Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ankit Mahendra"'
Autor:
Ankit Mahendra, Aftabul Haque, Ponraj Prabakaran, Brian C. Mackness, Thomas P. Fuller, Xiaohua Liu, Sagar V. Kathuria, Yui-Hsi Wang, Nilesh Amatya, Xiaocong Yu, Joern Hopke, Dietmar Hoffmann, Eva Bric-Furlong, Ningning Zhang, Hyun-Suk Cho, Ruijun Zhang, Jose Sancho, Jacqueline Saleh, Sambasiva P. Rao, Maria Wendt, Partha S. Chowdhury
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
The authors developed a methodology for bulk enrichment of antigen-specific B cells to improve the diversity of antibody sequences and increase the number of functional antigen-specific antibodies coming from different antibody generation platforms.
Externí odkaz:
https://doaj.org/article/52ce13cfecd7433fa59e55c134afee54
Autor:
Gabrielle Romain, Paolo Strati, Ali Rezvan, Mohsen Fathi, Irfan N. Bandey, Jay R T. Adolacion, Darren Heeke, Ivan Liadi, Mario L. Marques-Piubelli, Luisa M. Solis, Ankit Mahendra, Francisco Vega, Laurence J.N. Cooper, Harjeet Singh, Mike Mattie, Adrian Bot, Sattva S. Neelapu, Navin Varadarajan
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 17 (2022)
The in vivo persistence of adoptively transferred T cells is predictive of antitumor response. Identifying functional properties of infused T cells that lead to in vivo persistence and tumor eradication has remained elusive. We profiled CD19-specific
Externí odkaz:
https://doaj.org/article/22541142eb294d1693d8dcd42d53759f
Autor:
Ankit Mahendra, Ivan Peyron, Cécile Dollinger, Laurent Gilardin, Meenu Sharma, Bharath Wootla, Séverine Padiolleau-Lefevre, Alain Friboulet, Didier Boquet, Christophe Legendre, Srinivas V Kaveri, Olivier Thaunat, Sébastien Lacroix-Desmazes
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70731 (2013)
Catalytic antibodies are immunoglobulins endowed with enzymatic activity. Catalytic IgG has been reported in several human autoimmune and inflammatory diseases. In particular, low levels of catalytic IgG have been proposed as a prognostic marker for
Externí odkaz:
https://doaj.org/article/a5d66cc79cb3401e9b2f1c3fbe9e1044
Autor:
Gabrielle Romain, Paolo Strati, Ali Rezvan, Mohsen Fathi, Irfan N Bandey, Jay R T Adolacion, Darren Heeke, Ivan Liadi, Mario L Marques-Piubelli, Luisa M. Solis, Ankit Mahendra, Francisco Vega, Laurence J.N. Cooper, Harjeet Singh, Mike Mattie, Adrian Bot, Sattva Neelapu, Navin Varadarajan
The in vivo persistence of adoptively transferred T cells is predictive of anti-tumor response. Identifying functional properties of infused T cells that lead to in vivo persistence and tumor eradication has remained elusive. We profiled CD19-specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::921728699a9ff2dc9e9101e827d2c8e7
https://doi.org/10.1101/2022.02.11.479825
https://doi.org/10.1101/2022.02.11.479825
Autor:
Colin D. Paul, Navin Varadarajan, Kristen M. Manto, Stuart S. Martin, Daniel J. Shea, Panagiotis Mistriotis, Konstantinos Konstantopoulos, Keyata Thompson, Andreas C. Chai, Michele Vitolo, Christopher L. Yankaskas, Vivek K. Bajpai, Aikaterini Kontrogianni-Konstantopoulos, Ankit Mahendra
Publikováno v:
Nature biomedical engineering
The challenge of predicting which patients with breast cancer will develop metastases leads to the overtreatment of patients with benign disease and to the inadequate treatment of the aggressive cancers. Here, we report the development and testing of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb3b414f3d611af99d404573e65ad79d
https://pubmed.ncbi.nlm.nih.gov/31175331
https://pubmed.ncbi.nlm.nih.gov/31175331
Autor:
Sandeep K. Agarwal, Ankit Mahendra, Daechan Park, Cristian Coarfa, Sanam Soomro, Jay R Adolacion, Shaza Abnouf, Peng Qiu, Keith C. Wanzeck, S. Louis Bridges, Xingyu Yang, Jason Roszik, Gabrielle Romain, Chandra Mohan, Amita Aggarwal, Navin Varadarajan
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 71(4)
Objective To obtain the comprehensive transcriptome profile of human citrulline-specific B cells from patients with rheumatoid arthritis (RA). Methods Citrulline- and hemagglutinin-specific B cells were sorted by flow cytometry using peptide-streptav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d11588dc42e7384a5f9d7ee58d835ba
https://pubmed.ncbi.nlm.nih.gov/30679818
https://pubmed.ncbi.nlm.nih.gov/30679818
Autor:
Shaza Abnouf, Keith C. Wanzeck, Peng Qiu, Chandra Mohan, S. Louis Bridges, Sandeep K. Agarwal, Navin Varadarajan, Cristian Coarfa, Sanam Soomro, Amita Aggarwal, Gabrielle Romain, Daechan Park, Jason Roszik, Ankit Mahendra, Adolacion, Xingyu Yang
Although the contribution of B-cell derived autoreactive antibodies to rheumatoid arthritis (RA) has been studied extensively, the autoantibody-independent roles of B cells in the progression of the disease is not well-defined. Here we present the fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c78b26facf9ca7b0c5448635f6739bd0
https://doi.org/10.1101/144121
https://doi.org/10.1101/144121
Autor:
Frederic Davi, Srinivas V. Kaveri, Myriam Boudjoghra, Jordan D. Dimitrov, Bagirath Gangadharan, Ankit Mahendra, Sébastien André, Cyril Planchais, Maxime Lecerf, Sébastien Lacroix-Desmazes
Publikováno v:
Molecular Immunology. 60:54-61
Polyreactive antibodies represent a significant fraction of immune repertoires and play an important role in the immune defense and immune homeostasis. Polyreactive B-cell receptors (BCR), however, are frequently expressed by B-cell lymphomas. It was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8614c29f7197ade9a7758b2ab837dc5c
https://doi.org/10.1016/j.molimm.2014.03.009
https://doi.org/10.1016/j.molimm.2014.03.009
Autor:
Konrad Gabrusiewicz, Ankit Mahendra, Xingyue An, Melisa Martinez-Paniagua, Robiya Joseph, Navin Varadarajan, Sendurai A. Mani, Jay R Adolacion, Mohsen Fathi, Sujash S. Chatterjee
Publikováno v:
Cancer Research. 79:2907-2907
Decades of research on exosomes, nano-sized vesicles secreted by cells, have revealed novel roles of these vesicles in the formation of pre-metastasis niches that enhances the migration of tumor cells to those sites. Paradoxically, more recent work h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29a9bcc19261c91d86b00fe625d6e807
https://doi.org/10.1158/1538-7445.am2019-2907
https://doi.org/10.1158/1538-7445.am2019-2907
Autor:
Xingyue An, Gabrielle Romain, Melisa Martinez-Paniagua, Irfan N Bandey, Jay R T Adolacion, Mohsen Fathi, Ivan Liadi, Fatemeh Sadeghi, Ankit Mahendra, Amit Amritkar, Badrinath Roysam, Harjeet Singh, Laurence J Cooper, Navin Varadarajan
Publikováno v:
The Journal of Immunology. 202:134.2-134.2
T cells engineered to express chimeric antigen receptor (CAR) targeting CD19 have shown promising clinical responses in patients with certain hematologic malignancies, however, it is desirable to be able to enrich cells with enhanced anti-tumor effic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae324e9f8e6992bf059a0ab8eb55b306
https://doi.org/10.4049/jimmunol.202.supp.134.2
https://doi.org/10.4049/jimmunol.202.supp.134.2