Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ann Kathrin Wenke"'
Autor:
Ann-Kathrin Wenke, Christian Kjellman, Evy Lundgren-Akerlund, Christian Uhlmann, Nikolas K. Haass, Meenhard Herlyn, Anja K. Bosserhoff
Publikováno v:
Cellular Oncology, Vol 29, Iss 5, Pp 373-386 (2007)
Recently, integrin alpha10 was described as a collagen type II-binding integrin expressed mainly in chondrocytes. However, by array studies we detected integrin alpha10 also to be upregulated in malignant melanoma compared to primary melanocytes. Sub
Externí odkaz:
https://doaj.org/article/4dd4fc2d4b884dfabbe3c27d5f8a3f62
Autor:
Nicolas T. Schwarz, Witigo von Schönfels, Katharina Balschun, Ann Kathrin Wenke, Jochen Haag, Christoph Röcken
Publikováno v:
The Journal of Molecular Diagnostics. 13:436-445
Targeted therapy of advanced colorectal carcinoma (CRC) necessitates KRAS genotyping. Because we were interested in diagnostic and therapeutic consequences, we studied the KRAS, NRAS, PIK3CA exon 20, and BRAF genotypes in synchronous and metachronous
Autor:
Anja K. Bosserhoff, Ann-Kathrin Wenke
Publikováno v:
FEBS Journal. 277:894-902
During embryogenesis, most of the mammalian skeletal system is preformed as cartilaginous structures that ossify later. The different stages of cartilage and skeletal development are well described, and several molecular factors are known to influenc
Publikováno v:
Journal of Molecular Biology. 369:474-488
We report here the crystal structure of a protein from Pyrococcus furiosus (Phr) that represents the first characterized heat shock transcription factor in archaea. Phr specifically represses the expression of heat shock genes at physiological temper
Autor:
Christian Uhlmann, Anja K. Bosserhoff, Christian Kjellman, Evy Lundgren-Akerlund, Meenhard Herlyn, Ann-Kathrin Wenke, Nikolas K. Haass
Publikováno v:
Cellular Oncology : the Official Journal of the International Society for Cellular Oncology
Cellular Oncology, Vol 29, Iss 5, Pp 373-386 (2007)
Cellular Oncology, Vol 29, Iss 5, Pp 373-386 (2007)
Recently, integrin alpha10 was described as a collagen type II-binding integrin expressed mainly in chondrocytes. However, by array studies we detected integrin alpha10 also to be upregulated in malignant melanoma compared to primary melanocytes. Sub
Publikováno v:
Expert review of molecular diagnostics. 11(8)
The analysis of KRAS mutations has become a prerequisite for anti-epidermal growth factor receptor therapy in patients with metastatic colorectal cancers. KRAS mutations are associated with resistance to treatment by monoclonal antibodies such as cet
Publikováno v:
Rheumatology (Oxford, England). 48(11)
Objective The concept of the chondrocyte as a stationary cell surrounded by an apparently impenetrable matrix has been challenged by in vitro observations in recent years. Chondrocyte migration may have a role in remodelling of the cartilage and path
Publikováno v:
The FEBS journal. 276(9)
Activating enhancer-binding protein (AP)-2epsilon was previously described as a new regulator of integrin alpha(10) expression in cartilage. In this study, we analyzed the expression of AP-2epsilon in differentiated chondrocytes and in human mesenchy
Autor:
Vincenzo Russo, Ann Kathrin Wenke, Giovanni Lavorgna, Ugo Orfanelli, Claudio Doglioni, Anja-Katrin Bosserhoff
Publikováno v:
Cell research. 18(11)
It has been proposed that in cancer, where the bulk of the genome becomes hypomethylated, there is an increase in transcriptional noise that might lead to the generation of antisense transcripts that could affect the function of key oncosuppressor ge
Publikováno v:
Biochemical and biophysical research communications. 345(1)
Expression of integrin alpha10 is initiated at the beginning of chondrogenesis and continues throughout cartilage development in adult cartilage. In our study, we aim to identify regulatory sequences that control the cell-type specific expression of