Zobrazeno 1 - 10
of 722
pro vyhledávání: '"Ann, McMahon"'
Autor:
Vikas A. Tillu, James Rae, Ya Gao, Nicholas Ariotti, Matthias Floetenmeyer, Oleksiy Kovtun, Kerrie-Ann McMahon, Natasha Chaudhary, Robert G. Parton, Brett M. Collins
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Caveolae are spherical nanodomains of the plasma membrane generated by assembly of caveolin and cavin proteins. Here, the authors show that fuzzy electrostatic interactions between caveolin-1 and Cavin1 proteins, combined with membrane lipid interact
Externí odkaz:
https://doaj.org/article/2807bb40181f4244bd067fd1cb562ab3
Autor:
Kerrie-Ann McMahon, David A Stroud, Yann Gambin, Vikas Tillu, Michele Bastiani, Emma Sierecki, Mark E Polinkovsky, Thomas E Hall, Guillermo A Gomez, Yeping Wu, Marie-Odile Parat, Nick Martel, Harriet P Lo, Kum Kum Khanna, Kirill Alexandrov, Roger Daly, Alpha Yap, Michael T Ryan, Robert G Parton
Publikováno v:
eLife, Vol 10 (2021)
Caveolae-associated protein 3 (cavin3) is inactivated in most cancers. We characterized how cavin3 affects the cellular proteome using genome-edited cells together with label-free quantitative proteomics. These studies revealed a prominent role for c
Externí odkaz:
https://doaj.org/article/ec3b060033e84fb68b9e5ab9f7821ac0
Autor:
Kerrie-Ann McMahon, Yeping Wu, Yann Gambin, Emma Sierecki, Vikas A. Tillu, Thomas Hall, Nick Martel, Satomi Okano, Shayli Varasteh Moradi, Jayde E. Ruelcke, Charles Ferguson, Alpha S. Yap, Kirill Alexandrov, Michelle M. Hill, Robert G. Parton
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Caveolae are plasma membrane invaginations containing cavin proteins that are disrupted upon stress stimuli, causing cavin release inside the cell. Here, McMahon et al. identify cavin interacting proteins using proteomic analyses and reveal functions
Externí odkaz:
https://doaj.org/article/7e714ae10b044f39b3b19d07f1029486
Autor:
Zherui Xiong, Harriet P Lo, Kerrie-Ann McMahon, Nick Martel, Alun Jones, Michelle M Hill, Robert G Parton, Thomas E Hall
Publikováno v:
eLife, Vol 10 (2021)
Protein interaction networks are crucial for complex cellular processes. However, the elucidation of protein interactions occurring within highly specialised cells and tissues is challenging. Here, we describe the development, and application, of a n
Externí odkaz:
https://doaj.org/article/25e12cf3bd9940f393a66eb84cdd6fd6
Publikováno v:
The Journal of Health Design, Vol 5, Iss 3 (2020)
This retrospective study compared EOScalc clinical recommendations based on neonatal early onset sepsis (EOS) predictors and the infant’s clinical presentation with actual treatment decided upon and administered by treating clinicians.
Externí odkaz:
https://doaj.org/article/ecf7eee1fdda46aaa6ebfcd22e430940
Autor:
Ann, McMahon
Publikováno v:
Journal of Research in Nursing. 27:681-684
Caveolae are small membrane invaginations that generally are stably attached to the plasma membrane. Their release is believed to depend on the GTPase dynamin 2 (Dyn2), in analogy with its role in fission of clathrin-coated vesicles. The mechanistic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd4a82ecb59b8e386cdd18304115728
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-208218
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-208218
Autor:
Ann, McMahon
Publikováno v:
Journal of Research in Nursing. 27:501-503
Autor:
Sachini Fonseka, Benjamin D. Weger, Meltem Weger, Nick Martel, Thomas E. Hall, Shayli Varasteh Moradi, Christian H. Gabriel, Achim Kramer, Charles Ferguson, Manuel A. Fernández-Rojo, Kirill Alexandrov, Oliver Rawashdeh, Kerrie-Ann McMahon, Frederic Gachon, Robert G Parton
Caveolae are specialized invaginations of the plasma membrane that are formed by the co-assembly of caveolin integral membrane proteins and a cytoplasmic cavin coat complex. Previous work has proposed an interaction of the cavin coat protein, CAVIN3,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c3536061fcaaa34d293da444415f349
https://doi.org/10.1101/2022.10.10.511681
https://doi.org/10.1101/2022.10.10.511681
Publikováno v:
Current Opinion in Cell Biology. 71:7-14
Caveolae are abundant plasma membrane pits formed by the coordinated action of peripheral and integral membrane proteins and membrane lipids. Here, we discuss recent studies that are starting to provide a glimpse of how filamentous cavin proteins, me