Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Anke Wahler"'
Autor:
Kerstin Ott, Taneli Heikkinen, Kimmo K. Lehtimäki, Kaisa Paldanius, Jukka Puoliväli, Raimo Pussinen, Emile Andriambeloson, Bertrand Huyard, Stéphanie Wagner, Cathrin Schnack, Anke Wahler, Bjoern von Einem, Christine A. F. von Arnim, Yvonne Burmeister, Kathrin Weyer, Bernd Seilheimer
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionCognitive impairment associated with old age or various brain disorders may be very disabling for affected individuals, placing their carers and public health services under considerable stress. The standard-of-care drugs produce only tra
Externí odkaz:
https://doaj.org/article/f12ba6f9b38b48368ec02d6e6c2f5b15
Autor:
Bjoern von Einem, Anke Wahler, Tobias Schips, Alberto Serrano-Pozo, Christian Proepper, Tobias M Boeckers, Angelika Rueck, Thomas Wirth, Bradley T Hyman, Karin M Danzer, Dietmar R Thal, Christine A F von Arnim
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129047 (2015)
Proteolytic processing of amyloid-β precursor protein (APP) by beta-site APP cleaving enzyme 1 (BACE1) is the initial step in the production of amyloid beta (Aβ), which accumulates in senile plaques in Alzheimer's disease (AD). Essential for this c
Externí odkaz:
https://doaj.org/article/22b8744c88d84df4afb3d006d8a82a9f
Autor:
Dudley K. Strickland, Ithan D. Peltan, Christine A. F. von Arnim, Cathrin Schnack, Bradley T. Hyman, Christian Pröpper, Tobias M. Boeckers, Ilona E. Keller, Björn von Einem, Anja Silke Beyer, Anke Wahler
Publikováno v:
Biochemical Journal. 450:333-343
APP (amyloid precursor protein) and LRP1 (low-density lipoprotein receptor-related protein 1) have been implicated in the pathogenesis of AD (Alzheimer's disease). They are functionally linked by Fe65, a PTB (phosphotyrosine-binding)-domain-containin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a295775a527846a33941c5d16c681e26
https://doi.org/10.1042/bj20121100
https://doi.org/10.1042/bj20121100
Autor:
Tobias M. Boeckers, Tobias G. Schips, Christine A. F. von Arnim, Karin M Danzer, Anke Wahler, Thomas Wirth, Bradley T. Hyman, Christian Proepper, Alberto Serrano-Pozo, Dietmar Rudolf Thal, Bjoern von Einem, Angelika Rueck
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 6, p e0129047 (2015)
PLoS ONE, Vol 10, Iss 6, p e0129047 (2015)
Proteolytic processing of amyloid-β precursor protein (APP) by beta-site APP cleaving enzyme 1 (BACE1) is the initial step in the production of amyloid beta (Aβ), which accumulates in senile plaques in Alzheimer's disease (AD). Essential for this c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f5f5b95aadd9fbc1759f63868afc19e
http://europepmc.org/articles/PMC4460050
http://europepmc.org/articles/PMC4460050
Reduced cGMP levels in CSF of AD patients correlate with severity of dementia and current depression
Autor:
Anke Wahler, Pauline Gummert, Christine A. F. von Arnim, Florian Schmid, Raphael Hesse, Hayrettin Tumani, Katja S. Kroker, Markus Otto, Holger Rosenbrock, Ludwig Lausser, Hans A. Kestler, Cathrin Schnack
Publikováno v:
Alzheimer's Research & Therapy
Background Alzheimer’s disease (AD) is a neurodegenerative disorder, primarily affecting memory. That disorder is thought to be a consequence of neuronal network disturbances and synapse loss. Decline in cognitive function is associated with a high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cde1cac793e6d60df17a4d6f291927d