Výsledky vyhledávání - "Ann E. Stitzel"

On the origin of C3 nephritic factor (antibody to the alternative pathway C3 convertase): Evidence for the Adam and Eve concept of autoantibody production

Autor: Ann E. Stitzel, George C. Tsokos, Roger E. Spitzer

Publikováno v: Clinical Immunology and Immunopathology. 64:177-183

The antibody to the alternative pathway C3 convertase, designated C3 nephritic factor or C3NeF, is an autoantibody that is produced in everyone from the time of birth. The elaboration of C3NeF utilizes germline V-region genes which undergo antigen-dr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bd0486393476abcf6819605a011f9f1
https://doi.org/10.1016/0090-1229(92)90197-v

Zobrazit plný text záznamu

Study of the idiotypic response to autoantibody to the alternative pathway convertase in normal individuals, patients with membranoproliferative glomerulonephritis, and experimental animals

Autor: George C. Tsokos, Ann E. Stitzel, Roger E. Spitzer

Publikováno v: Clinical Immunology and Immunopathology. 62:291-294

We studied the fluctuation of autoantibody to the alternative pathway C3C5 convertase (C3NeF) and its autoantiidiotypic antibodies, Ab2α and Ab2β, in normal individuals, patients with membranoproliferative glomerulonephritis (MPGN), and New Zealand

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::594b235c9949c905ea9ee3e5f78a8307
https://doi.org/10.1016/0090-1229(92)90105-w

Zobrazit plný text záznamu

Loss of Autoantibody Activity by Alteration in Autoantigen

Autor: Ann E. Stitzel, Roger E. Spitzer

Publikováno v: Clinical Immunology and Immunopathology. 80:211-213

C3 nephritic factor (C3NeF) is an autoantibody produced by patients with membranoproliferative glomerulonephritis (MPGN); it is thought to be responsible for the continued breakdown of C3 in these patients. We have studied three patients with MPGN fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a412d778c82083b161a2ca6c8458ad7
https://doi.org/10.1006/clin.1996.0116

Zobrazit plný text záznamu

Nephritic Factor Autoantibodies

Autor: Ann E. Stitzel, Roger E. Spitzer, George C. Tsokos

Publikováno v: Autoantibodies ISBN: 9780444823830

Publisher Summary This chapter provides an overview of pathogenetic role of C3 nephritic factor (C3NeF) autoantibodies alongwith several disease associations. The accumulated data suggest that C3 nephritic factor is a typical antibody. Germline genes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b69832baacc66a49684acca274067423
https://doi.org/10.1016/b978-044482383-0/50083-2

Zobrazit plný text záznamu

Nucleotide sequence of a human autoantibody to the alternative pathway C3/C5 convertase (C3NeF)

Autor: George C. Tsokos, K Victor, Roger E. Spitzer, Virginia Pascual, Ann E. Stitzel, J. Donald Capra

Publikováno v: Hybridoma. 12(3)

The production of autoantibodies to the alternative pathway C3/C5 convertase or C3 Nephritic Factor (C3NeF) is one characteristic of membranoproliferative glomerulonephritis. The complete nucleotide sequences of the heavy and light chain variable reg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8b5607636c22aa35125f4c98a404306
https://pubmed.ncbi.nlm.nih.gov/8395463

Zobrazit plný text záznamu

Production of IgG and IgM autoantibody to the alternative pathway C3 convertase in normal individuals and patients with membranoproliferative glomerulonephritis

Autor: George C. Tsokos, Roger E. Spitzer, Ann E. Stitzel

Publikováno v: Clinical immunology and immunopathology. 57(1)

To understand the origin of autoantibody production, we studied the ontogeny of antibody to the alternative pathway C3 convertase (C3 nephritic factor or C3NeF). Peripheral blood mononuclear cells from newborns, normal adults, and patients with membr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f07041ca4b3ad5a87beb07054137f8f2
https://pubmed.ncbi.nlm.nih.gov/1697516

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání