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pro vyhledávání: '"Ann M Bayly"'
Autor:
Ian Macreadie, Ann M Bayly
Publikováno v:
FEMS Microbiology Letters. 213:189-192
Microbes and plants synthesise folate using a unique biosynthetic pathway that is absent in animals. The end product, tetrahydrofolate, is utilised by all forms of life. In this study, an intermediate in this synthesis, dihydropteroic acid, was found
Publikováno v:
Journal of Immunological Methods. 262:217-227
This protocol describes optimised large-scale bacterial fermentation conditions for recombinant single-chain Fv molecule (scFv) monomers and multimers (diabodies and triabodies). The heat-inducible bacterial secretion vector, pPOW3, utilising the tem
Autor:
Carol Hopkins Sibley, Ian Macreadie, Eleanor G. Hankins, Onisha Patel, Ann M Bayly, Laura A. Castelli, Peter Coloe, Janette Berglez
Publikováno v:
FEMS Microbiology Letters. 204:387-390
Saccharomyces cerevisiae mutants deficient in folate synthesis have been constructed and employed to study the utilisation of exogenous folates in yeast. One mutant specifically lacked dihydropteroate synthase while the second lacked dihydrofolate sy
Autor:
John E. Burns, Barbara E. Power, Peter J. Hudson, Larissa Doughty, Alexander A. Kortt, Deborah Shapira, Andrew M. Scott, Joanne M. Caine, Zhanqi Liu, Ann M Bayly
Publikováno v:
Protein science : a publication of the Protein Society. 12(4)
Single-chain variable fragments (scFvs) of anti-Lewis(y) hu3S193 humanized antibody were constructed by joining the V(H) and V(L) domains with either +2 residues, +1 residue, or by directly linking the domains. In addition two constructs were synthes
Autor:
Ann M Bayly, Ian Macreadie
Publikováno v:
Trends in Parasitology. 18:49-50
Folic acid antagonizes the sulfa drug treatment of malaria. This antagonism has been mimicked in a yeast model system, where the growth inhibition by sulfa drugs can be confounded. In addition, yeast studies show that the inhibition is independent of
Autor:
Power, Barbara E., Doughty, Larissa, Shapira, Deborah R., Burns, John E., Bayly, Ann M., Caine, Joanne M., Liu, Zhanqi, Scott, Andrew M., Hudson, Peter J., Kortt, Alexander A.
Publikováno v:
Protein Science: A Publication of the Protein Society; 2003, Vol. 12 Issue 4, p734-747, 14p