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Akademický článek

Teletherapy to address language disparities in deaf and hard-of-hearing children: study protocol for an inclusive multicentre clinical trial

Autor: Ann Lazar, Kendyl Naugle, Jihyun Stephans, Joy M Kearns, Sarah Coulthurst, Kathleen P Tebb, Dylan K Chan

Publikováno v: BMJ Open, Vol 14, Iss 8 (2024)

Introduction Children who are deaf or hard-of-hearing (DHH) are at risk for speech and language delay. Language outcomes are worse in DHH children from lower socioeconomic backgrounds, due in part to disparities in access to specialised speech-langua

Externí odkaz: https://doaj.org/article/1dbff4e39db04c9db13d494107416214

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Akademický článek

Pragmatic phase II clinical trial to improve depression care in a real-world diverse MS cohort from an academic MS centre in Northern California: MS CATCH study protocol

Autor: Christina Mangurian, Anthony Feinstein, Ann Lazar, Riley Bove, Kyra Henderson, Jennifer Reihm, Kanishka Koshal, Jaeleene Wijangco, Nicolette Miller, Narender Sara, Marianne Doyle, Alicia Mallory, Judith Sheridan, Chu-Yueh Guo, Lauren Oommen

Publikováno v: BMJ Open, Vol 14, Iss 2 (2024)

Introduction Depression occurs in over 50% of individuals living with multiple sclerosis (MS) and can be treated using many modalities. Yet, it remains: under-reported by patients, under-ascertained by clinicians and under-treated. To enhance these t

Externí odkaz: https://doaj.org/article/57a0db14fb0440b588f1db28669ca814

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Emergency department visits and emergency-to-inpatient admissions for abnormal uterine bleeding in the USA nationwide

Autor: Jessica Grubman, Mitzi Hawkins, Sara Whetstone, Meg Autry, Ann Lazar, George F Sawaya, Vanessa Jacoby

Publikováno v: Emergency Medicine Journal. 40:326-332

BackgroundAbnormal uterine bleeding (AUB) is a common but understudied gynaecological problem, and data are lacking on emergency department (ED) visits and associated ED-to-inpatient admissions for AUB. This project aims to further understanding of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042f320a6bc9b447bb8c480aa9c7532c
https://doi.org/10.1136/emermed-2021-211878

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A Measurement-Based Protocol Improves Interrater Agreement and Accuracy of Right Ventricular Systolic Pressure Assessment by Echocardiography in Children: A Call for Quality Improvement

Autor: Hythem Nawaytou, Christine Springston, Ann Lazar, Samuel Keller, Whitnee Hogan, Nicole Cresalia, Shabnam Peyvandi, Mark Cocalis, Anita Moon-Grady, Michael Brook

Publikováno v: Journal of the American Society of Echocardiography. 35:1091-1100

Echocardiographic measurements carry the promise of improving interrater (IR) agreement over subjective assessment. The aim of this study was to assess the effect of implementing a measurement-based protocol on IR agreement and accuracy in reporting

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d937a8ad609c75aaf7af2513478a37
https://doi.org/10.1016/j.echo.2022.06.014

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Data from Validation of Anticorrelated TGFβ Signaling and Alternative End-Joining DNA Repair Signatures that Predict Response to Genotoxic Cancer Therapy

Autor: Mary Helen Barcellos-Hoff, Alan Ashworth, Sue S. Yom, Jocelyn Chapman, Ann Lazar, Jian-Hua Mao, Ferran Guedea, Isabel Linares, Josep Piulats, Patrick Ha, Miquel Angel Pujana, Qi Liu, Ines Guix

Purpose:Loss of TGFβ signaling increases error-prone alternative end-joining (alt-EJ) DNA repair. We previously translated this mechanistic relationship as TGFβ and alt-EJ gene expression signatures, which we showed are anticorrelated across cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cab3f688f92099e0a0d2004ac6e0145
https://doi.org/10.1158/1078-0432.c.6531285

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Validation of anti-correlated TGFβ signaling and alternative end-joining DNA repair signatures that predict response to genotoxic cancer therapy

Autor: Ines Guix, Qi Liu, Miquel Angel Pujana, Patrick Ha, Josep Piulats, Isabel Linares, Ferran Guedea, Jian-Hua Mao, Ann Lazar, Jocelyn Chapman, Sue S. Yom, Alan Ashworth, Mary Helen Barcellos-Hoff

Publikováno v: Clin Cancer Res
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 28, iss 7

Purpose: Loss of TGFβ signaling increases error-prone alternative end-joining (alt-EJ) DNA repair. We previously translated this mechanistic relationship as TGFβ and alt-EJ gene expression signatures, which we showed are anticorrelated across cance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daf242d2e9cb17caf6cb6b94934b885e
https://europepmc.org/articles/PMC8976728/

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