Výsledky vyhledávání - "Ann J. L. Crowther"

4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease

Autor: Willem I. de Boer, Jan Stolk, Irfan Rahman, Pieter S. Hiemstra, Annemarie van Schadewijk, Ann J. L. Crowther, William MacNee

Publikováno v: American Journal of Respiratory and Critical Care Medicine, 166, 490-495. American Thoracic Society

Cigarette smoking results in oxidative stress and inflammation in the lungs, which are involved in the pathogenesis of chronic obstructive pulmonary disease (COPD). 4-Hydroxy-2-nonenal (4-HNE), a highly reactive diffusible product of lipid peroxidati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b84f4c40d9fa6a6d56fbaa586d939a9e
https://pure.eur.nl/en/publications/acb6b518-a3ee-4093-9d5c-cc32adf93374

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The effect of smoking on the transcriptional regulation of lung inflammation in patients with chronic obstructive pulmonary disease

Autor: William MacNee, Luis A Jimenez, Ken Donaldson, Ellen M Drost, Ruth J. Mayer, Ann J. L. Crowther, Thomas B. Leonard, Patryk Szulakowski

Publikováno v: American journal of respiratory and critical care medicine. 174(1)

Chronic obstructive pulmonary disease (COPD) is believed to result from an abnormal inflammatory response in the lungs to noxious particles and gases usually found in cigarette smoke.In this study, the molecular mechanisms for the enhanced proinflamm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cbbd701ff99393a2fcaee7ef95b8209
https://pubmed.ncbi.nlm.nih.gov/16793997

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