Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ann M. Detmer"'
Autor:
Natalya Levenkova, Pascal Bouffard, Roger W. Wiseman, Ann M. Detmer, Benjamin N. Bimber, David H. O’Connor, Chris L. Wright, Claire E. O’Leary, Jennifer J. Tuscher, Cynthia L Turcotte, Julie A. Karl, Timothy T. Harkins, Simon M. Lank, Edward S. Szekeres
Publikováno v:
Nature Medicine. 15:1322-1326
Major histocompatibility complex (MHC) genetics dictate adaptive cellular immune responses, making robust MHC genotyping methods essential for studies of infectious disease, vaccine development, and transplantation. Nonhuman primates provide essentia
Autor:
Shelby L. O’Connor, Alex J. Blasky, Kevin J. Campbell, Benjamin N. Bimber, Julie A. Karl, Roger W. Wiseman, Ann M. Detmer, Austin L. Hughes, David H. O’Connor
Publikováno v:
Immunogenetics. 61:177-187
Cynomolgus macaques (Macaca fascicularis) provide increasingly common models for infectious disease research. Several geographically distinct populations of these macaques from Southeast Asia and the Indian Ocean island of Mauritius are available for
Autor:
Jennifer J. Tuscher, Thomas C. Friedrich, Jennifer J. Lhost, Julie A. Karl, David H. O’Connor, Nicola J. Rose, Austin L. Hughes, Ann M. Detmer, Randall C. Johnson, Benjamin J. Burwitz, Justin M. Greene, Caitlin E. MacNair, Ericka A. Becker, Edward T. Mee, Benjamin N. Bimber, Roger W. Wiseman, Simon M. Lank, Shelby L. O’Connor, Mary Carrington, Ronald C. Desrosiers
Publikováno v:
Science translational medicine. 2(22)
The importance of a broad CD8 T lymphocyte (CD8-TL) immune response to HIV is unknown. Ex vivo measurements of immunological activity directed at a limited number of defined epitopes provide an incomplete portrait of the actual immune response. We ex
Autor:
Simon M. Lank, David H. O’Connor, David Price, Austin L. Hughes, Emma Gostick, Shelby L. O’Connor, Benjamin N. Bimber, Ann M. Detmer, Benjamin J. Burwitz
Publikováno v:
Journal of virology. 83(16)
Human and simian immunodeficiency viruses (HIV/SIV) exhibit enormous sequence heterogeneity within each infected host. Here, we use ultradeep pyrosequencing to create a comprehensive picture of CD8 + T-lymphocyte (CD8-TL) escape in SIV-infected macaq
Autor:
Wilfried Bardet, Jennifer J. Lhost, Justin M. Greene, William H. Hildebrand, Roger W. Wiseman, Lyle T. Wallace, Benjamin N. Bimber, Shari M. Piaskowski, Benjamin J. Burwitz, John T. Loffredo, David H. O’Connor, Shelby L. O’Connor, Richard Rudersdorf, Julie A. Karl, Ann M. Detmer, Daryl Cox, Chad J. Pendley
Publikováno v:
Journal of virology. 83(12)
Vaccines that elicit CD8+T-cell responses are routinely tested for immunogenicity in nonhuman primates before advancement to clinical trials. Unfortunately, the magnitude and specificity of vaccine-elicited T-cell responses are variable in currently
Autor:
Ann M. Detmer, Jeremy P. Loenneke, Takashi Abe, J. Grant Mouser, Daeyeol Kim, Kirsten M. Allen, Robert S. Thiebaud, Michael G. Bemben
Publikováno v:
Medicine & Science in Sports & Exercise. 47:549
Autor:
Ann M. Detmer, John W. Farrell, Gregory S. Cantrell, Daniel J. Larson, David J. Lantis, Rebecca D. Larson, Jason A. Campbell, Shelby R. Shipman, Michael G. Bemben, Monica A. Barton
Publikováno v:
Medicine & Science in Sports & Exercise. 47:947
Autor:
J. Grant Mouser, Jeremy P. Loenneke, Kirsten M. Allen, Daeyeol Kim, Robert S. Thiebaud, Ann M. Detmer, Takashi Abe, Michael G. Bemben
Publikováno v:
Medicine & Science in Sports & Exercise. 46:882
Autor:
Austin L. Hughes, Simon M. Lank, Emma Gostick, Benjamin N. Bimber, David H. O’Connor, Benjamin J. Burwitz, Shelby L. O’Connor, David Price, Ann M. Detmer
Publikováno v:
Retrovirology
Retrovirology, Vol 6, Iss Suppl 3, p P386 (2009)
Retrovirology, Vol 6, Iss Suppl 3, p P386 (2009)
Background A complex population of viral variants exists within each individual infected with immunodeficiency virus. Deciphering the breadth and frequency of accruing viral mutations provides insight into immune responses, drug resistance, and poten