Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Ann‐Marie Määttä"'
Autor:
Claudia Ottka, Katariina Vapalahti, Ann‐Marie Määttä, Nanna Huuskonen, Sinikka Sarpanen, Liisa Jalkanen, Hannes Lohi
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 35, Iss 1, Pp 405-414 (2021)
Abstract Background The kidneys have many essential metabolic functions, and metabolic disturbances during decreased renal function have not been studied extensively. Objectives To identify metabolic changes in blood samples with increased serum crea
Externí odkaz:
https://doaj.org/article/44679c0ab1004e9385471d1e32981366
Autor:
Hanna M. Leinonen, Eevi M. Lipponen, Anniina J. Valkama, Heidi Hynynen, Igor Oruetxebarria, Vesa Turkki, Venla Olsson, Jere Kurkipuro, Haritha Samaranayake, Ann-Marie Määttä, Nigel R. Parker, Seppo Ylä-Herttuala, Hanna P. Lesch
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 15, Iss , Pp 63-71 (2019)
The therapeutic efficacy of a lentiviral vector (LV) expressing the herpes simplex virus thymidine kinase (HSV-TK) was studied in an immunocompetent rat glioblastoma model. Intraperitoneal ganciclovir injections (50 mg/kg/day) were administered for 1
Externí odkaz:
https://doaj.org/article/58e30f80fca14c09842389d436188547
Autor:
Anna-Liisa Levonen, Seppo Ylä-Herttuala, Minna U. Kaikkonen, Hanna P. Lesch, Haritha Samaranayake, Jari P. Lappalainen, Jere T. Pikkarainen, Emilia Kansanen, Suvi M. Kuosmanen, Heidi M. Laitinen, Ann-Marie Määttä, Anna-Kaisa Ruotsalainen, Hanna M. Leinonen
Nuclear factor erythroid-2 related factor 2 (Nrf2) is a transcription factor that regulates protection against a wide variety of toxic insults to cells, including cytotoxic cancer chemotherapeutic drugs. Many lung cancer cells harbor a mutation in ei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90bf3aae97f86781220c782bc7ad87cf
https://doi.org/10.1158/0008-5472.c.6503937.v1
https://doi.org/10.1158/0008-5472.c.6503937.v1
Autor:
Anna-Liisa Levonen, Seppo Ylä-Herttuala, Minna U. Kaikkonen, Hanna P. Lesch, Haritha Samaranayake, Jari P. Lappalainen, Jere T. Pikkarainen, Emilia Kansanen, Suvi M. Kuosmanen, Heidi M. Laitinen, Ann-Marie Määttä, Anna-Kaisa Ruotsalainen, Hanna M. Leinonen
PDF file - 57K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e8be17f97492eeb4676915474595fc4
https://doi.org/10.1158/0008-5472.22394055.v1
https://doi.org/10.1158/0008-5472.22394055.v1
Autor:
Anna-Liisa Levonen, Seppo Ylä-Herttuala, Minna U. Kaikkonen, Hanna P. Lesch, Haritha Samaranayake, Jari P. Lappalainen, Jere T. Pikkarainen, Emilia Kansanen, Suvi M. Kuosmanen, Heidi M. Laitinen, Ann-Marie Määttä, Anna-Kaisa Ruotsalainen, Hanna M. Leinonen
PDF file - 324K, The effect of ganciclovir and doxorubicin on ARE activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::551fa5c0ca79e2e61797c8aabe5105b3
https://doi.org/10.1158/0008-5472.22394058.v1
https://doi.org/10.1158/0008-5472.22394058.v1
Autor:
Heidi Hynynen, Haritha Samaranayake, Ann-Marie Määttä, Jere Kurkipuro, Hanna Leinonen, Anniina J. Valkama, Nigel Parker, Venla Olsson, Seppo Ylä-Herttuala, Hanna P. Lesch, Vesa Turkki, Eevi M. Lipponen, Igor Oruetxebarria
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 15, Iss, Pp 63-71 (2019)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
The therapeutic efficacy of a lentiviral vector (LV) expressing the herpes simplex virus thymidine kinase (HSV-TK) was studied in an immunocompetent rat glioblastoma model. Intraperitoneal ganciclovir injections (50 mg/kg/day) were administered for 1
Autor:
Hanna Stedt, Laura Alasaarela, Haritha Samaranayake, Jere Pikkarainen, Ann-Marie Määttä, Ivana Kholová, Aaron S. Parker, Seppo Ylä-Herttuala
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 1, Iss C (2012)
Malignant glioma is a severe cancer with a poor prognosis. Local occurrence and rare metastases of malignant glioma make it a suitable target for gene therapy. Several studies have demonstrated the importance of Src kinase in different cancers. Howev
Externí odkaz:
https://doaj.org/article/8d8aa55ba88c44d9a10476015d1c6dcf
Autor:
Julia Lehtinen, Mari Raki, Kim A Bergström, Päivi Uutela, Katariina Lehtinen, Annukka Hiltunen, Jere Pikkarainen, Huamin Liang, Sari Pitkänen, Ann-Marie Määttä, Raimo A Ketola, Marjo Yliperttula, Thomas Wirth, Arto Urtti
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41410 (2012)
BACKGROUND: Epidermal growth factor receptor (EGFR) is overexpressed in many solid tumor types, such as ovarian carcinoma. Immunoliposome based drug targeting has shown promising results in drug delivery to the tumors. However, the ratio of tumor-to-
Externí odkaz:
https://doaj.org/article/503018bf1f2148a89d56c2f7c458ea89
Autor:
Miia Taavitsainen, Nigel Parker, Jere Kurkipuro, Haritha Samaranayake, Ann-Marie Määttä, Minna U. Kaikkonen, Venla Olsson, Seppo Ylä-Herttuala, Hanna-Riikka Kärkkäinen, Taina Vuorio, Hanna Stedt
Publikováno v:
Journal of Cancer Science & Therapy. 10
Autor:
Thomas Wirth, Galina Dragneva, Taina Vuorio, Hanna P. Lesch, Jere Pikkarainen, Kari J. Airenne, Ann-Marie Määttä, Hanna Stedt, Seppo Ylä-Herttuala, Haritha Samaranayake
Publikováno v:
Human Gene Therapy. 25:942-954
Malignant gliomas (MGs) are highly vascularized, aggressive brain cancers carrying a dismal prognosis. Because of their high vascularity, anti-angiogenic therapy is a potential treatment option. Indeed, the anti-vascular endothelial growth factor (VE