Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ann F, Ramsdell"'
Autor:
Adam Hartstone-Rose, Ann F. Ramsdell, Shrusti S. Patel, Anna Dvorkin-Gheva, John A. Hassell, Daping Fan, Huda I Atiya, Rachel L Parker, Johnie Hodge
Publikováno v:
Anticancer Res
Background Low success rates in oncology drug development are prompting re-evaluation of preclinical models, including orthotopic tumor engraftment. In breast cancer models, tumor cells are typically injected into mouse mammary fat pads (MFP). Howeve
Publikováno v:
Oncogene
Significant left-right (L-R) differences in tumor incidence and disease outcome occur for cancers of paired organs, including the breasts; however, the basis for this laterality is unknown. Here, we show that despite their morphological symmetry, lef
Left–right asymmetry is a phenomenon that has a broad appeal—to anatomists, developmental biologists and evolutionary biologists—because it is a morphological feature of organisms that spans scales of size and levels of organization, from unice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87502b3a8097f8af2254fd8fb7393c0c
https://europepmc.org/articles/PMC5104499/
https://europepmc.org/articles/PMC5104499/
Autor:
Carol A. Eisenberg, Jayne M. Bernanke, Lisa Martin, Leonard M. Eisenberg, Ann F. Ramsdell, Mathieu C. Rémond, Nadejda V. Mezentseva, Momka Bratoeva
Publikováno v:
Development, Growth & Differentiation. 54:153-166
Lithium is a commonly used drug for the treatment of bipolar disorder. At high doses, lithium becomes teratogenic, which is a property that has allowed this agent to serve as a useful tool for dissecting molecular pathways that regulate embryogenesis
Autor:
Leonard M. Eisenberg, Lisa Martin, Ann F. Ramsdell, Momka Bratoeva, Nadejda V. Mezentseva, Carol A. Eisenberg
Publikováno v:
Stem Cells and Development. 20:1973-1983
WNT signaling has been shown to influence the development of the heart. Although recent data suggested that canonical WNTs promote the emergence and expansion of cardiac progenitors in the pregastrula embryo, it has long been accepted that once gastr
Autor:
Ann F. Ramsdell
Publikováno v:
Developmental Biology. 288(1):1-20
Cellular and molecular left–right differences that are present in the mesodermal heart fields suggest that the heart is lateralized from its inception. Left–right asymmetry persists as the heart fields coalesce to form the primary heart tube, and
Publikováno v:
Anticancer research. 34(3)
Fractal dimension has emerged as a clinically useful tool in the diagnosis and management of breast cancer. The aim of the present study was to determine if fractal dimension can be applied for the analysis of a pre-clinical breast cancer mouse model
Autor:
Ann F. Ramsdell, H. Joseph Yost
Publikováno v:
Trends in Genetics. 14:459-465
Patterning of all tissues and organs in the vertebrate embryo occurs along the dorsoventral (DV), anteroposterior (AP), and left–right (LR) body axes. Whereas significant progress has been made in identifying the processes underlying DV and AP patt
Autor:
Roger R. Markwald, Ann F. Ramsdell
Publikováno v:
Developmental Biology. 188(1):64-74
Valvuloseptal morphogenesis of the primitive heart tube into a four-chambered organ requires the formation of endocardial cushion tissue. The latter is the outcome of an inductive interaction in which endocardial (endothelial) cells are induced to tr
Publikováno v:
Development (Cambridge, England). 133(7)
The significant morbidity and mortality associated with laterality disease almost always are attributed to complex congenital heart defects (CHDs),reflecting the extreme susceptibility of the developing heart to disturbances in the left-right (LR) bo