Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ann E. Field"'
Publikováno v:
Molecular and Cellular Biology. 22:5721-5740
Transcription factors of the interferon regulatory factor (IRF) family have been identified as critical mediators of early inflammatory gene transcription in infected cells. We recently determined that, besides IRF-3 and IRF-7, IRF-5 serves as a dire
Reduced pathology following infection with transgenic Leishmania major expressing murine CD40 ligand
Publikováno v:
Infection and immunity. 75(6)
Leishmanization is the inoculation of liveLeishmaniainto the host to vaccinate against subsequent infections. This approach has been largely discontinued due to safety concerns. We have previously shown that combining CD40 ligand (CD40L) withLeishman
Transgenic Leishmania parasites that encode the murine chemokine monocyte chemoattractant protein 1 (MCP-1) were generated. These parasites transcribed MCP-1 mRNA and secreted MCP-1 protein. Infection of BALB/c, C57BL/6, or MCP-1 knockout (KO) mice w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc5fa8873a1f4fce38b949c944533654
https://europepmc.org/articles/PMC1828528/
https://europepmc.org/articles/PMC1828528/
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 173(2)
We have previously reported that the ligation of FcγRs on activated macrophages affected their production of cytokines and their ability to influence T cell activation. Dendritic cells (DC) are important APCs that also express FcγR. In the present