Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ann Kathrine Hansen"'
Autor:
Ann Kathrine Hansen, Lars Erichsen, Stefanie Sach-Friedl, Hanne Haahr, Ananda Basu, Rita Basu, Thomas R. Pieber
Publikováno v:
Diabetes, Obesity & Metabolism
AIM To investigate the mechanisms behind the lower postprandial glucose (PPG) concentrations achieved with fast-acting insulin aspart (faster aspart) than with insulin aspart (IAsp). MATERIALS AND METHODS In a randomized, double-blind, crossover tria
Publikováno v:
Journal of Diabetes Investigation
Introduction Fast‐acting insulin aspart (faster aspart) is insulin aspart (IAsp) in a new formulation with two added excipients (niacinamide and L‐arginine) in order to obtain accelerated absorption after subcutaneous dosing. The present study co
Autor:
S Sach-Friedel, Hanne Haahr, E Jaeckel, Rita Basu, Ann Kathrine Hansen, Thomas R. Pieber, Ananda Basu, Kmd Thomsen
Publikováno v:
Diabetologie und Stoffwechsel.
Autor:
Trine B. Levring, Carsten Geisler, Germana Meroni, Lasse Boding, Ann Kathrine Hansen, Niels Ødum, Charlotte M. Bonefeld, Anders Woetmann
Publikováno v:
APMIS. 123:682-687
We have recently shown that the E3 ubiquitin ligase midline 1 (MID1) is upregulated in murine cytotoxic lymphocytes (CTL), where it controls exocytosis of lytic granules and the killing capacity. Accordingly, CTL from MID1 knock-out (MID1(-/-)) mice
Autor:
Ann Kathrine Hansen, Thomas Hartig Braunstein, Anders Woetmann, Lasse Boding, Carsten Geisler, Morten M. Nielsen, Niels Ødum, Germana Meroni, Charlotte M. Bonefeld
Publikováno v:
Immunity, Inflammation and Disease. 2:262-271
Midline 1 (MID1) is a microtubule-associated ubiquitin ligase that regulates protein phosphatase 2 A levels. Loss-of-function mutations in MID1 lead to the human X-linked Opitz G/BBB (OS) syndrome characterized by defective midline development during
Autor:
Lasse Boding, Charlotte M. Bonefeld, Anders Woetmann, Bo Johansen, Thomas Hartig Braunstein, Niels Ødum, Marina Rode von Essen, Benjamin A. H. Jensen, Carsten Geisler, Allan Randrup Thomsen, Ann Kathrine Hansen, Germana Meroni, Martin Kongsbak
Publikováno v:
European Journal of Immunology. 44:3109-3118
Midline 1 (MID1) is a microtubule-associated ubiquitin ligase that regulates protein phosphatase 2A activity. Loss-of-function mutations in MID1 lead to the X-linked Opitz G/BBB syndrome characterized by defective midline development during embryogen
Autor:
Jens Peter H. Lauritsen, Trine B. Levring, Lasse Boding, Carsten Geisler, Martin Kongsbak, Ann Kathrine Hansen, Niels Ødum, Gottfried Baier, Marina Rode von Essen, Charlotte M. Bonefeld, Anders Woetmann
Publikováno v:
European Journal of Immunology. 43:1659-1666
PKC-θ plays a central role in TCR-induced IL-2 production and T-cell proliferation. The aim of the present study was to analyse how PKC-θ is regulated in human T cells during T-cell activation and differentiation. We show that PKC-θ is found in a
Autor:
Arno Müllbacher, Niels Ødum, Charlotte M. Bonefeld, Carsten Geisler, Martin Kongsbak, Lasse Boding, Ann Kathrine Hansen, Matthias Regner, Marina Rode von Essen
Publikováno v:
European Journal of Immunology. 41:1948-1957
Cytotoxic T (Tc) cells play a key role in the defense against virus infections. Tc cells recognize infected cells via the T-cell receptor (TCR) and subsequently kill the target cells by one or more cytotoxic mechanisms. Induction of the cytotoxic mec
Autor:
Ada M. Kruisbeek, Lasse Boding, Charlotte M. Bonefeld, Bodil Nielsen, Marina Rode von Essen, Allan Randrup Thomsen, Mariëlle C. Haks, Jeppe Madura Larsen, Paul Krimpenfort, Niels Ødum, Carsten Geisler, Jan Pravsgaard Christensen, Ann Kathrine Hansen
Publikováno v:
UC Viden
University of Copenhagen
University of Copenhagen
The CD3γ di-leucine-based motif plays a central role in TCR down-regulation. However, little is understood about the role of the CD3γ di-leucine-based motif in physiological T cell responses. In this study, we show that the expansion in numbers of
Autor:
Jeppe Madura Larsen, Martin Weiss Nielsen, Marina Rode von Essen, Ann Kathrine Hansen, Charlotte M. Bonefeld, Carsten Geisler, Lone Skov, Lasse Boding
Publikováno v:
Contact Dermatitis. 57:300-308
Background: The different role of various immunological effector cells in contact hypersensitivity (CHS) is receiving increased attention. During the past decade, the involvement of different cell types in CHS has been investigated by the use of anti