patient, known as the patient zone. The study was pr
Autor:
William C. Bowen, George K. Michalopoulos, Jianhua Luo, Vasiliki Gkretsi, Udayan Apte, Wendy M. Mars, Ann Orr, Chuanyue Wu, Satdarshan P.S. Monga, Shashikiran Donthamsetty
Publikováno v:
Hepatology. 50:844-851
Following liver regeneration after partial hepatectomy, liver grows back precisely to its original mass and does not exceed it. The mechanism regulating this "hepatostat" is not clear and no exceptions have been found to date. Although pathways initi
Publikováno v:
Fractals. 16:333-349
Ultrasonic transducers composed of a periodic piezoelectric composite are generally accepted as the design of choice in many applications. Their architecture is normally very regular and this is due to manufacturing constraints rather than performanc
Autor:
Yan P. Yu, Udayan Apte, Yu Yang, René St.-Arnaud, Chuanyue Wu, Klaus H. Kaestner, Vasiliki Gkretsi, Wendy M. Mars, Shoukat Dedhar, George K. Michalopoulos, Jianhua Luo, William C. Bowen, Ann Orr
Publikováno v:
Hepatology. 48:1932-1941
Liver supports multiple homeostatic functions of the body and maintains an appropriate size for the needs of the organism by combining (as needed) cell proliferation (to restore or increase weight) and apoptosis (to decrease weight, or in response to
Autor:
Duane R. Pilch, Emmy P. Rogakou, Christophe E. Redon, Noel F. Lowndes, Ann Orr, William M. Bonner
Publikováno v:
EMBO reports. 4:678-684
Cells maintain genomic stability by the coordination of DNA-damage repair and cell-cycle checkpoint control. In replicating cells, DNA damage usually activates intra-S-phase checkpoint controls, which are characterized by delayed S-phase progression
Autor:
Terrence R. Burke, Nouri Neamati, Yves Pommier, Young K. Lee, Ryan D. Brown, Xuechun Zhang, Noel Whitaker, Ann Orr
Publikováno v:
Bioorganic & Medicinal Chemistry. 9:1649-1657
Integrase is an enzyme found in human immunodeficiency virus, which is required for the viral life cycle, yet has no human cellular homologue. For this reason, HIV integrase (IN) has become an important target for the development of new AIDS therapeu
Autor:
Lynne Anderson, Marc C. Nicklaus, B. Yves Pommier, James A. Kelley, Alexander D. MacKerell, Nouri Neamati, Ann Orr, Joseph J. Barchi, Chen I-Jen
Publikováno v:
Bioorganic & Medicinal Chemistry. 8:2385-2398
Integration of viral DNA into the host cell genome is a critical step in the life cycle of HIV. This essential reaction is catalyzed by integrase (IN) through two steps, 3'-processing and DNA strand transfer. Integrase is an attractive target for dru