Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ann C. Palladino"'
Publikováno v:
eLife, Vol 7 (2018)
The Maternal Embryonic Leucine Zipper Kinase (MELK) has been identified as a promising therapeutic target in multiple cancer types. MELK over-expression is associated with aggressive disease, and MELK has been implicated in numerous cancer-related pr
Externí odkaz:
https://doaj.org/article/74b1625563b9473ca17e33fb23458412
Autor:
Zachary C. Galluzzo, Ann Lin, Christopher J. Giuliano, Jason M. Sheltzer, Connor Abramowicz, Luwei Liu, Alexander R. Chait, Erin L. Sausville, Kristen M. John, Ann C. Palladino, Devon A. Lukow, Clara Tucker, Monet Lou Yuan
Publikováno v:
Sci Transl Med
Ninety-seven percent of drug-indication pairs that are tested in clinical trials in oncology never advance to receive U.S. Food and Drug Administration approval. While lack of efficacy and dose-limiting toxicities are the most common causes of trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::601dae8a25111fc2527d4f970c618ff8
https://doi.org/10.1126/scitranslmed.aaw8412
https://doi.org/10.1126/scitranslmed.aaw8412
The Maternal Embryonic Leucine Zipper Kinase (MELK) has been identified as a promising therapeutic target in multiple cancer types. MELK over-expression is associated with aggressive disease, and MELK has been implicated in numerous cancer-related pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33d508cb6fefd2f365920ac92ea9947e
https://doi.org/10.1101/203984
https://doi.org/10.1101/203984
Publikováno v:
Cancer Research. 78:837A-837A
The Maternal Embryonic Leucine Zipper Kinase (MELK) has been identified as a promising therapeutic target in multiple cancer types. MELK over-expression is associated with aggressive disease, and MELK has been implicated in numerous cancer-related pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bad5bde2dc433d230fc6b8a14671bd3
https://doi.org/10.1158/1538-7445.am2018-837a
https://doi.org/10.1158/1538-7445.am2018-837a