Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ann Kari, Grindheim"'
Autor:
Sudarshan S. Patil, Vipul Panchal, Trude Røstbø, Sofya Romanyuk, Hanne Hollås, Ruth Brenk, Ann Kari Grindheim, Anni Vedeler
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Introduction: The regulation of intracellular functions in mammalian cells involves close coordination of cellular processes. During recent years it has become evident that the sorting, trafficking and distribution of transport vesicles and mRNA gran
Externí odkaz:
https://doaj.org/article/fe94637ba7a64aaba615f5c71146eff2
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Introduction: Annexin A2 (AnxA2) plays a critical role in cell transformation, immune response, and resistance to cancer therapy. Besides functioning as a calcium- and lipidbinding protein, AnxA2 also acts as an mRNA-binding protein, for instance, by
Externí odkaz:
https://doaj.org/article/3362a26f2401430d93c5c6cc26c9ad4a
Autor:
Oscar Aubi, Karina S. Prestegård, Kunwar Jung-KC, Tie-Jun Sten Shi, Ming Ying, Ann Kari Grindheim, Tanja Scherer, Arve Ulvik, Adrian McCann, Endy Spriet, Beat Thöny, Aurora Martinez
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Phenylketonuria (PKU) is caused by autosomal recessive variants in phenylalanine hydroxylase (PAH) and can lead to neurotoxicity. Here the authors describe a mouse model of PKU based on a mutation in phenylalanine hydroxylase (R261Q) which replicates
Externí odkaz:
https://doaj.org/article/020954ecba5d415e91bb8d1edb0ad49b
Autor:
Ann Kari Grindheim, Anni Vedeler
Publikováno v:
Communicative & Integrative Biology, Vol 9, Iss 4 (2016)
Annexin A2 (AnxA2) is present in multiple cellular compartments and interacts with numerous ligands including calcium, proteins, cholesterol, negatively charged phospholipids and RNA. These interactions are tightly regulated by its post-translational
Externí odkaz:
https://doaj.org/article/b727913e26994293a1fe602e08543b87
Autor:
Jan Haavik, Peter Ruoff, Gyrid Nygaard, Peter D. Szigetvari, Marte I. Flydal, Aurora Martinez, Rune Kleppe, Ann Kari Grindheim
Publikováno v:
Journal of Personalized Medicine
Journal of Personalized Medicine, Vol 11, Iss 1186, p 1186 (2021)
Journal of Personalized Medicine, Vol 11, Iss 1186, p 1186 (2021)
Dopa-responsive dystonia (DRD) is a rare movement disorder associated with defective dopamine synthesis. This impairment may be due to the fact of a deficiency in GTP cyclohydrolase I (GTPCHI, GCH1 gene), sepiapterin reductase (SR), tyrosine hydroxyl
Autor:
Elin, Strand, Hanne, Hollås, Siri Aastedatter, Sakya, Sofya, Romanyuk, Mikko E V, Saraste, Ann Kari, Grindheim, Sudarshan S, Patil, Anni, Vedeler
Publikováno v:
RNA Biology
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The expression and localization of the oncoprotein c-Myc is highly regulated at the level of transcription, mRNA transport, translation, as well as stability of the protein. We previously showed that Annexin A2 (AnxA2) binds to a specific localizatio
Autor:
Hanne Hollås, Elin Aareskjold, Ann Kari Grindheim, Johan R. Lillehaug, Marianne Goris, Anni Vedeler
Publikováno v:
Biochemical Pharmacology
Besides altering its own expression during cell transformation, Annexin A2 is upregulated during the progression of many cancer types and also plays key roles during viral infection and multiplication. Consequently, there has been great interest in A
Autor:
Ming Ying, Ann Kari Grindheim, Kunwar Jung-KC, Tie-Jun Sten Shi, Beat Thöny, Arve Ulvik, Endy Spriet, Tanja Scherer, Aurora Martinez, Oscar Aubi, Adrian McCann, Karina S. Prestegård
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Phenylketonuria (PKU) is caused by autosomal recessive variants in phenylalanine hydroxylase (PAH), leading to systemic accumulation of L-phenylalanine (L-Phe) that may reach neurotoxic levels. A homozygous Pah-R261Q mouse, with a highly prevalent mi
Autor:
Ann Kari Grindheim, Hanne Hollås, Sofya Romanyuk, Siri Aastedatter Sakya, Sudarshan Patil, Anni Vedeler, Elin Strand, Mikko Erik Vedeler Saraste
Publikováno v:
RNA Biology
The expression and localization of the oncoprotein c-Myc is highly regulated at the level of transcription, mRNA transport, translation, as well as stability of the protein. We previously showed that Annexin A2 (AnxA2) binds to a specific localizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21733eaa4ad4fd708d66198234e7b42c
https://hdl.handle.net/11250/2786702
https://hdl.handle.net/11250/2786702
Autor:
Aase M. Raddum, Lasse Evensen, Hanne Hollås, Ann Kari Grindheim, James B. Lorens, Anni Vedeler
Publikováno v:
PLoS ONE, Vol 8, Iss 10 (2013)
Externí odkaz:
https://doaj.org/article/31f9add0dfe949bcbb1f3f9e4ede2bbc