Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Ann L Miller"'
Autor:
Torey R Arnold, Joseph H Shawky, Rachel E Stephenson, Kayla M Dinshaw, Tomohito Higashi, Farah Huq, Lance A Davidson, Ann L Miller
Publikováno v:
eLife, Vol 8 (2019)
Cellular forces sculpt organisms during development, while misregulation of cellular mechanics can promote disease. Here, we investigate how the actomyosin scaffold protein anillin contributes to epithelial mechanics in Xenopus laevis embryos. Increa
Externí odkaz:
https://doaj.org/article/b2e8d36113274923811bc67c9beb8534
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101622- (2022)
Summary: Traditional fluorescent proteins exhibit limitations in brightness and photostability that hinder optimal characterization of the dynamic cellular behavior of proteins of interest. SNAP- and Halo-tagging are alternatives to traditional fluor
Externí odkaz:
https://doaj.org/article/e85b0080e84b4bbbbd861d0bde54e804
Autor:
Emily L. Fishman, Kyoung Jo, Quynh P. H. Nguyen, Dong Kong, Rachel Royfman, Anthony R. Cekic, Sushil Khanal, Ann L. Miller, Calvin Simerly, Gerald Schatten, Jadranka Loncarek, Vito Mennella, Tomer Avidor-Reiss
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
The two zygote centrioles are paternally inherited; however, their development is incompletely understood. Here, the authors show that the distal centriole is remodeled into an atypical centriole which functions as the zygote’s second centriole.
Externí odkaz:
https://doaj.org/article/822008b01b9e47a08f35a9332f552e92
Publikováno v:
Molecular Biology of the Cell. 33
In vertebrates, epithelial cell-cell junctions must rapidly remodel to maintain barrier function as cells undergo dynamic shape-change events. Consequently, localized leaks sometimes arise within the tight junction (TJ) barrier, which are repaired by
Autor:
Jennifer Landino, Marcin Leda, Ani Michaud, Zachary T. Swider, Mariah Prom, Christine M. Field, William M. Bement, Anthony Vecchiarelli, Andrew B. Goryachev, Ann L. Miller
Publikováno v:
Biophysical Journal. 122:167a-168a
Autor:
Tomohito Higashi, Rachel E. Stephenson, Cornelia Schwayer, Karla Huljev, Carl-Philipp Heisenberg, Hideki Chiba, Ann L. Miller
Epithelial barrier function is commonly analyzed using transepithelial electrical resistance (TER), which measures the ion flux across epithelia, or by adding traceable macromolecules to one side of the epithelium and monitoring their passage to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b9e220f11b88b9f9097ef228a2b4f41
https://doi.org/10.1101/2022.09.27.509705
https://doi.org/10.1101/2022.09.27.509705
Autor:
Toni-Ann L. Miller, Eric J. Hyslop
Publikováno v:
Caribbean Journal of Science. 52
Autor:
Zachary T. Swider, Ann L. Miller, George von Dassow, Ani Michaud, Andrew B. Goryachev, William M. Bement, Marcin Leda, Jennifer Landino
Publikováno v:
Curr Biol
Michaud, A, Swider, Z T, Landino, J, Leda, M, Miller, A L, von Dassow, G, Goryachev, A B & Bement, W M 2021, ' Cortical excitability and cell division ', Current Biology, vol. 31, no. 10, pp. PR553-R559 . https://doi.org/10.1016/j.cub.2021.02.053
Michaud, A, Swider, Z T, Landino, J, Leda, M, Miller, A L, von Dassow, G, Goryachev, A B & Bement, W M 2021, ' Cortical excitability and cell division ', Current Biology, vol. 31, no. 10, pp. PR553-R559 . https://doi.org/10.1016/j.cub.2021.02.053
As the interface between the cell and its environment, the cell cortex must be able to respond to a variety of external stimuli. This is made possible in part by cortical excitability, a behavior driven by coupled positive and negative feedback loops
Autor:
Saranyaraajan Varadarajan, Shahana A. Chumki, Rachel E. Stephenson, Eileen R. Misterovich, Jessica L. Wu, Claire E. Dudley, Ivan S. Erofeev, Andrew B. Goryachev, Ann L. Miller
Publikováno v:
Varadarajan, S, Chumki, S A, Stephenson, R, Misterovich, E R, Wu, J L, Dudley, C E, Erofeev, I, Goryachev, A B & Miller, A L 2022, ' Mechanosensitive calcium flashes promote sustained RhoA activation during tight junction remodeling ', Journal of Cell Biology, vol. 221, no. 4, e202105107 . https://doi.org/10.1083/jcb.202105107
Epithelial cell–cell junctions remodel in response to mechanical stimuli to maintain barrier function. Previously, we found that local leaks in tight junctions (TJs) are rapidly repaired by local, transient RhoA activation, termed “Rho flares,”
Autor:
Lotte van den Goor, Ann L. Miller
Publikováno v:
The Journal of cell biology. 221(4)
Tricellular junctions play a critical role in regulating epithelial barrier function. In this issue, Cho et al. (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202009037) demonstrate a novel interaction between tricellulin and α-catenin, which conn