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pro vyhledávání: '"Ann E Donnelly"'
Autor:
Jennifer Brennan, Lalit Jain, Sofia Garman, Ann E Donnelly, Erik Scott Wright, Kevin Jamieson
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 7, p e1010311 (2022)
Antibiotic resistance is an important public health problem. One potential solution is the development of synergistic antibiotic combinations, in which the combination is more effective than the component drugs. However, experimental progress in this
Externí odkaz:
https://doaj.org/article/ea7137edadf649d484822793f5c4a527
Autor:
Ann E. Donnelly, Nithya Narayanan, Caroline M. C. Birer-Williams, Travis J. DeWolfe, Rosalie K. Chu, Christopher R. Anderton, Erik S. Wright
Publikováno v:
Appl Environ Microbiol
The bacterial exometabolome consists of a vast array of specialized metabolites, many of which are only produced in response to specific environmental stimuli. For this reason, it is desirable to control the extracellular environment with a defined g
Autor:
Mark D. Hurwitz, Ann E. Donnelly
Publikováno v:
Chemotherapy and Immunotherapy in Urologic Oncology ISBN: 9783030520205
A high percentage of patients with metastatic prostate cancer have evidence of bone metastases that are either symptomatic or visible on radiographic imaging (Roodman, N Engl J Med 350:1655–1664, 2004). Patients with osteoblastic metastatic disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2905528e420b15f124aa7b83bf63e644
https://doi.org/10.1007/978-3-030-52021-2_10
https://doi.org/10.1007/978-3-030-52021-2_10
Autor:
Ann E. Donnelly, Robert B. Den
Publikováno v:
Chemotherapy and Immunotherapy in Urologic Oncology ISBN: 9783030520205
Radiation therapy works by generating free radicals that result in DNA damage, cell death, and tumor regression. Waves that are produced during therapeutic radiotherapy, most often X-ray or gamma-ray photons, act as sources of energy that disrupt orb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f4a78241c4b980c8475255c99a55263
https://doi.org/10.1007/978-3-030-52021-2_6
https://doi.org/10.1007/978-3-030-52021-2_6
Publikováno v:
Nature Chemical Biology. 14:253-255
Producing novel enzymes that are catalytically active in vitro and biologically functional in vivo is a key goal of synthetic biology. Here we describe Syn-F4, the first de novo protein that meets both criteria. Purified Syn-F4 hydrolyzes the siderop