Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ankit Kumar, Tamta"'
Autor:
Perumal Arumugam Desingu, Sneha Mishra, Lavanya Dindi, Shalini Srinivasan, Raju S. Rajmani, Venkatraman Ravi, Ankit Kumar Tamta, Sukanya Raghu, Krishnega Murugasamy, Anwit Shriniwas Pandit, Nagalingam R. Sundaresan
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113103- (2023)
Summary: Japanese encephalitis (JE) is a vector-borne viral disease that causes acute encephalitis in children. Although vaccines have been developed against the JE virus (JEV), no effective antiviral therapy exists. Our study shows that inhibition o
Externí odkaz:
https://doaj.org/article/89e68ecdbcfd445eaf5e8324c18f07ad
Autor:
Sneha Mishra, Claudia Cosentino, Ankit Kumar Tamta, Danish Khan, Shalini Srinivasan, Venkatraman Ravi, Elena Abbotto, Bangalore Prabhashankar Arathi, Shweta Kumar, Aditi Jain, Anand S. Ramaian, Shruti M. Kizkekra, Raksha Rajagopal, Swathi Rao, Swati Krishna, Ninitha Asirvatham-Jeyaraj, Elizabeth R. Haggerty, Dafne M. Silberman, Irwin J. Kurland, Ravindra P. Veeranna, Tamilselvan Jayavelu, Santina Bruzzone, Raul Mostoslavsky, Nagalingam R. Sundaresan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
Chronic stress induces skeletal muscle atrophy via upregulation of glucocorticoid levels. Here, the authors show that SIRT6 transcriptionally regulates glucocorticoid-induced muscle atrophy by modulating IGF/PI3K/AKT signalling.
Externí odkaz:
https://doaj.org/article/d4cbf3bac7a14798ba51e0d8aeaeb195
Autor:
Ankit Kumar, Tamta, Bhoomika, Shivanaiah, Sunayana, Ningaraju, Arathi Bangalore, Prabhashankar, Nagalingam Ravi, Sundaresan
Publikováno v:
Current Protocols. 2
Besides genetic disorders, skeletal muscle atrophy mainly occurs as a consequence of underlying conditions such as prolonged inactivity, aging, and metabolic diseases, ultimately contributing to the risk of disability. Disturbances in cellular and mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a441b0cd99d465e65df6c7cbe099763
https://doi.org/10.1002/cpz1.616
https://doi.org/10.1002/cpz1.616
Autor:
Edward A Gonzalez, Jayadevan Parvathy, Raul Mostoslavsky, Subhajit Dasgupta, Ninitha Asirvatham-Jeyaraj, Danish Khan, Jean-Pierre Etchegaray, Raksha Rajagopal, Venkatraman Ravi, Nagalingam R. Sundaresan, Ankit Kumar Tamta, Himani Tandon, Sneha Mishra, Prasanna Simha Mohan Rao, Arvind Singh Bhati, Ullas Kolthur-Seetharam, Tarannum Ara, Swati Krishna, Narayanaswamy Srinivasan, Sukanya Raghu
Publikováno v:
Cell reports
SUMMARY Pathological lipid accumulation is often associated with enhanced uptake of free fatty acids via specific transporters in cardiomyocytes. Here, we identify SIRT6 as a critical transcriptional regulator of fatty acid transporters in cardiomyoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e21d71a7ba00b2b61c76a9104b2a5ed
http://europepmc.org/articles/PMC8190874
http://europepmc.org/articles/PMC8190874
Autor:
Aishwarya Raghuraman, S. V. N. Rao, Sangeeta Maity, Shamik Majumdar, Perumal Arumugam Desingu, Aditi Jain, Mohsen Sarikhani, S.A. Kumar, Kondapalli Mrudula Spurthi, Danish Khan, Sneha Mishra, Nagalingam R. Sundaresan, Rosa J. Samuel, Shikha Yadav, Ishwar Singh, Ankit Kumar Tamta, Dipankar Nandi, S. G. Ramachandra
Publikováno v:
The Journal of biological chemistry. 293(34)
Toll-like receptors (TLRs) are a family of pattern-recognition receptors involved in innate immunity. Previous studies have shown that TLR2 inhibition protects the heart from acute stress, including myocardial infarction and doxorubicin-induced cardi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::925c02b86c732d2befe241629e9ebcc9
https://pubmed.ncbi.nlm.nih.gov/29929978
https://pubmed.ncbi.nlm.nih.gov/29929978
Autor:
Anwit S. Pandit, Danish Khan, Mrudula S. Kondapalli, S. V. N. Rao, Sangeeta Maity, Venkatraman Ravi, Perumal Arumugam Desingu, Meena Inbaraj, Nagalingam R. Sundaresan, Ankit Kumar Tamta, Mohsen Sarikhani, Aditi Jain, S.A. Kumar, Sneha Mishra
Publikováno v:
The Journal of biological chemistry. 293(14)
Heart failure is an aging-associated disease that is the leading cause of death worldwide. Sirtuin family members have been largely studied in the context of aging and aging-associated diseases. Sirtuin 2 (SIRT2) is a cytoplasmic protein in the famil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a749b9967a9afc3ae517b47eade67b3e
https://pubmed.ncbi.nlm.nih.gov/29440391
https://pubmed.ncbi.nlm.nih.gov/29440391
Autor:
Ankit Kumar Tamta, Anwit S. Pandit, S.A. Kumar, Mohsen Sarikhani, Sathees C. Raghavan, Danish Khan, Sneha Mishra, Shruti M. Kizkekra, Nagalingam R. Sundaresan, Perumal Arumugam Desingu
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Cardiomyopathy is one of the characteristic features of cancer. In this study, we establish a suitable model to study breast cancer-induced cardiomyopathy in mice. We used Ehrlich Ascites Carcinoma cells to induce subcutaneous tumor in 129/SvJ mice a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51dba09d7adbdcf9cfd8a98fc0ea1a9b
https://pubmed.ncbi.nlm.nih.gov/29618792
https://pubmed.ncbi.nlm.nih.gov/29618792