Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ann, Savola"'
Autor:
Dennis Bigg, Simon P. Newman, Chloe Stengel, Sonia Bernetiere, Raphael Dellile, Mark Carlson, José Camara, Eric Ferrandis, Mélissa Le Moing, Nadine Narboux, Vincent Hesry, Delphine Morlais, Olivier Dutruel, Dominique Pons, Pierrick Auvray, Anne-Marie Liberatore, Philip G. Kasprzyk, Hélène Coulomb, Ann Savola Nelson, Béatrice Foll, Gregoire Prevost
Publikováno v:
Molecular Cancer Therapeutics. 7:2426-2434
Tubulin is a validated target for antitumor drugs. However, the effectiveness of these microtubule-interacting agents is limited by the fact that they are substrates for drug efflux pumps (P-glycoprotein) and/or by the acquisition of point mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e8e70f3246309738f21d393b63bf5b
https://doi.org/10.1158/1535-7163.mct-08-0208
https://doi.org/10.1158/1535-7163.mct-08-0208
Autor:
Gregoire Prevost, Pierre Roubert, Daniel W. Zaharevitz, Marie Odile Lonchampt, Samir Attoub, Sophie Chaumeron, Mike Alley, Erik Bruyneel, Hélène Coulomb, Ann Savola, Philip G. Kasprzyk, Susan Holbeck, John Wright, Quang-Dé Nguyen, Patricia Forgez, Christian Gespach, Marie C. Brezak, Mark Bracke, Eric Ferrandis, Marion Huchet, Danièle Demarquay
Publikováno v:
Cancer Research. 66:9227-9234
A large number of hormones and local agonists activating guanine-binding protein-coupled receptors (GPCR) play a major role in cancer progression. Here, we characterize the new imidazo-pyrazine derivative BIM-46174, which acts as a selective inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e35e09855de720491c38a3f5fd371a5
https://doi.org/10.1158/0008-5472.can-05-4205
https://doi.org/10.1158/0008-5472.can-05-4205
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