Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ann Hozeska"'
Autor:
Hua Teng, Michael Chopp, Ann Hozeska-Solgot, Lihong Shen, Mei Lu, Clark Tang, Zheng Gang Zhang
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33444 (2012)
The molecular mechanisms underlying cerebral angiogenesis have not been fully investigated. Using primary mouse brain endothelial cells (MBECs) and a capillary-like tube formation assay, we investigated whether the sonic hedgehog (Shh) signaling path
Externí odkaz:
https://doaj.org/article/31fcae58cb7246b789902da29ed2da8d
Autor:
Xian Shuang Liu, Michael Chopp, Rui Lan Zhang, Tang Tao, Xin Li Wang, Haifa Kassis, Ann Hozeska-Solgot, Li Zhang, Charles Chen, Zheng Gang Zhang
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23461 (2011)
The Notch signaling pathway regulates adult neurogenesis under physiological and pathophysiological conditions. MicroRNAs are small non-coding RNA molecules that regulate gene expression. The present study investigated the effect of miR-124a on the N
Externí odkaz:
https://doaj.org/article/5718a7552ef34490abe6472890dbb599
Autor:
Michael Chopp, Yi Sheng Cui, Rui Lan Zhang, Long Fei Jia, Zheng Gang Zhang, Haifa Kassis, Xian Shuang Liu, Ann Hozeska-Solgot, Charles Chen
Publikováno v:
Neuroscience. 220:313-321
Acute treatment of stroke with histone deacetylase (HDAC) inhibitors has been shown to reduce ischemic cell damage; however, it is unclear whether delayed treatment with HDAC inhibitors will contribute to the brain repair and plasticity. In the prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6877fb5974fe320455add2f44a842087
https://doi.org/10.1016/j.neuroscience.2012.06.012
https://doi.org/10.1016/j.neuroscience.2012.06.012
Autor:
Hongqi Xin, Xianshuang Liu, Ann Hozeska-Solgot, Yi Li, Li Hong Shen, Zheng Gang Zhang, Michael Chopp, Rui Lan Zhang
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 31:2181-2188
Multipotent mesenchymal stromal cells (MSCs) increase tissue plasminogen activator (tPA) activity in astrocytes of the ischemic boundary zone, leading to increased neurite outgrowth in the brain. To probe the mechanisms that underlie MSC-mediated act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baa2b008c7dbe9e2d00807f6caf69a98
https://doi.org/10.1038/jcbfm.2011.116
https://doi.org/10.1038/jcbfm.2011.116
Autor:
Michael Chopp, Xinli Wang, Ann Hozeska-Solgot, Ben Buller, Rui Lan Zhang, Xianshuang Liu, Li Zhang, Zheng Gang Zhang
Publikováno v:
FEBS Journal. 277:4299-4307
MicroRNAs are small RNAs that attenuate protein expression by complementary binding to the 3'-UTR of a target mRNA. Currently, very little is known about microRNAs after cerebral ischemia. In particular, microRNA-21 (miR-21) is a strong antiapoptotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b43d14b512a63f875bb3539974c02b42
https://doi.org/10.1111/j.1742-4658.2010.07818.x
https://doi.org/10.1111/j.1742-4658.2010.07818.x
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 27:2470-2475
Objective— We tested the hypothesis that the phosphatidylinositol-3 kinase (PI3K)/Akt pathway mediates the neuroprotective effect of combination therapy of atorvastatin and tissue-type plasminogen activator (tPA) in rats after stroke. Methods and R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81d1ec3ba299c2a013c15a383d9834a8
https://doi.org/10.1161/atvbaha.107.150748
https://doi.org/10.1161/atvbaha.107.150748
Autor:
Faith M. Strickland, Ann Hozeska, Rui Lan Zhang, Cynthia Roberts, Zheng Gang Zhang, Ying Wang, Lei Wang, Thomas J. Hornyak, Michael Chopp, Zhongxian Jiao
Publikováno v:
Developmental Biology. 296:396-408
DOPAchrome tautomerase (Dct) functions downstream of tyrosinase in the biosynthetic pathway of eumelanin by catalyzing the conversion of dopachrome to 5,5-dihydroxyindole-2-carboxylic acid (DHICA) in pigment cells. Dct transcription is regulated dire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d1c79d83093b368e2a248a074e62ff6
https://doi.org/10.1016/j.ydbio.2006.06.006
https://doi.org/10.1016/j.ydbio.2006.06.006
Autor:
Michael Chopp, Rui Lan Zhang, Yvonne LeTourneau, Sara R Gregg, Ann Hozeska-Solgot, Lei Wang, Ying Wang, Zheng Gang Zhang
Publikováno v:
The Journal of Neuroscience. 26:5996-6003
We investigated the hypothesis that endothelial cells activated by erythropoietin (EPO) promote the migration of neuroblasts. This hypothesis is based on observationsin vivothat treatment of focal cerebral ischemia with EPO enhances the migration of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::604302aa5cf9b1ac634e6fc3f3073955
https://doi.org/10.1523/jneurosci.5380-05.2006
https://doi.org/10.1523/jneurosci.5380-05.2006
Autor:
Michael Chopp, Li Zhang, Nancy E. Stagliano, Xianshuang Liu, Mei Lu, Zheng Gang Zhang, William Riordan, Ann Hozeska
Publikováno v:
Thrombosis and Haemostasis. 95:166-173
SummaryStroke elicits a progressive vascular dysfunction, which contributes to the evolution of brain injury. Thrombolysis with tissue plasminogen activator (tPA) promotes adverse vascular events that limit the therapeutic window of stroke to three h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35060e568d96ceaba20122246d0837b3
https://doi.org/10.1160/th05-07-0477
https://doi.org/10.1160/th05-07-0477
Autor:
Rui Lan Zhang, Lian Li, Michael Chopp, Daniel C. Morris, Quan Jiang, Xianshuang Liu, Li Zhang, Mei Lu, He Meng, Guang Liang Ding, Chunling Zhang, Zheng Gang Zhang, Ann Hozeska
Publikováno v:
Circulation. 112:3486-3494
Background— Microvascular dysfunction posttreatment of stroke with recombinant human tissue-type plasminogen activator (rht-PA) constrains the therapeutic window to 3 hours. Statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) promo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd622524e6779ccf4c439a50edd8865
https://doi.org/10.1161/circulationaha.104.516757
https://doi.org/10.1161/circulationaha.104.516757