Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Ann E Tilley"'
Autor:
Guoqing Wang, Rui Wang, Yael Strulovici-Barel, Jacqueline Salit, Michelle R Staudt, Joumana Ahmed, Ann E Tilley, Jenny Yee-Levin, Charleen Hollmann, Ben-Gary Harvey, Robert J Kaner, Jason G Mezey, Sriram Sridhar, Sreekumar G Pillai, Holly Hilton, Gerhard Wolff, Hans Bitter, Sudha Visvanathan, Jay S Fine, Christopher S Stevenson, Ronald G Crystal
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0120824 (2015)
Even after quitting smoking, the risk of the development of chronic obstructive pulmonary disease (COPD) and lung cancer remains significantly higher compared to healthy nonsmokers. Based on the knowledge that COPD and most lung cancers start in the
Externí odkaz:
https://doaj.org/article/1b6f44e9a64d47daab4df117cf0df208
Autor:
Justina Hessel, Jonna Heldrich, Jennifer Fuller, Michelle R Staudt, Sharon Radisch, Charleen Hollmann, Ben-Gary Harvey, Robert J Kaner, Jacqueline Salit, Jenny Yee-Levin, Sriram Sridhar, Sreekumar Pillai, Holly Hilton, Gerhard Wolff, Hans Bitter, Sudha Visvanathan, Jay Fine, Christopher S Stevenson, Ronald G Crystal, Ann E Tilley
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85453 (2014)
Smoking and COPD are associated with decreased mucociliary clearance, and healthy smokers have shorter cilia in the large airway than nonsmokers. We hypothesized that changes in cilia length are consistent throughout the airway, and we further hypoth
Externí odkaz:
https://doaj.org/article/920a4ce070f54f71b8b709ce5d214c3e
Publikováno v:
Current Problems in Cancer: Case Reports, Vol 14, Iss , Pp 100290- (2024)
Epithelioid angiosarcoma involving the lung is a rare entity that can present with nodules or consolidations on CT imaging. We describe the case of a 23-year-old woman who presented with chronic cough and pleuritic chest pain and consolidations on CT
Externí odkaz:
https://doaj.org/article/182b0d90567d44e8bcd64f1ddba2edd1
Autor:
Ben-Gary Harvey, Yael Strulovici-Barel, Thomas L Vincent, Jason G Mezey, Ramya Raviram, Cynthia Gordon, Jacqueline Salit, Ann E Tilley, Augustine Chung, Abraham Sanders, Ronald G Crystal
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e72669 (2013)
The distribution of lung disease induced by inhaled cigarette smoke is complex, depending on many factors. With the knowledge that the small airway epithelium (SAE) is the earliest site of smoking-induced lung disease, and that the SAE gene expressio
Externí odkaz:
https://doaj.org/article/aa04e3b9047f4ec39a2834a45205af10
Autor:
Ann E Tilley, Timothy P O'Connor, Neil R Hackett, Yael Strulovici-Barel, Jacqueline Salit, Nancy Amoroso, Xi Kathy Zhou, Tina Raman, Larsson Omberg, Andrew Clark, Jason Mezey, Ronald G Crystal
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22798 (2011)
The first changes associated with smoking are in the small airway epithelium (SAE). Given that smoking alters SAE gene expression, but only a fraction of smokers develop chronic obstructive pulmonary disease (COPD), we hypothesized that assessment of
Externí odkaz:
https://doaj.org/article/e32ec4eff4084ed1bc09f56571e514e3
Autor:
Philip L Leopold, Michael J O'Mahony, X Julie Lian, Ann E Tilley, Ben-Gary Harvey, Ronald G Crystal
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8157 (2009)
BACKGROUND:Whereas cilia damage and reduced cilia beat frequency have been implicated as causative of reduced mucociliary clearance in smokers, theoretically mucociliary clearance could also be affected by cilia length. Based on models of mucociliary
Externí odkaz:
https://doaj.org/article/9ae3ebb167754a9f99c554001f70d5d9
Autor:
Michelle R. Staudt, Thomas L. Vincent, Francisco Agosto-Perez, Benjamin Van de Graaf, Yael Strulovici-Barel, Jason G. Mezey, Robert J. Kaner, Ann E. Tilley, Benjamin A. Raby, Ronald G. Crystal, Jacqueline Salit
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 193:215-217
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5edc80c3c86f511bfdba5d3ff1b31ea7
https://doi.org/10.1164/rccm.201412-2290le
https://doi.org/10.1164/rccm.201412-2290le
Autor:
Yael Strulovici-Barel, Sreekumar G. Pillai, Ben-Gary Harvey, Michelle R. Staudt, Hans Bitter, Cynthia Gordon, Jay S. Fine, Christopher S. Stevenson, Robert J. Kaner, Ronald G. Crystal, Ann E. Tilley, Sudha Visvanathan, Anja Krause, Jason G. Mezey, Holly Hilton, Gerhard Wolff, Charleen Hollmann
Publikováno v:
Thorax. 71(12)
Introduction Increasing evidence links COPD pathogenesis with pulmonary capillary apoptosis. We previously demonstrated that plasma levels of circulating microparticles released from endothelial cells (EMPs) due to apoptosis are elevated in smokers w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8765b039050d119a486317ab1ecd33fa
https://pubmed.ncbi.nlm.nih.gov/27462120
https://pubmed.ncbi.nlm.nih.gov/27462120
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 44:465-473
Human airway epithelial cells cultured in vitro at the air-liquid interface (ALI) form a pseudostratified epithelium that forms tight junctions and cilia, and produces mucin. These cells are widely used in models of differentiation, injury, and repai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cb67a39a292426faa3773714dd1780d
https://doi.org/10.1165/rcmb.2009-0453oc
https://doi.org/10.1165/rcmb.2009-0453oc
Autor:
Ann E. Tilley, Ronald G. Crystal, Jacqueline Salit, Timothy O'Connor, David T. Dang, Andrew G. Clark, Meredith L. Turetz, Yael Strulovici-Barel, B S Matthew Teater, Jason G. Mezey
Publikováno v:
Clinical and Translational Science. 2:260-272
The initial site of smoking‐induced lung disease is the small airway epithelium, which is difficult and time consuming to sample by fiberoptic bronchoscopy. We developed a rapid, office‐based procedure to obtain trachea epithelium without conscio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbbf29ea9e84a38a02f32b7642359f7a
https://doi.org/10.1111/j.1752-8062.2009.00129.x
https://doi.org/10.1111/j.1752-8062.2009.00129.x