Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Ann, Chahroudi"'
Publikováno v:
Retrovirology, Vol 21, Iss 1, Pp 1-9 (2024)
Abstract Despite the efficacy of antiretroviral therapy (ART) in reducing the global incidence of vertical HIV transmissions, more than 120,000 children are still infected with the virus each year. Since ART cannot clear the HIV reservoir that is est
Externí odkaz:
https://doaj.org/article/a8f443a9e5db4b7e861ddde9fc4bad59
Autor:
Ellie Mainou, Stella J. Berendam, Veronica Obregon-Perko, Emilie A. Uffman, Caroline T. Phan, George M. Shaw, Katharine J. Bar, Mithra R. Kumar, Emily J. Fray, Janet M. Siliciano, Robert F. Siliciano, Guido Silvestri, Sallie R. Permar, Genevieve G. Fouda, Janice McCarthy, Ann Chahroudi, Jessica M. Conway, Cliburn Chan
Publikováno v:
Epidemics, Vol 48, Iss , Pp 100780- (2024)
While the benefits of early antiretroviral therapy (ART) initiation in perinatally infected infants are well documented, early initiation is not always possible in postnatal pediatric HIV infections. The timing of ART initiation is likely to affect t
Externí odkaz:
https://doaj.org/article/60d2aef43b0643d1af9bb0c95351b590
Autor:
Sedem Dankwa, Christina Kosman, Maria Dennis, Elena E Giorgi, Kenneth Vuong, Ioanna Pahountis, Ashley Garza, Christian Binuya, Janice McCarthy, Bryan T Mayer, Julia T Ngo, Chiamaka A Enemuo, Diane G Carnathan, Sherry Stanfield-Oakley, Stella J Berendam, Carolyn Weinbaum, Kathleen Engelman, Diogo M Magnani, Cliburn Chan, Guido Ferrari, Guido Silvestri, Rama R Amara, Ann Chahroudi, Sallie R Permar, Genevieve G Fouda, Ria Goswami
Publikováno v:
PLoS ONE, Vol 19, Iss 11, p e0312411 (2024)
To eliminate vertical HIV transmission and achieve therapy-free viral suppression among children living with HIV, novel strategies beyond antiretroviral therapy (ART) are necessary. Our group previously identified a triple broadly neutralizing antibo
Externí odkaz:
https://doaj.org/article/67249a617a5941c98087a2a5528cf93f
Autor:
Samuel Druzak, Elizabeth Iffrig, Blaine R. Roberts, Tiantian Zhang, Kirby S. Fibben, Yumiko Sakurai, Hans P. Verkerke, Christina A. Rostad, Ann Chahroudi, Frank Schneider, Andrew Kam Ho Wong, Anne M. Roberts, Joshua D. Chandler, Susan O. Kim, Mario Mosunjac, Marina Mosunjac, Rachel Geller, Igor Albizua, Sean R. Stowell, Connie M. Arthur, Evan J. Anderson, Anna A. Ivanova, Jun Ahn, Xueyun Liu, Kristal Maner-Smith, Thomas Bowen, Mirko Paiardini, Steve E. Bosinger, John D. Roback, Deanna A. Kulpa, Guido Silvestri, Wilbur A. Lam, Eric A. Ortlund, Cheryl L. Maier
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
In this work, authors take a multiomics and microfluidics-based approach to elucidate the mechanism of endothelial damage in critical illness associated with SARS-CoV-2.
Externí odkaz:
https://doaj.org/article/f453c7377ff248be8d16d63d8c87445a
Autor:
Yuyang Tang, Antoine Chaillon, Sara Gianella, Lilly M. Wong, Dajiang Li, Theresa L. Simermeyer, Magali Porrachia, Caroline Ignacio, Brendon Woodworth, Daniel Zhong, Jiayi Du, Eduardo de la Parra Polina, Jennifer Kirchherr, Brigitte Allard, Matthew L. Clohosey, Matt Moeser, Amy L. Sondgeroth, Gregory D. Whitehill, Vidisha Singh, Amir Dashti, Davey M. Smith, Joseph J. Eron, Katherine J. Bar, Ann Chahroudi, Sarah B. Joseph, Nancie M. Archin, David M. Margolis, Guochun Jiang
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 12 (2023)
Brain microglia (MG) may serve as a human immunodeficiency virus 1 (HIV) reservoir and ignite rebound viremia following cessation of antiretroviral therapy (ART), but they have yet to be proven to harbor replication-competent HIV. Here, we isolated b
Externí odkaz:
https://doaj.org/article/2b445d2797e54b559239027e8348ce19
Publikováno v:
Frontiers in Virology, Vol 2 (2023)
The advancement of science has been a collective effort and benefits from a diversity of views and gender representation. However, support for and recognition of women in science is often insufficient. Despite historically being marginalized by the s
Externí odkaz:
https://doaj.org/article/d8b9204af634471e94e0197c87c34a08
Autor:
Cassie G. Ackerley, S. Abigail Smith, Phillip M. Murray, Praveen K. Amancha, Robert A. Arthur, Zhengyi Zhu, Ann Chahroudi, Rama R. Amara, Yi-Juan Hu, Colleen F. Kelley
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Young men who have sex with men (YMSM) represent a particularly high-risk group for HIV acquisition in the US, despite similarly reported rates of sexual activity as older, adult MSM (AMSM). Increased rates of HIV infection among YMSM compared to AMS
Externí odkaz:
https://doaj.org/article/864981ed02b540d9ae014ff49aad67ec
Autor:
Jennifer K. Frediani, Joshua M. Levy, Anuradha Rao, Leda Bassit, Janet Figueroa, Miriam B. Vos, Anna Wood, Robert Jerris, Van Leung-Pineda, Mark D. Gonzalez, Beverly B. Rogers, Maud Mavigner, Raymond F. Schinazi, Nils Schoof, Jesse J. Waggoner, Russell R. Kempker, Paulina A. Rebolledo, Jared W. O’Neal, Cheryl Stone, Ann Chahroudi, Claudia R. Morris, Allie Suessmith, Julie Sullivan, Sarah Farmer, Amanda Foster, John D. Roback, Thanuja Ramachandra, CaDeidre Washington, Kristie Le, Maria C. Cordero, Annette Esper, Eric J. Nehl, Yun F. Wang, Erika A. Tyburski, Greg S. Martin, Wilbur A. Lam
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract While there has been significant progress in the development of rapid COVID-19 diagnostics, as the pandemic unfolds, new challenges have emerged, including whether these technologies can reliably detect the more infectious variants of concer
Externí odkaz:
https://doaj.org/article/30016094be9f470888a58161d2407fd5
Autor:
Stella J. Berendam, Ashley N. Nelson, Bhrugu Yagnik, Ria Goswami, Tiffany M. Styles, Margaret A. Neja, Caroline T. Phan, Sedem Dankwa, Alliyah U. Byrd, Carolina Garrido, Rama R. Amara, Ann Chahroudi, Sallie R. Permar, Genevieve G. Fouda
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Early initiation of antiretroviral therapy (ART) significantly improves clinical outcomes and reduces mortality of infants/children living with HIV. However, the ability of infected cells to establish latent viral reservoirs shortly after infection a
Externí odkaz:
https://doaj.org/article/58c873b9fd734cfe843c751bcee74119
Autor:
Giuseppe Rubens Pascucci, Elena Morrocchi, Chiara Pighi, Arianna Rotili, Alessia Neri, Chiara Medri, Giulio Olivieri, Marco Sanna, Gianmarco Rasi, Deborah Persaud, Ann Chahroudi, Mathias Lichterfeld, Eleni Nastouli, Caterina Cancrini, Donato Amodio, Paolo Rossi, Nicola Cotugno, Paolo Palma
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 888 (2023)
Most of the current assays directed at the investigation of HIV reactivation are based on cultures of infected cells such as Peripheral Blood Mononuclear Cells (PBMCs) or isolated CD4+ T cells, stimulated in vitro with different activator molecules.
Externí odkaz:
https://doaj.org/article/dc66d2f161da44098e319b2590102f35