Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Ankit Dwivedi"'
Autor:
Gail E. Potter, Viviane Callier, Biraj Shrestha, Sudhaunshu Joshi, Ankit Dwivedi, Joana C. Silva, Matthew B. Laurens, Dean A. Follmann, Gregory A. Deye
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-17 (2023)
Abstract Background Early phase malaria vaccine field trials typically measure malaria infection by PCR or thick blood smear microscopy performed on serially sampled blood. Vaccine efficacy (VE) is the proportion reduction in an endpoint due to vacci
Externí odkaz:
https://doaj.org/article/053e346859e2446086ce6e39b53fa97f
Autor:
Diana Moita, Teresa G. Maia, Miguel Duarte, Carolina M. Andrade, Inês S. Albuquerque, Ankit Dwivedi, Joana C. Silva, Lilia González-Céron, Chris J. Janse, António M. Mendes, Miguel Prudêncio
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-9 (2022)
Abstract Two malaria parasite species, Plasmodium falciparum (Pf) and P. vivax (Pv) are responsible for most of the disease burden caused by malaria. Vaccine development against this disease has focused mainly on Pf. Whole-sporozoite (WSp) vaccinatio
Externí odkaz:
https://doaj.org/article/e826d5ba7493466aa874bf76000cc79f
Autor:
Gillian Mbambo, Ankit Dwivedi, Olukemi O. Ifeonu, James B. Munro, Biraj Shrestha, Robin E. Bromley, Theresa Hodges, Ricky S. Adkins, Bourema Kouriba, Issa Diarra, Amadou Niangaly, Abdoulaye K. Kone, Drissa Coulibaly, Karim Traore, Amagana Dolo, Mahamadou A. Thera, Matthew B. Laurens, Ogobara K. Doumbo, Christopher V. Plowe, Andrea A. Berry, Mark Travassos, Kirsten E. Lyke, Joana C. Silva
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionHost gene and protein expression impact susceptibility to clinical malaria, but the balance of immune cell populations, cytokines and genes that contributes to protection, remains incompletely understood. Little is known about the determi
Externí odkaz:
https://doaj.org/article/4be637d5b54b4a7cbb6926e457c1deca
Autor:
Thomas C. Stabler, Ankit Dwivedi, Biraj Shrestha, Sudhaunshu Joshi, Tobias Schindler, Amed Ouattara, Guillermo A. García, Claudia Daubenberger, Joana C. Silva
Publikováno v:
Malaria Journal, Vol 21, Iss 1, Pp 1-17 (2022)
Abstract Background The ability of malaria rapid diagnostic tests (RDTs) to effectively detect active infections is being compromised by the presence of malaria strains with genomic deletions at the hrp2 and hrp3 loci, encoding the antigens most comm
Externí odkaz:
https://doaj.org/article/7f04ab0869a14203a0550948bbf8e570
Autor:
Joana C. Silva, Ankit Dwivedi, Kara A. Moser, Mahamadou S. Sissoko, Judith E. Epstein, Sara A. Healy, Kirsten E. Lyke, Benjamin Mordmüller, Peter G. Kremsner, Patrick E. Duffy, Tooba Murshedkar, B. Kim Lee Sim, Thomas L. Richie, Stephen L. Hoffman
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Here the authors show that controlled human malaria infection with a Brazilian parasite highly divergent from vaccine and West African field strains can provide estimates of vaccine efficacy in Mali, and could replace field testing, streamlining vacc
Externí odkaz:
https://doaj.org/article/8adef3faef374367ad0d7275f5f65245
Autor:
Alvaro Molina-Cruz, Nadia Raytselis, Roxanne Withers, Ankit Dwivedi, Peter D. Crompton, Boubacar Traore, Giovanna Carpi, Joana C. Silva, Carolina Barillas-Mury
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-6 (2021)
Molina-Cruz et al. analyzed 4,971 sequences of the Plasmodium falciparum Pfs47 gene and identified a combination of two SNP haplotypes highly correlated with geographic origin and transmission potential by mosquito vectors. A simple High-Resolution M
Externí odkaz:
https://doaj.org/article/fc42e52755fa4bd685f6c6320aeedb3b
Autor:
Jenna Oberstaller, Linda Zoungrana, Carl D. Bannerman, Samira Jahangiri, Ankit Dwivedi, Joana C. Silva, John H. Adams, Shannon Takala-Harrison
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 16, Iss , Pp 119-128 (2021)
Resistance to antimalarial drugs, and in particular to the artemisinin derivatives and their partner drugs, threatens recent progress toward regional malaria elimination and eventual global malaria eradication. Population-level studies utilizing whol
Externí odkaz:
https://doaj.org/article/a58701cf737f4955b68ba603aad8add8
Autor:
Emily M. Stucke, Antoine Dara, Ankit Dwivedi, Theresa K. Hodges, Sandra Ott, Drissa Coulibaly, Abdoulaye K. Koné, Karim Traoré, Bouréima Guindo, Bourama M. Tangara, Amadou Niangaly, Modibo Daou, Issa Diarra, Youssouf Tolo, Mody Sissoko, Luke J. Tallon, Lisa Sadzewicz, Albert E. Zhou, Matthew B. Laurens, Amed Ouattara, Bourema Kouriba, Ogobara K. Doumbo, Shannon Takala-Harrison, David Serre, Christopher V. Plowe, Mahamadou A. Thera, Mark A. Travassos, Joana C. Silva
Publikováno v:
mSystems, Vol 6, Iss 6 (2021)
ABSTRACT var genes encode Plasmodium falciparum erythrocyte membrane protein-1 (PfEMP1) antigens. These highly diverse antigens are displayed on the surface of infected erythrocytes and play a critical role in immune evasion and sequestration of infe
Externí odkaz:
https://doaj.org/article/68627110cf9b45df9baabebd0ad00fb8
Autor:
Kara A. Moser, Elliott F. Drábek, Ankit Dwivedi, Emily M. Stucke, Jonathan Crabtree, Antoine Dara, Zalak Shah, Matthew Adams, Tao Li, Priscila T. Rodrigues, Sergey Koren, Adam M. Phillippy, James B. Munro, Amed Ouattara, Benjamin C. Sparklin, Julie C. Dunning Hotopp, Kirsten E. Lyke, Lisa Sadzewicz, Luke J. Tallon, Michele D. Spring, Krisada Jongsakul, Chanthap Lon, David L. Saunders, Marcelo U. Ferreira, Myaing M. Nyunt, Miriam K. Laufer, Mark A. Travassos, Robert W. Sauerwein, Shannon Takala-Harrison, Claire M. Fraser, B. Kim Lee Sim, Stephen L. Hoffman, Christopher V. Plowe, Joana C. Silva
Publikováno v:
Genome Medicine, Vol 12, Iss 1, Pp 1-17 (2020)
Abstract Background Plasmodium falciparum (Pf) whole-organism sporozoite vaccines have been shown to provide significant protection against controlled human malaria infection (CHMI) in clinical trials. Initial CHMI studies showed significantly higher
Externí odkaz:
https://doaj.org/article/da4c7040d45149b5b3b71fa0feb8a7a6
Autor:
Zalak Shah, Myo T Naung, Kara A Moser, Matthew Adams, Andrea G Buchwald, Ankit Dwivedi, Amed Ouattara, Karl B Seydel, Don P Mathanga, Alyssa E Barry, David Serre, Miriam K Laufer, Joana C Silva, Shannon Takala-Harrison
Publikováno v:
PLoS Genetics, Vol 17, Iss 5, p e1009576 (2021)
Individuals acquire immunity to clinical malaria after repeated Plasmodium falciparum infections. Immunity to disease is thought to reflect the acquisition of a repertoire of responses to multiple alleles in diverse parasite antigens. In previous stu
Externí odkaz:
https://doaj.org/article/f7a083e36c25497f819185db277fe57c