Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Ankie Poutsma"'
Autor:
Vera Manders, Allerdien Visser, Remco Keijser, Naomi Min, Ankie Poutsma, Joyce Mulders, Tarah van den Berkmortel, Marjolein Hortensius, Aldo Jongejan, Eva Pajkrt, Erik A. Sistermans, Daoud Sie, Myron G. Best, Tom Würdinger, Marjon de Boer, Gijs Afink, Cees Oudejans
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Using genome-wide transcriptome analysis by RNA sequencing of first trimester plasma RNA, we tested whether the identification of pregnancies at risk of developing pre-eclampsia with or without preterm birth or growth restriction is possible
Externí odkaz:
https://doaj.org/article/3ef67a8e8858492f80308c0b8c2b1912
Autor:
Silvia D’Ambrosi, Allerdien Visser, Mafalda Antunes-Ferreira, Ankie Poutsma, Stavros Giannoukakos, Nik Sol, Siamack Sabrkhany, Idris Bahce, Marijke J. E. Kuijpers, Mirjam G. A. Oude Egbrink, Arjan W. Griffioen, Myron G. Best, Danijela Koppers-Lalic, Cees Oudejans, Thomas Würdinger
Publikováno v:
Cancers, Vol 13, Iss 18, p 4644 (2021)
Tumor-educated Platelets (TEPs) have emerged as rich biosources of cancer-related RNA profiles in liquid biopsies applicable for cancer detection. Although human blood platelets have been found to be enriched in circular RNA (circRNA), no studies hav
Externí odkaz:
https://doaj.org/article/4ab2559bf26d4f2aa61d22c9dcb495b1
Autor:
Cees Oudejans, Ankie Poutsma, Omar Michel, Joyce Mulders, Allerdien Visser, Marie van Dijk, Tessa Nauta, Anouk Bokslag, Walter Paulus, Andreas de Haas, Pieter Koolwijk, Christianne J M de Groot
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148313 (2016)
BACKGROUND:The physiological demands of pregnancy on the maternal cardiovascular system can catapult women into a metabolic syndrome that predisposes to atherosclerosis in later life. We sought to identify the nature of the epigenomic changes associa
Externí odkaz:
https://doaj.org/article/e63951386f74447693bb0649ce9bc1d0
Autor:
Remco Keijser, Erik A. Sistermans, Daoud Sie, Naomi Min, Eva Pajkrt, Joyce Mulders, Aldo Jongejan, Ankie Poutsma, Di-Jan Wigman, Tarah van den Berkmortel, Thomas Wurdinger, Allerdien Visser, Cees B.M. Oudejans, Vera Manders, Myron G. Best, Gijs B. Afink, Marjon A. de Boer, Britt Blanken
Publikováno v:
Oudejans, C, Manders, V, Visser, A, Keijser, R, Min, N, Poutsma, A, Mulders, J, van den Berkmortel, T, Wigman, D-J, Blanken, B, Jongejan, A, Pajkrt, E, de Boer, M, Sistermans, E A, Sie, D, Best, M G, Würdinger, T & Afink, G 2021, ' Circular RNA Sequencing of Maternal Platelets: A Novel Tool for the Identification of Pregnancy-Specific Biomarkers ', Clinical Chemistry, vol. 67, no. 3, pp. 508-517 . https://doi.org/10.1093/clinchem/hvaa249
Clinical chemistry, 67(3), 508-517. American Association for Clinical Chemistry Inc.
Clinical Chemistry, 67(3), 508-517
Clinical chemistry, 67(3), 508-517. American Association for Clinical Chemistry Inc.
Clinical Chemistry, 67(3), 508-517
Background In the first trimester of pregnancy, the maternal platelet is directly involved in a positive feedback mechanism that facilitates invasion of the extravillous trophoblast into the maternal spiral arteries. Dysfunctional trophoblast invasio
Autor:
Remco Keijser, Vera Manders, Gijs B. Afink, Allerdien Visser, Cees B.M. Oudejans, Thomas Wurdinger, Marjon A. de Boer, Daoud Sie, Marjolein Hortensius, Naomi Min, Eva Pajkrt, Tarah van den Berkmortel, Ankie Poutsma, Joyce Mulders, Myron G. Best, Aldo Jongejan, Erik A. Sistermans
Publikováno v:
Scientific reports, 10(1). Nature Publishing Group
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, 10(1):21857. Nature Publishing Group
Scientific Reports
Manders, V, Visser, A, Keijser, R, Min, N, Poutsma, A, Mulders, J, van den Berkmortel, T, Hortensius, M, Jongejan, A, Pajkrt, E, Sistermans, E A, Sie, D, Best, M G, Würdinger, T, de Boer, M, Afink, G & Oudejans, C 2020, ' The bivariate NRIP1/ZEB2 RNA marker permits non-invasive presymptomatic screening of pre-eclampsia ', Scientific Reports, vol. 10, no. 1, 21857 . https://doi.org/10.1038/s41598-020-79008-4
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, 10(1):21857. Nature Publishing Group
Scientific Reports
Manders, V, Visser, A, Keijser, R, Min, N, Poutsma, A, Mulders, J, van den Berkmortel, T, Hortensius, M, Jongejan, A, Pajkrt, E, Sistermans, E A, Sie, D, Best, M G, Würdinger, T, de Boer, M, Afink, G & Oudejans, C 2020, ' The bivariate NRIP1/ZEB2 RNA marker permits non-invasive presymptomatic screening of pre-eclampsia ', Scientific Reports, vol. 10, no. 1, 21857 . https://doi.org/10.1038/s41598-020-79008-4
Using genome-wide transcriptome analysis by RNA sequencing of first trimester plasma RNA, we tested whether the identification of pregnancies at risk of developing pre-eclampsia with or without preterm birth or growth restriction is possible between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07abb76af103f26a15b2f3b9af2f0e27
https://pure.amc.nl/en/publications/the-bivariate-nrip1zeb2-rna-marker-permits-noninvasive-presymptomatic-screening-of-preeclampsia(76c75a07-91ee-43ec-b08e-9af2d9856631).html
https://pure.amc.nl/en/publications/the-bivariate-nrip1zeb2-rna-marker-permits-noninvasive-presymptomatic-screening-of-preeclampsia(76c75a07-91ee-43ec-b08e-9af2d9856631).html
Autor:
Walter Paulus, Ankie Poutsma, Pieter Koolwijk, Marie van Dijk, Omar J. Michel, Cees B.M. Oudejans, Anouk Bokslag, Joyce Mulders, Tessa Nauta, Allerdien Visser, Andreas de Haas, Christianne J.M. de Groot
Publikováno v:
Oudejans, C, Poutsma, A, Michel, O, Mulders, J, Visser, A, van Dijk, M, Nauta, T, Bokslag, A, Paulus, W, de Haas, A, Koolwijk, P & de Groot, C J M 2016, ' Genome-Wide Identification of Epigenetic Hotspots Potentially Related to Cardiovascular Risk in Adult Women after a Complicated Pregnancy ', PLoS ONE, vol. 11, no. 2, e0148313 . https://doi.org/10.1371/journal.pone.0148313
PLoS ONE, Vol 11, Iss 2, p e0148313 (2016)
PLoS ONE
PLoS ONE, 11(2):e0148313. Public Library of Science
PLoS ONE, Vol 11, Iss 2, p e0148313 (2016)
PLoS ONE
PLoS ONE, 11(2):e0148313. Public Library of Science
Background The physiological demands of pregnancy on the maternal cardiovascular system can catapult women into a metabolic syndrome that predisposes to atherosclerosis in later life. We sought to identify the nature of the epigenomic changes associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18829e7886090caa02b99e3816625585
https://research.vumc.nl/en/publications/2a2953b6-04b9-446c-ac5f-cb94e335de77
https://research.vumc.nl/en/publications/2a2953b6-04b9-446c-ac5f-cb94e335de77
Autor:
Joyce Mulders, Marie van Dijk, Daoud Sie, Hari K. Thulluru, Ankie Poutsma, Gunilla Kleiverda, Omar J. Michel, Cees B.M. Oudejans, Augusta M. A. Lachmeijer, Sandra Windhorst
Publikováno v:
van Dijk, M, Thulluru, H K, Mulders, J, Michel, O J, Poutsma, A, Windhorst, S, Kleiverda, G, Sie, D L S, Lachmeijer, A M A & Oudejans, C B M 2012, ' HELLP babies link a novel lincRNA to the trophoblast cell cycle ', Journal of Clinical Investigation, vol. 122, no. 11, pp. 4003-4011 . https://doi.org/10.1172/JCI65171
Journal of Clinical Investigation, 122(11), 4003-4011. The American Society for Clinical Investigation
Journal of Clinical Investigation, 122(11), 4003-4011. The American Society for Clinical Investigation
The HELLP syndrome is a pregnancy-associated disease inducing hemolysis, elevated liver enzymes, and low platelets in the mother. Although the HELLP symptoms occur in the third trimester in the mother, the origin of the disease can be found in the fi
Autor:
Robert Veerhuis, Cees B.M. Oudejans, Wiep Scheper, Jan van Bezu, Annemieke J.M. Rozemuller, Marie van Dijk, Marinus A. Blankenstein, Ankie Poutsma
Publikováno v:
Journal of Alzheimer's Disease, 19(2), 673-679. IOS Press
Journal of Alzheimer s disease, 19(2), 673-679. IOS Press
van Dijk, M, van Bezu, J, Poutsma, A, Veerhuis, R, Rozemuller, A J, Scheper, W, Blankenstein, M A & Oudejans, C B M 2010, ' The Pre-Eclampsia Gene STOX1 Controls a Conserved Pathway in Placenta and Brain Upregulated in Late-Onset Alzheimer's Disease ', Journal of Alzheimer's Disease, vol. 19, no. 2, pp. 673-679 . https://doi.org/10.3233/JAD-2010-1265
Journal of Alzheimer s disease, 19(2), 673-679. IOS Press
van Dijk, M, van Bezu, J, Poutsma, A, Veerhuis, R, Rozemuller, A J, Scheper, W, Blankenstein, M A & Oudejans, C B M 2010, ' The Pre-Eclampsia Gene STOX1 Controls a Conserved Pathway in Placenta and Brain Upregulated in Late-Onset Alzheimer's Disease ', Journal of Alzheimer's Disease, vol. 19, no. 2, pp. 673-679 . https://doi.org/10.3233/JAD-2010-1265
Pre-eclampsia and late-onset Alzheimer's disease (LOAD) share no clinical features. In contrast to these clinical dissimilarities, striking parallels exist between the (epi)genetic features associated with pre-eclampsia and LOAD for the genes located
Autor:
Marie van Dijk, Allerdien Visser, Cees B.M. Oudejans, Ankie Poutsma, Kwadwo M.L. Buabeng, Roel C. van der Schors
Publikováno v:
van Dijk, M, Visser, A, Buabeng, K M L, Poutsma, A, van der Schors, R C & Oudejans, C B M 2015, ' Mutations within the LINC-HELLP non-coding RNA differentially bind ribosomal and RNA splicing complexes and negatively affect trophoblast differentiation ', Human Molecular Genetics, vol. 24, no. 19, pp. 5475-5485 . https://doi.org/10.1093/hmg/ddv274
Human Molecular Genetics, 24(19), 5475-5485. Oxford University Press
Human Molecular Genetics, 24(19), 5475-5485. Oxford University Press
LINC-HELLP, showing chromosomal linkage with the pregnancy-specific HELLP syndrome in Dutch families, reduces differentiation from a proliferative to an invasive phenotype of first-trimester extravillous trophoblasts. Here we show that mutations in L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f5562af5bebb5746e007c9c67e6bc3
https://research.vumc.nl/en/publications/8e20de10-7a6a-4111-9224-78f5a6916b2e
https://research.vumc.nl/en/publications/8e20de10-7a6a-4111-9224-78f5a6916b2e
Autor:
Ankie Poutsma, Marjan M. Weiss, Marie van Dijk, Rob Janssen, Erik A. Sistermans, Omar J. Michel, Danny Incarnato, Gunilla Kleiverda, Cees B.M. Oudejans, Rob Habets, Salvatore Oliviero, Reynir Arngrímsson
Publikováno v:
Oudejans, C B M, Michel, O J, Janssen, R, Habets, R, Poutsma, A, Sistermans, E A, Weiss, M M, Incarnato, D, Oliviero, S, Kleiverda, G, van Dijk, M & Arngrimsson, R 2015, ' Susceptibility allele-specific loss of miR-1324-mediated silencing of the INO80B chromatin-assembly complex gene in pre-eclampsia ', Human Molecular Genetics, vol. 24, no. 1, pp. 118-127 . https://doi.org/10.1093/hmg/ddu423
Human Molecular Genetics, 24(1), 118-127. Oxford University Press
Human Molecular Genetics, 24(1), 118-127. Oxford University Press
In humans, the elucidation of the genetics underlying multifactorial diseases such as pre-eclampsia remains complex. Given the current day availability of genome-wide linkage- and expression data pools, we applied pathway-guided genome-wide meta-anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3525953b19ca67512f46c684413685e
https://research.vumc.nl/en/publications/44f793d4-cc9d-4491-a8ed-3809ff40a527
https://research.vumc.nl/en/publications/44f793d4-cc9d-4491-a8ed-3809ff40a527