Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ankita Goradia"'
Autor:
Zhen Liang, Alistair M Chalk, Scott Taylor, Ankita Goradia, Jacki E Heraud‐Farlow, Carl R Walkley
Publikováno v:
EMBO reports. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcadd87b869b2dca8c0172186b587177
https://doi.org/10.15252/embr.202255835
https://doi.org/10.15252/embr.202255835
Adenosine to inosine editing (A-to-I) in regions of double stranded RNA (dsRNA) is mediated by adenosine deaminase acting on RNA 1 (ADAR1) or ADAR2. ADAR1 and A-to-I editing levels are increased in many human cancers. It is not established if elevate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::967207b95378cc13f983cb4cfd55936f
https://doi.org/10.1101/2023.01.29.526130
https://doi.org/10.1101/2023.01.29.526130
Autor:
Shi-Bin Hu, Jacki Heraud-Farlow, Tao Sun, Zhen Liang, Ankita Goradia, Scott Taylor, Carl R Walkley, Jin Billy Li
Publikováno v:
bioRxiv
SummaryEffective immunity requires the innate immune system to distinguish foreign (non-self) nucleic acids from cellular (self) nucleic acids. Cellular double-stranded RNAs (dsRNAs) are edited by the RNA editing enzyme ADAR1 to prevent their dsRNA s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a473c78b5117f8d848866cc5c040021f
https://europepmc.org/articles/PMC9900771/
https://europepmc.org/articles/PMC9900771/
SummaryADAR1 mediated A-to-I RNA editing is a self/non-self discrimination mechanism for cellular double stranded RNAs. ADAR mutations are one cause of Aicardi-Goutières Syndrome, an inherited paediatric encephalopathy, broadly classed as a “Type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f83b09fbd9fe6f07001b28ffb0ea022
https://doi.org/10.1101/2022.06.24.497437
https://doi.org/10.1101/2022.06.24.497437
Autor:
Martina Fuchsberger, Ankita Goradia, Tracy A. Willson, Robyn Starr, Anne M. Verhagen, Adam P Uldrich, Lei Shong Lau, Mark J. Smyth, Warren S. Alexander
Publikováno v:
The Journal of Immunology. 183:4537-4544
Suppressor of cytokine signaling (SOCS)-1 is a critical inhibitor of IFN-γ signal transduction in vivo, but the precise biochemical mechanism of action of SOCS-1 is unclear. Studies in vitro have shown that SOCS-1 binds to Jaks and inhibits their ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf2d8ee3f42fef182a7a366e3af18cb1
https://doi.org/10.4049/jimmunol.0901010
https://doi.org/10.4049/jimmunol.0901010
Autor:
Warren S. Alexander, Robyn Starr, Anne M Verhagen, Janelle E. Collinge, Hayley A Croom, Morgan E. Wallace, Mhairi J Maxwell, Donald Metcalf, Douglas J. Hilton, Ankita Goradia, Margaret L. Hibbs, Benjamin T. Kile, Sarah Jones
Publikováno v:
The Journal of Immunology. 182:2020-2029
Lyn kinase, a member of the Src family of tyrosine kinases, functions as both a positive and negative regulator of B cell activation. In the absence of Lyn, BCR signaling is unregulated, leading to perturbed B cell development, hyperactive B cells, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abbb8f445f32e02efa153be52a37a4a9
https://doi.org/10.4049/jimmunol.0803127
https://doi.org/10.4049/jimmunol.0803127
Autor:
Alvin J. M. Ng, Emma Baker, Louise E. Purton, Alistair M. Chalk, Carl R. Walkley, Meaghan Wall, Patricia W. M. Ho, Brain J.J. Liddicoat, Ross A. Dickins, Anthony J. Mutsaers, Ankita Goradia, Megan R. Russell, John Slavin, T. John Martin
Osteosarcoma is the most common primary cancer of bone and one that predominantly affects children and adolescents. Osteoblastic osteosarcoma represents the major subtype of this tumor, with approximately equal representation of fibroblastic and chon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddaabeb9ae40b1b7601929ef15adc634
https://acuresearchbank.acu.edu.au/item/87ww4/modeling-distinct-osteosarcoma-subtypes-in-vivo-using-cre-lox-and-lineage-restricted-transgenic-shrna
https://acuresearchbank.acu.edu.au/item/87ww4/modeling-distinct-osteosarcoma-subtypes-in-vivo-using-cre-lox-and-lineage-restricted-transgenic-shrna
Autor:
Patricia W. M. Ho, John Slavin, T. John Martin, Megan R. Russell, Carl R. Walkley, Alistair M. Chalk, Ross A. Dickins, Ankita Goradia
Publikováno v:
Cancer Research. 74:A54-A54
Osteosarcoma (OS) is the most common tumor of bone. Parathyroid hormone (PTH) is a major endocrine regulator of skeletal development and homeostasis. We have sought to understand the contribution of PTH and parathyroid hormone related protein (PTHrP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eee3b7a90a9cfe26e2bad7106e9e08d8
https://doi.org/10.1158/1538-7445.pedcan-a54
https://doi.org/10.1158/1538-7445.pedcan-a54
Autor:
Anne Verhagen, Morgan Wallace, Ankita Goradia, Sarah Jones, Hayley Croom, Donald Metcalf, Janelle Collinge, Mhairi Maxwell, Margaret Hibbs, Warren Alexander, Douglas Hilton, Benjamin Kile, Robyn Starr
Publikováno v:
Monash University
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b0c74f462ca26fcb23b28980987a85a5
https://research.monash.edu/en/publications/e3e86894-01a2-46af-b65e-ccc7da55c597
https://research.monash.edu/en/publications/e3e86894-01a2-46af-b65e-ccc7da55c597
Autor:
Patricia W. M. Ho, Ross A. Dickins, Kristi M Milley, John Slavin, Blessing Crimeen-Irwin, Janine A. Danks, Carl R. Walkley, Emma Baker, Mannu K Walia, Alistair M. Chalk, Megan R. Russell, Thomas J. Martin, Ankita Goradia
Publikováno v:
Europe PubMed Central
Osteosarcoma (OS) is the most common cancer of bone. Parathyroid hormone (PTH) regulates calcium homeostasis and bone development, while the paracrine/autocrine PTH-related protein (PTHrP) has central roles in endochondral bone formation and bone rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5068382f94a8fa4644127fe0732e0063
http://europepmc.org/abstract/med/25043296
http://europepmc.org/abstract/med/25043296