Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Ann M Simpson"'
Publikováno v:
Biomarker Insights, Vol 13 (2018)
Atherosclerosis is the underlying cause of most myocardial infarction (MI) and ischaemic stroke episodes. An early sign of atherosclerosis is hypertrophy of the arterial wall. It is known that increased intima media thickness (IMT) is a non-invasive
Externí odkaz:
https://doaj.org/article/c105c8de65ad40ce9d8123b79bce49dc
Publikováno v:
Biomarker Insights, Vol 13 (2018)
Background: Heart rate variability (HRV) is a non-invasive measure of the function of the autonomic nervous system, and its dynamic nature may provide a means through which stroke and its associated complications may be predicted, monitored, and mana
Externí odkaz:
https://doaj.org/article/5fb4abaf84ef44e9bd3db462f1301e7e
Autor:
Janet Lawandi, Chang Tao, Binhai Ren, Paul Williams, Dora Ling, M Anne Swan, Najah T Nassif, Fraser R Torpy, Bronwyn A O'Brien, Ann M Simpson
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 2, Iss , Pp - (2015)
As an alternative to the transplantation of islets, a human liver cell line has been genetically engineered to reverse type 1 diabetes (TID). The initial liver cell line (Huh7ins) commenced secretion of insulin in response to a glucose concentration
Externí odkaz:
https://doaj.org/article/d6ed86ffb2e34f5db83a856612ee11ab
Autor:
Maria E Lund, Bronwyn A O'Brien, Andrew T Hutchinson, Mark W Robinson, Ann M Simpson, John P Dalton, Sheila Donnelly
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86289 (2014)
Infections with helminth parasites prevent/attenuate auto-inflammatory disease. Here we show that molecules secreted by a helminth parasite could prevent Type 1 Diabetes (T1D) in nonobese diabetic (NOD) mice. When delivered at 4 weeks of age (coincid
Externí odkaz:
https://doaj.org/article/caff9c70f6774635b63afd1dd98d17d6
Publikováno v:
International Journal of Translational Medicine, Vol 3, Iss 3, Pp 374-388 (2023)
Type 1 Diabetes (T1D) is a chronic metabolic disorder for which current treatments are unable to prevent the onset of complications. Previously, we used an adeno-associated viral vector (AAV8) to deliver furin-cleavable human insulin (INS-FUR) to the
Externí odkaz:
https://doaj.org/article/a61c1240d3e442af9001404749933bba
Autor:
Alka Rachel John, Avinash K. Singh, Tien-Thong Nguyen Do, Ami Eidels, Eugene Nalivaiko, Alireza Mazloumi Gavgani, Scott Brown, Murray Bennett, Sara Lal, Ann M. Simpson, Sylvia M. Gustin, Kay Double, Frederick Rohan Walker, Sabina Kleitman, John Morley, Chin-Teng Lin
Publikováno v:
IEEE Transactions on Neural Systems and Rehabilitation Engineering, Vol 30, Pp 770-781 (2022)
Modern work environments have extensive interactions with technology and greater cognitive complexity of the tasks, which results in human operators experiencing increased mental workload. Air traffic control operators routinely work in such complex
Externí odkaz:
https://doaj.org/article/15309b3093ce4876a1e0a5d38de9da4d
Publikováno v:
Cells, Vol 11, Iss 14, p 2145 (2022)
Type 1 diabetes is a chronic illness in which the native beta (β)-cell population responsible for insulin release has been the subject of autoimmune destruction. This condition requires patients to frequently measure their blood glucose concentratio
Externí odkaz:
https://doaj.org/article/f3d9fb1800984723932c217a39c01e69
Autor:
Wilson K.M. Wong, Mugdha V. Joglekar, Vijit Saini, Guozhi Jiang, Charlotte X. Dong, Alissa Chaitarvornkit, Grzegorz J. Maciag, Dario Gerace, Ryan J. Farr, Sarang N. Satoor, Subhshri Sahu, Tejaswini Sharangdhar, Asma S. Ahmed, Yi Vee Chew, David Liuwantara, Benjamin Heng, Chai K. Lim, Julie Hunter, Andrzej S. Januszewski, Anja E. Sørensen, Ammira S.A. Akil, Jennifer R. Gamble, Thomas Loudovaris, Thomas W. Kay, Helen E. Thomas, Philip J. O'Connell, Gilles J. Guillemin, David Martin, Ann M. Simpson, Wayne J. Hawthorne, Louise T. Dalgaard, Ronald C.W. Ma, Anandwardhan A. Hardikar
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102379- (2021)
Summary: Dicer knockout mouse models demonstrated a key role for microRNAs in pancreatic β-cell function. Studies to identify specific microRNA(s) associated with human (pro-)endocrine gene expression are needed. We profiled microRNAs and key pancre
Externí odkaz:
https://doaj.org/article/016725883f2b42db88e23b368f58c758
Autor:
Ann M. Simpson (Mitchell)
Publikováno v:
Practical Theology. 15:432-444
Autor:
Nhan H.T. Pham, Mugdha V. Joglekar, Wilson K.M. Wong, Najah T. Nassif, Ann M. Simpson, Anandwardhan A. Hardikar
ContextThere is substantial evidence that reduced gut short chain fatty acids (SCFAs) are associated with obesity and type 2 diabetes, although findings from clinical interventions that could increase SCFAs are inconsistent.ObjectiveThis work aimed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c3fea369e210aa8e14925d8638f8614
https://doi.org/10.1101/2022.11.22.22282645
https://doi.org/10.1101/2022.11.22.22282645