It is safe to use transdermal glyceryl trinitrate to lower blood pressure in patients with acute ischaemic stroke with carotid stenosis

Autor: Yongjun Wang, Joanna M Wardlaw, Philip M Bath, Valeria Caso, Jason P Appleton, Lisa J Woodhouse, Andrew Belcher, Daniel Bereczki, Eivind Berge, Hui Meng Chang, Hanne K Christensen, Ronan Collins, John Gommans, Ann C Laska, George Ntaios, Serefnur Ozturk, Gillian M Sare, Szabolcs Szatmari, Nikola Sprigg

Publikováno v: Stroke and Vascular Neurology, Vol 4, Iss 1 (2019)

Background There is concern that blood pressure (BP) lowering in acute stroke may compromise cerebral perfusion and worsen outcome in the presence of carotid stenosis. We assessed the effect of glyceryl trinitrate (GTN) in patients with carotid steno

Externí odkaz: https://doaj.org/article/79a3cc3886ff433d942fbcf28520990d

Effect of continuing versus stopping pre-stroke antihypertensive agents within 12 h on outcome after stroke:A subgroup analysis of the efficacy of nitric oxide in stroke (ENOS) trial

Autor: Lisa J. Woodhouse, Jason P. Appleton, Polly Scutt, Lisa Everton, Gwenllian Wilkinson, Valeria Caso, Anna Czlonkowska, John Gommans, Kailash Krishnan, Ann C. Laska, George Ntaios, Serefnur Ozturk, Stephen Phillips, Stuart Pocock, Kameshwar Prasad, Szabolcs Szatmari, Joanna M. Wardlaw, Nikola Sprigg, Philip M. Bath

Publikováno v: Woodhouse, L J, Appleton, J P, Scutt, P, Everton, L, Wilkinson, G, Caso, V, Czlonkowska, A, Gommans, J, Krishnan, K, Laska, A C, Ntaios, G, Ozturk, S, Phillips, S, Pocock, S, Prasad, K, Szatmari, S, Wardlaw, J M, Sprigg, N & Bath, P M 2022, ' Effect of continuing versus stopping pre-stroke antihypertensive agents within 12 h on outcome after stroke : A subgroup analysis of the efficacy of nitric oxide in stroke (ENOS) trial ', EClinicalMedicine, vol. 44, 101274 . https://doi.org/10.1016/j.eclinm.2022.101274
EClinicalMedicine, Vol 44, Iss, Pp 101274-(2022)
EClinicalMedicine

Background: It is not known whether to continue or temporarily stop existing antihypertensive drugs in patients with acute stroke. Methods: We performed a prospective subgroup analysis of patients enrolled into the Efficacy of Nitric Oxide in Stroke

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e55780fc997f817f7e137575ad1bce87
https://www.pure.ed.ac.uk/ws/files/252725989/PIIS2589537022000049.pdf