Zobrazeno 1 - 10
of 739
pro vyhledávání: '"Ann M Bode"'
Autor:
Lin Zhao, Xiangying Deng, Yueshuo Li, Jianmin Hu, Longlong Xie, Feng Shi, Min Tang, Ann M Bode, Xin Zhang, Weihua Liao, Ya Cao
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 12, Pp n/a-n/a (2021)
Abstract Adenine nucleotide translocase‐1 (ANT1) is an ADP/ATP transporter protein located in the inner mitochondrial membrane. ANT1 is involved not only in the processes of ADP/ATP exchange but also in the composition of the mitochondrial membrane
Externí odkaz:
https://doaj.org/article/016cf629e56b405bab15badb0df6cbca
Autor:
Olumide Kayode, Zunnan Huang, Alexei S Soares, Thomas R Caulfield, Zigang Dong, Ann M Bode, Evette S Radisky
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176694 (2017)
PRSS3/mesotrypsin is an atypical isoform of trypsin, the upregulation of which has been implicated in promoting tumor progression. To date there are no mesotrypsin-selective pharmacological inhibitors which could serve as tools for deciphering the pa
Externí odkaz:
https://doaj.org/article/8bf9e1a332974705854101e84feec27a
Autor:
Hanyong Chen, Ke Yao, Xiaoyu Chang, Jung-Hyun Shim, Hong-Gyum Kim, Margarita Malakhova, Dong-Joon Kim, Ann M Bode, Zigang Dong
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130049 (2015)
The most active anticancer component in green tea is epigallocatechin-3-gallate (EGCG). Protein interaction with EGCG is a critical step for mediating the effects of EGCG on the regulation of various key molecules involved in signal transduction. By
Externí odkaz:
https://doaj.org/article/237546dfd3834fe691d9896e2234383f
Autor:
Soouk Kang, Jong-Eun Kim, Nu Ry Song, Sung Keun Jung, Mee Hyun Lee, Jun Seong Park, Myeong-Hun Yeom, Ann M Bode, Zigang Dong, Ki Won Lee
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104305 (2014)
Studies have shown that a major metabolite of the red ginseng ginsenoside Rb1, called 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol (GPD), exhibits anticancer properties. However, the chemotherapeutic effects and molecular mechanisms behind GPD acti
Externí odkaz:
https://doaj.org/article/dfe2d2860b8343488479d69238d01f43
Autor:
Yueshuo Li, Chenxing Yang, Longlong Xie, Feng Shi, Min Tang, Xiangjian Luo, Na Liu, Xudong Hu, Yongwei Zhu, Ann M. Bode, Qiang Gao, Jian Zhou, Jia Fan, Xuejun Li, Ya Cao
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Abnormal expression of Cylindromatosis (CYLD), a tumor suppressor molecule, plays an important role in tumor development and treatment. In this work, we found that CYLD binds to class I histone deacetylases (HDAC1 and HDAC2) through its N-te
Externí odkaz:
https://doaj.org/article/f0d88082449b4f8b878e1387a80ca5d1
Autor:
Haitao Li, Feng Zhu, Yanwen Sun, Bing Li, Naomi Oi, Hanyong Chen, Ronald A Lubet, Ann M Bode, Zigang Dong
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76452 (2013)
Recent clinical trials raised concerns regarding the cardiovascular toxicity of selective cyclooxygenase-2 (COX-2) inhibitors. Many active dietary factors are reported to suppress carcinogenesis by targeting COX-2. A major question was accordingly ra
Externí odkaz:
https://doaj.org/article/e5ae3c7251064df2997bdbc8a1fa9fbe
Autor:
Yong-Yeon Cho, Dong Joon Kim, Hye Suk Lee, Chul-Ho Jeong, Eun-Jin Cho, Myong-Ok Kim, Sanguine Byun, Kun-Yeong Lee, Ke Yao, Andria Carper, Alyssa Langfald, Ann M Bode, Zigang Dong
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57172 (2013)
Autophagy is a critical cellular process required for maintaining cellular homeostasis in health and disease states, but the molecular mechanisms and impact of autophagy on cancer is not fully understood. Here, we found that Sox2, a key transcription
Externí odkaz:
https://doaj.org/article/52064fb769c7471494f1219317d4534f
Autor:
Juan Xu, Xiyun Deng, Min Tang, Lili Li, Lanbo Xiao, Lifang Yang, Juanfang Zhong, Ann M Bode, Zigang Dong, Yongguang Tao, Ya Cao
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e56114 (2013)
The latent membrane protein 1 (LMP1), which is encoded by the Epstein-Barr virus (EBV), is an important oncogenic protein that is closely related to carcinogenesis and metastasis of nasopharyngeal carcinoma (NPC), a prevalent cancer in China. We prev
Externí odkaz:
https://doaj.org/article/118ae666979b449ca5bab080072ab133
Autor:
Haidan Liu, Zhi Duan, Hui Zheng, Duosha Hu, Ming Li, Yongguang Tao, Ann M Bode, Zigang Dong, Ya Cao
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32624 (2012)
Accumulating evidence indicates that epithelial cancer cells, including nasopharyngeal carcinoma (NPC) cells, express immunoglobulins (Igs). We previously found that the expression of the kappa light chain protein in NPC cells can be upregulated by t
Externí odkaz:
https://doaj.org/article/9d5dd738877d42189e4667c376c5706d
Autor:
Hanyong Chen, Ke Yao, Janos Nadas, Ann M Bode, Margarita Malakhova, Naomi Oi, Haitao Li, Ronald A Lubet, Zigang Dong
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e38261 (2012)
Plant-based polyphenols (i.e., phytochemicals) have been used as treatments for human ailments for centuries. The mechanisms of action of these plant-derived compounds are now a major area of investigation. Thousands of phytochemicals have been isola
Externí odkaz:
https://doaj.org/article/6b8767255c4f4de8a0f3d80118ce82dd