Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ann M Joseph"'
Autor:
Peter J. B. Sabatini, Resham Ejaz, Dimitri J. Stavropoulos, Roberto Mendoza-Londono, Ann M. Joseph-George
Publikováno v:
Molecular Cytogenetics, Vol 11, Iss 1, Pp 1-5 (2018)
Abstract Background Complex genomic structural variations, involving chromoanagenesis, have been implicated in multiple congenital anomalies and abnormal neurodevelopment. Familial inheritance of complex chromosomal structural alteration resulting fr
Externí odkaz:
https://doaj.org/article/30439dec26e44dfdb08ade0f42c79039
Hepatitis C Virus (HCV) load in plasma were often below the validated quantitative RT-PCR (RT-qPCR) calibration plot concentrations. In this report, data analysis of RT-PCR amplification plots and calibration plots were done to define the performance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::699252c6e41f37429eed9f861e257dd1
https://doi.org/10.21203/rs.3.rs-1834584/v1
https://doi.org/10.21203/rs.3.rs-1834584/v1
Autor:
Lei Zhou, Wenqing Zhou, Ann M. Joseph, Coco Chu, Gregory G. Putzel, Beibei Fang, Fei Teng, Mengze Lyu, Hiroshi Yano, Katrin I. Andreasson, Eisuke Mekada, Gerard Eberl, Gregory F. Sonnenberg
Publikováno v:
Nat Immunol
Tumor necrosis factor (TNF) drives chronic inflammation and cell death in the intestine, and blocking TNF is a therapeutic approach in inflammatory bowel disease (IBD). Despite this knowledge, the pathways that protect the intestine from TNF are inco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c824738853279cd2351c7774bc2fc8e
https://europepmc.org/articles/PMC8842850/
https://europepmc.org/articles/PMC8842850/
Autor:
Amy M, Tsou, Hiroshi, Yano, Christopher N, Parkhurst, Tanel, Mahlakõiv, Coco, Chu, Wen, Zhang, Zhengxiang, He, Katja J, Jarick, Connie, Zhong, Gregory G, Putzel, Mai, Hatazaki, Ivo C, Lorenz, David, Andrew, Paul, Balderes, Christoph S N, Klose, Sergio A, Lira, Ann M, Joseph
Publikováno v:
Nature. 611(7937)
Emerging studies indicate that cooperation between neurons and immune cells regulates antimicrobial immunity, inflammation and tissue homeostasis. For example, a neuronal rheostat provides excitatory or inhibitory signals that control the functions o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224534bc9007a36cfaa8613bcb9f7458
https://pubmed.ncbi.nlm.nih.gov/36323781
https://pubmed.ncbi.nlm.nih.gov/36323781
Autor:
Jonathan M. Coutinho, Roshni R. Singaraja, Martin Kang, David J. Arenillas, Lisa N. Bertram, Nagat Bissada, Bart Staels, Jean-Charles Fruchart, Catherine Fievet, Ann M. Joseph-George, Wyeth W. Wasserman, Michael R. Hayden
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 6, Pp 1113-1123 (2005)
Humanized mouse models are useful tools to explore the functional and regulatory differences between human and murine orthologous genes. We have combined a bioinformatics approach and an in vivo approach to assess the functional and regulatory differ
Externí odkaz:
https://doaj.org/article/d92660a5138a4dc6b2fd57727cefc16a
Publikováno v:
International Journal of Oncology.
The increased tyrosine kinase activity of nonsmall cell lung cancer (NSCLC)associated epidermal growth factor receptor (EGFR) mutants results in deregulated pathways that contribute to malignant cell survival, tumor progression and metastasis. Pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7ee3e504e9a9cc0b45f2bf3213f92ee
https://doi.org/10.3892/ijo.2020.5112
https://doi.org/10.3892/ijo.2020.5112
Autor:
Wilson W L Sung, S. Mohsen Hosseini, Brett Trost, Stephen W. Scherer, John Wei, James Ellis, Jeffrey R. MacDonald, Sarah Bowdin, Janet A. Buchanan, M. Stephen Meyn, Miriam S. Reuter, Rohan V. Patel, Giovanna Pellecchia, Allison Hazell, Ryan A. Cook, Sergio L. Pereira, Bhooma Thiruvahindrapuram, Jennifer L. Howe, Iris Cohn, Lisa J. Strug, Ryan K. C. Yuen, Peter Pasceri, Yvonne Bombard, Joe Whitney, Hin C. Lee, Tara Paton, Anne S. Bassett, Rosanna Weksberg, Jill Davies, Barbara Kellam, Dimitri J. Stavropoulos, Wei Wei, Christian R. Marshall, Cheryl Shuman, Marc Fiume, Fred W. Keeley, Richard F. Wintle, Matthew R. Hildebrandt, Jo Anne Herbrick, Zhuozhi Wang, Peter N. Ray, Thomas Nalpathamkalam, Ronald D. Cohn, Sherilyn L. Bell, Neal Sondheimer, Daniele Merico, Susan Walker, Ann M. Joseph-George, Melanie M. Mahtani, Asli Romm, Chao Lu, Michael J. Szego, Nasim Monfared
Publikováno v:
Canadian Medical Association Journal. 190:E126-E136
BACKGROUND: The Personal Genome Project Canada is a comprehensive public data resource that integrates whole genome sequencing data and health information. We describe genomic variation identified in the initial recruitment cohort of 56 volunteers. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b2df1093bd60b4a1ff0d0715877c4f3
https://doi.org/10.1503/cmaj.171151
https://doi.org/10.1503/cmaj.171151
Autor:
John B Grigg, Arthi Shanmugavadivu, Tommy Regen, Christopher N Parkhurst, Anees Ahmed, Ann M Joseph, Michael Mazzucco, Gerard Eberl, Timothy Vartanian, Ari Waisman, Gregory F Sonnenberg
Publikováno v:
The Journal of Immunology. 206:13.03-13.03
Pro-inflammatory T cells in the central nervous system (CNS) are causally associated with multiple demyelinating and neurodegenerative diseases, but the pathways controlling these responses remain unclear. Here we define a unique population of group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04ee67c2a8244d249c023af15d53ee61
https://doi.org/10.4049/jimmunol.206.supp.13.03
https://doi.org/10.4049/jimmunol.206.supp.13.03
Autor:
Ebba Alkhunaizi, Ann M. Joseph-George, Fowzan S. Alkuraya, Susan Blaser, Sanjay Kumar Bharti, Mais Hashem, Nicole Martin, Ranad Shaheen, Robert M. Brosh, David Chitayat, Mohammed Al-Owain, Mohammed A. Butt, Ghada M H Abdel-Salam, Karen Chong, Blake C. Papsin, Ruth Godoy
Publikováno v:
American journal of medical genetics. Part A. 176(11)
Warsaw breakage syndrome (WBS) is a recently recognized DDX11-related rare cohesinopathy, characterized by severe prenatal and postnatal growth restriction, microcephaly, developmental delay, cochlear anomalies and sensorineural hearing loss. Only se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bce1018b6dd7460bb63c9a29b97329d9
https://pubmed.ncbi.nlm.nih.gov/30216658
https://pubmed.ncbi.nlm.nih.gov/30216658
Autor:
Stephen W. Scherer, Bhooma Thiruvahindrapuram, Ann M. Joseph-George, Peter Kannu, Emmanuelle Lemyre, Ada Chan, Susan Walker, Mary Shago, Grace Yoon, Janet A. Buchanan, Abdul Noor, Lia D’Abate, Christian R. Marshall, Melissa T. Carter, Sonia Nizard, Mehdi Zarrei, Géraldine Mathonnet, Kristiina Tammimies, Thomas Nalpathamkalam, Ryan K. C. Yuen, Mohammed Uddin, Frédérique Tihy, Daniele Merico, Dimitri J. Stavropoulos, Giovanna Pellecchia, Matthew J. Gazzellone, Erik C. Thorland, Koenraad Devriendt, Marsha Speevak
Publikováno v:
Scientific Reports
A challenge in clinical genomics is to predict whether copy number variation (CNV) affecting a gene or multiple genes will manifest as disease. Increasing recognition of gene dosage effects in neurodevelopmental disorders prompted us to develop a com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a040389d68fcbb851ded76a26a18ca01
https://doi.org/10.1038/srep28663
https://doi.org/10.1038/srep28663