Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ann C. Cunningham"'
Autor:
Lynn M. Hames, Ranjeny Thomas, Robin T. Nelson, William H. Brissette, Lisa S. Hayes, Ronald P. Gladue, Paul D. Lira, Ann C. Cunningham, Shaun R. McColl, James G. Boyd, Timothy Joseph Paradis, Kuldeep S. Neote
Publikováno v:
Genomics. 73:28-37
We describe the genomic organization of a recently identified CC chemokine, MIP3 alpha /CCL20 (HGMW-approved symbol SCYA20). The MIP-3 alpha /CCL20 gene was cloned and sequenced, revealing a four exon, three intron structure, and was localized by FIS
Autor:
John Charles Kath, Kimberly A. Verdries, Kevin Koch, Stephan Grissmer, Angela Nguyen, Paul C. Canniff, Ann C. Cunningham, Robert J. Mather, Matthew J. Bruns, Douglas C. Hanson, E. Edward Mena, K. George Chandy, Michael D. Cahalan, Carol B. Donovan, Heiko Rauer, Burgess Laurence E, George A. Gutman, James P. Rizzi
Publikováno v:
British Journal of Pharmacology. 126:1707-1716
UK-78,282, a novel piperidine blocker of the T lymphocyte voltage-gated K+ channel, Kv1.3, was discovered by screening a large compound file using a high-throughput 86Rb efflux assay. This compound blocks Kv1.3 with a IC50 of ∼200 nM and 1 : 1 stoi
Autor:
Thomas G. Turi, Songqing Na, Ann C. Cunningham, Jeffrey Herbert Hanke, Dennis E. Danley, Gary M. Bokoch, Tsung-Hsien Chuang
Publikováno v:
Journal of Biological Chemistry. 271:11209-11213
Apoptosis (programmed cell death) is a fundamental process for normal development of multicellular organisms, and is involved in the regulation of the immune system, normal morphogenesis, and maintenance of homeostasis, ICE/CED-3 family cysteine prot
Autor:
A. M. Laquerre, John D. McNeish, M. Allen, Ann C. Cunningham, Ronald P. Gladue, J. Gardner, Andrey S. Shaw, P. A. Connelly
Publikováno v:
Clinical and experimental immunology. 110(3)
SUMMARY Antigen stimulation of T cells results in a series of biochemical events including the interaction of both SH2 domains of ZAP-70 with phosphorylated ITAMS on the T cell receptor. In order to study the physiological relevance of decreasing nat
Autor:
Lynda J. Kieffer, Jane A. Bennett, John D. McNeish, Paula B. Kavathas, Jeffrey Herbert Hanke, Ann C. Cunningham, Ron P. Gladue
Publikováno v:
International immunology. 8(10)
In our previous work, DNase hypersensitivity mapping was used to identify an enhancer within the human CD8 alpha (hCD8 alpha) gene which allowed T cell-specific expression of a reporter construct in transiently transfected cell lines. To study the ro
Publikováno v:
Experimental cell research. 149(2)
The human S11 surface antigens are expressed on fibroblasts and are coded by a gene on the X-chromosome. We have regionally mapped this gene by examining S11 expression on a panel of hybrid lines which had fragmented the X-chromosome either during ch