Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Ann E Lin"'
1
Akademický článek
Role of Hypoxia Inducible Factor-1α (HIF-1α) in Innate Defense against Uropathogenic Escherichia coli Infection.
Autor: Ann E Lin, Federico C Beasley, Joshua Olson, Nadia Keller, Robert A Shalwitz, Thomas J Hannan, Scott J Hultgren, Victor Nizet
Publikováno v: PLoS Pathogens, Vol 11, Iss 4, p e1004818 (2015)
Uropathogenic E. coli (UPEC) is the primary cause of urinary tract infections (UTI) affecting approximately 150 million people worldwide. Here, we revealed the importance of transcriptional regulator hypoxia-inducible factor-1 α subunit (HIF-1α) in
Externí odkaz: https://doaj.org/article/db10f08b193f496fb43608ee76bb7be3
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2
Akademický článek
Myeloid cell sirtuin-1 expression does not alter host immune responses to Gram-negative endotoxemia or Gram-positive bacterial infection.
Autor: Laura E Crotty Alexander, Brenda J Marsh, Anjuli M Timmer, Ann E Lin, Kayvan Zainabadi, Agnieszka Czopik, Leonard Guarente, Victor Nizet
Publikováno v: PLoS ONE, Vol 8, Iss 12, p e84481 (2013)
The role of sirtuin-1 (SIRT1) in innate immunity, and in particular the influence of SIRT1 on antimicrobial defense against infection, has yet to be reported but is important to define since SIRT1 inhibitors are being investigated as therapeutic agen
Externí odkaz: https://doaj.org/article/0befb1217f794ca68c249b6b2167070b
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3
Augmentation of Urinary Lactoferrin Enhances Host Innate Immune Clearance of Uropathogenic Escherichia coli
Autor: Kathryn A, Patras, Albert D, Ha, Emma, Rooholfada, Joshua, Olson, Satish P, Ramachandra Rao, Ann E, Lin, Victor, Nizet
Publikováno v: Journal of innate immunity. 11(6)
Urinary tract infection (UTI) is a prominent global health care burden. Although UTI is readily treated with antibiotics in healthy adults, complicated cases in immune-compromised individuals and the emerging antibiotic resistance of several uropatho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::264fd094305c001c6550f3248e219636
https://pubmed.ncbi.nlm.nih.gov/31055580
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4
Human milk oligosaccharides inhibit growth of group B
Autor: Ann E, Lin, Chloe A, Autran, Alexandra, Szyszka, Tamara, Escajadillo, Mia, Huang, Kamil, Godula, Anthony R, Prudden, Geert-Jan, Boons, Amanda L, Lewis, Kelly S, Doran, Victor, Nizet, Lars, Bode
Publikováno v: The Journal of biological chemistry. 292(27)
Streptococcus agalactiae (group B Streptococcus, GBS) is a leading cause of invasive bacterial infections in newborns, typically acquired vertically during childbirth secondary to maternal vaginal colonization. Human milk oligosaccharides (HMOs) have
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d80034ea4b0037c8e121da29df3a58fc
https://pubmed.ncbi.nlm.nih.gov/28416607
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5
Abstract 2342: Experimental modeling of acute- and chronic-GvHD by xenotransplanting human donor PBMCs or cord blood CD34+ cells (HSC) into NSG mice
Autor: Ann E. Lin, Annie X. An, Mingfa Zang, Derron Yu, Eunmi Hwang, Israel Romero, Linda Quirino, Marybeth George, Pirouz Daftarian, Wenqing Yang, Henry Li
Publikováno v: Cancer Research. 79:2342-2342
Graft vs. host diseases (GvHD) accounts for 15-30% of deaths following allogenic hematopoietic stem cell transplantation (allo-HSCT) for treatment of malignant diseases. Acute GvHD (aGvHD) typically involves skin, gastrointestinal and hepatic inflamm
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d2504bd20b9f5bfa59134b2915edb265
https://doi.org/10.1158/1538-7445.am2019-2342
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6
Abstract 4124: Expressions of co-inhibitory / co-stimulatory molecules may impact immune checkpoint therapies
Autor: Wushouer Ouerkaxi, Annie X. An, Ann E. Lin, Marybeth George, Derron Yu, Eunmi Hwang, Amy Yamamura, Mingfa Zang, Pirouz Daftarian, Zhongliang Li, Eden Kleiman, Henry Li
Publikováno v: Cancer Research. 79:4124-4124
Screening patient peripheral blood using our proposed non-invasive method can boost the accuracy in selecting proper candidates for immune checkpoint therapy in the clinical setting, thereby leading to higher success in treatment. The immune system i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::283e8b93eb5b5cd41902f0a440ede90a
https://doi.org/10.1158/1538-7445.am2019-4124
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7
Experimental Modeling of Acute- and Chronic-GvHD By Xenotransplanting Human Donor PBMCs or Cord Blood CD34+ Cells (HSC) into NSG Mice
Autor: Ann E Lin, Sonia Reyes, Xiaoyu An, Wenqing Yang, Derron Yu, Duan Dan, Henry Li
Publikováno v: Blood. 132:5684-5684
Graft vs. host diseases (GvHD) is a life-threatening complication accounting for 15-30% of deaths following allergenic hematopoietic stem cell transplantation (allo-HSCT) for treatment of malignant diseases. There are two types of GvHD: acute (aGvHD)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e19e63f05da0c9270d5d0463e679f69f
https://doi.org/10.1182/blood-2018-99-115462
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9
Akademický článek
A Group A Streptococcus ADP-Ribosyltransferase Toxin Stimulates a Protective Interleukin 1β-Dependent Macrophage Immune Response
Autor: Ann E. Lin, Federico C. Beasley, Nadia Keller, Andrew Hollands, Rodolfo Urbano, Emily R. Troemel, Hal M. Hoffman, Victor Nizet
Publikováno v: mBio, Vol 6, Iss 2 (2015)
ABSTRACT The M1T1 clone of group A Streptococcus (GAS) is associated with severe invasive infections, including necrotizing fasciitis and septicemia. During invasive M1T1 GAS disease, mutations in the covRS regulatory system led to upregulation of an
Externí odkaz: https://doaj.org/article/1ae0b0c745294a0da11db658350bbcde
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