Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Ann E, Aust"'
Autor:
Kevin R. Smith, Ya Mei Zhou, Kent E. Pinkerton, Ann E. Aust, Chao-Yin Chen, Caiyun Zhong, Ian M. Kennedy
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 73:837-847
Greater risk of adverse effects from particulate matter (PM) has been noted in susceptible subpopulations, such as children. However, the physicochemical components responsible for these biological effects are not understood. As critical constituents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cb1b7e0fab0ce5a796cf14f97d1f637
https://doi.org/10.1080/15287391003689366
https://doi.org/10.1080/15287391003689366
Publikováno v:
Apoptosis. 12:433-447
Exposure of human lung epithelial (A549) cells to asbestos fibers causes apoptosis, which is largely attributed to release of iron and generation of reactive oxygen species (ROS) within the cells. To mimic the highly oxidative environment generated b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::015cedb142bfb571a70194ce1451c540
https://doi.org/10.1007/s10495-006-0577-8
https://doi.org/10.1007/s10495-006-0577-8
Publikováno v:
Toxicological Sciences. 93:390-399
Although primary particle emissions of ash from coal-fired power plants are well controlled, coal fly ash (CFA) can still remain a significant fraction of the overall particle exposure for some plant workers and highly impacted communities. The effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5154fed3387ba2173915df8953c42c57
https://doi.org/10.1093/toxsci/kfl062
https://doi.org/10.1093/toxsci/kfl062
Publikováno v:
Toxicology and Applied Pharmacology. 210:70-77
Crocidolite, containing 27% iron by weight, is the most carcinogenic form of asbestos. Crocidolite fibers are endocytized by alphavbeta5 integrin receptors in rabbit pleural mesothelial cells. We show here that crocidolite fibers are endocytized in h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aa528db0061ccd4f49ff6464d9ed647
https://doi.org/10.1016/j.taap.2005.07.017
https://doi.org/10.1016/j.taap.2005.07.017
Publikováno v:
Aerosol Science and Technology. 39:85-91
A novel design for a dry-aerosol generator that efficiently produces a well-dispersed dust suspension using small quantities of a PM2.5-enriched powder sample is described. The motivation to develop a highly efficient dry-aerosol particle generator w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9aa8e36a02d4e7f2965f739f5a1c7124
https://doi.org/10.1080/027868290903899
https://doi.org/10.1080/027868290903899
Autor:
Autumn A. Hu, Ann E. Aust, Frank E. Huggins, JoAnn S. Lighty, Kevin R. Smith, John M. Veranth
Publikováno v:
Chemical Research in Toxicology. 13:161-164
Iron speciation by Mössbauer spectroscopy indicates that ferric iron in an aluminosilicate glass phase is the source of the bioavailable iron in coal fly ash and that this iron species is associated with combustion particles, but not with crustal du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13d7641b14777a5df4a71ecbcf3a6f0d
https://doi.org/10.1021/tx9902136
https://doi.org/10.1021/tx9902136
Autor:
Sara L. Dansie, Ann E. Aust, Kevin R. Smith, Autumn A. Hu, John M. Veranth, Matthew L. Huggins, James B. Griffin, JoAnn S. Lighty
Publikováno v:
Aerosol Science and Technology. 32:127-141
Laboratory methods to produce particle samples from known, reproducible sources with sufficient mass to perform both detailed characterization and replicated in vitro toxicological assays are described. These samples are being used to study the abili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13e5810db120b42472ecd2166a2e39bc
https://doi.org/10.1080/027868200303830
https://doi.org/10.1080/027868200303830
Publikováno v:
Inhalation Toxicology. 12:75-80
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82ce5f198ff74e3a0cc56f893ea3fcba
https://doi.org/10.1080/08958370050164905
https://doi.org/10.1080/08958370050164905
Publikováno v:
Research on Chemical Intermediates. 25:95-109
In order to investigate the molecular mechanism whereby iron in asbestos and in other iron containing fibres plays a crucial role in fibre induced carcinogenicity, two Fe2+-exchanged zeolites (Y and H-ZSM-5) have been prepared and used as model solid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0cc3644ef0928072689b0be1b542e3b
https://doi.org/10.1163/156856799x00400
https://doi.org/10.1163/156856799x00400
Autor:
Ann E. Aust, Sun-Hee Park
Publikováno v:
Archives of Biochemistry and Biophysics. 360:47-52
Treatment of human lung epithelial (A549) cells with crocidolite asbestos resulted in the induction of the inducible form of nitric oxide synthase (iNOS), production of NO, and a dramatic decrease in intracellular reduced glutathione (GSH). Iron, mob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c2c3bdf417251752cdd39cbc2598f81
https://doi.org/10.1006/abbi.1998.0950
https://doi.org/10.1006/abbi.1998.0950