Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ann M. Gregus"'
Autor:
Laura B. Murdaugh, Cristina Miliano, Irene Chen, Christine L. Faunce, Luis A. Natividad, Ann M. Gregus, Matthew W. Buczynski
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Nicotine use is a leading cause of preventable deaths worldwide, and most of those who attempt to quit will relapse. While electronic cigarettes and other electronic nicotine delivery systems (ENDS) were presented as a safer alternative to t
Externí odkaz:
https://doaj.org/article/244ee4a574554aa3ae0ca3847aeec181
Autor:
Irene Chen, Laura B. Murdaugh, Cristina Miliano, Yuyang Dong, Ann M. Gregus, Matthew W. Buczynski
Publikováno v:
Neurobiology of Pain, Vol 14, Iss , Pp 100135- (2023)
N-acyl-ethanolamine (NAEs) serve as key endogenous lipid mediators as revealed by manipulation of fatty acid amide hydrolase (FAAH), the primary enzyme responsible for metabolizing NAEs. Preclinical studies focused on FAAH or NAE receptors indicate a
Externí odkaz:
https://doaj.org/article/cefaeb0c57eb4b20a612384a6082ac3d
Autor:
Juliana M. Navia-Pelaez, Julia Borges Paes Lemes, Leonardo Gonzalez, Lauriane Delay, Luciano dos Santos Aggum Capettini, Jenny W. Lu, Gilson Gonçalves Dos Santos, Ann M. Gregus, Patrick M. Dougherty, Tony L. Yaksh, Yury I. Miller
Publikováno v:
Pain. 164:e274-e285
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6064df68a78d5e6b2442b8e2413373bf
https://doi.org/10.1097/j.pain.0000000000002834
https://doi.org/10.1097/j.pain.0000000000002834
Autor:
Amanda Laque, Grant E. Wagner, Alessandra Matzeu, Genna L. De Ness, Tony M. Kerr, Ayla M. Carroll, Giordano Guglielmo, Hermina Nedelescu, Matthew W. Buczynski, Ann M. Gregus, Thomas C. Jhou, Eric P. Zorrilla, Remi Martin‐Fardon, Eisuke Koya, Robert C. Ritter, Friedbert Weiss, Nobuyoshi Suto
Publikováno v:
Br J Pharmacol
Background and Purpose\ud “Food addiction” is the subject of intense public and research interest. However, this nosology based on neurobehavioral similarities among obese individuals and patients with eating disorders and drug addiction remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73fd4fda2a995023f61373f4e734def9
https://doi.org/10.1111/bph.15797
https://doi.org/10.1111/bph.15797
Autor:
Katelyn A. Bustin, Kyosuke Shishikura, Irene Chen, Zongtao Lin, Nate McKnight, Yuxuan Chang, Xie Wang, Jing Jing Li, Eric Arellano, Liming Pei, Paul D. Morton, Ann M. Gregus, Matthew W. Buczynski, Megan L. Matthews
Publikováno v:
bioRxiv
Chemical platforms that facilitate both the identification and elucidation of new areas for therapeutic development are necessary but lacking. Activity-based protein profiling (ABPP) leverages active site-directed chemical probes as target discovery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45d12551e345d1eaed3b2bb9aa23fd98
https://europepmc.org/articles/PMC9915563/
https://europepmc.org/articles/PMC9915563/
Publikováno v:
Pain
Pain is the primary motivation for seeking medical care. Although pain may subside as inflammation resolves or an injury heals, it is increasingly evident that persistency of the pain state can occur with significant regularity. Chronic pain requires
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de01ba2f71c2431544000f20272eeaac
https://doi.org/10.1097/j.pain.0000000000002215
https://doi.org/10.1097/j.pain.0000000000002215
Autor:
William H. Parsons, Megan L. Matthews, Zongtao Lin, Eric S. Witze, Ann M. Gregus, Nancy Schek, Radu M. Suciu, Erika J. Olson, Mina Ahmadi, Katelyn A. Bustin, Xie Wang, Matthew W. Buczynski, Kai Hu, Lin He, Paul D. Morton
Known chemoproteomic probes generally use warheads that tag a single type of amino acid or modified form thereof to identify cases in which its hyper-reactivity underpins function. Much important biochemistry derives from electron-poor enzyme cofacto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cc363bc1007f4bcb6e7aa57762843d6
https://doi.org/10.1101/2020.06.17.154864
https://doi.org/10.1101/2020.06.17.154864
Autor:
Matthew W. Buczynski, Ann M. Gregus
Publikováno v:
Adv Exp Med Biol
Druggable Lipid Signaling Pathways ISBN: 9783030506209
Druggable Lipid Signaling Pathways ISBN: 9783030506209
Cannabis and cannabinoid-based extracts have long been utilized for their perceived therapeutic value, and support for the legalization of cannabis for medicinal purposes continues to increase worldwide. Since the discovery of Δ(9)-tetrahydrocannabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92c51905b5193e68600895d95991c7c6
https://europepmc.org/articles/PMC7811746/
https://europepmc.org/articles/PMC7811746/
Autor:
David J. Maloney, Tony L. Yaksh, Ganesha Rai, Qinghao Xu, Matthew W. Buczynski, Spencer C. Wei, Ann M. Gregus, Anton Simeonov, Paul C. Norris, Darren S. Dumlao, Edward A. Dennis, Ajit Jadhav, Bethany Fitzsimmons
Publikováno v:
Pain, vol 159, iss 12
Although nonsteroidal anti-inflammatory drugs are the first line of therapeutics for the treatment of mild to moderate somatic pain, they are not generally considered to be effective for neuropathic pain. In the current study, direct activation of sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388f2852143f25b37c08eae33fba3510
https://doi.org/10.1097/j.pain.0000000000001373
https://doi.org/10.1097/j.pain.0000000000001373
Autor:
Emma R. Gnatowski, Malissa M. Reyes, Matthew W. Buczynski, E. Reilly Scott, Laura B. Murdaugh, Cristina Miliano, Megan S. Anderson, Christine L. Faunce, Ann M. Gregus
Publikováno v:
J Neurosci Methods
Smoking tobacco products is the leading cause of preventable death worldwide. Coordinated efforts have successfully reduced tobacco cigarette smoking in the United States; however, electronic cigarettes (e-cigarette) and other electronic nicotine del
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b751485f931d832b6724104fa258174
https://pubmed.ncbi.nlm.nih.gov/31614162
https://pubmed.ncbi.nlm.nih.gov/31614162