Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Anke Reining"'
Publikováno v:
Nature. 499:355-359
In the human pathogen Vibrio vulnificus, the riboswitch regulating gene expression of the adenosine deaminase is shown to exist in three distinct stable conformational states; this three-state mechanism allows control of gene expression over a broad
Publikováno v:
Current opinion in structural biology. 30
Riboswitches are structured regions of mRNAs that modulate gene expression in response to specific binding of low molecular-weight ligands. They function by induced transitions between different functional conformations. The standard model assumed th
Autor:
Harald Schwalbe, Kai Schlepckow, Yong-Boum Kim, Senada Nozinovic, Jens Wöhnert, Anke Reining, Jonas Noeske
Publikováno v:
RNA Biology
We report here an in-depth characterization of the aptamer domain of the transcriptional adenine-sensing riboswitch (pbuE) by NMR and fluorescence spectroscopy. By NMR studies, the structure of two aptamer sequences with different lengths of the heli
Autor:
Boris Fürtig, Alexander Heckel, Anke Reining, Harald Schwalbe, Florian Sochor, Eva Marie Oberhauser
Publikováno v:
Current Protocols in Nucleic Acid Chemistry
Unlike proteins, a given RNA sequence can adopt more than a single conformation. The two (or more) conformations are long-lived and have similar stabilities, but interconvert only slowly. Such bi- or multistability is often linked to the biological f